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Items: 1 to 20 of 139

1.

Synthesis and cellular characterization of novel isoxazolo- and thiazolohydrazinylidene-chroman-2,4-diones on cancer and non-cancer cell growth and death.

Jashari A, Imeri F, Ballazhi L, Shabani A, Mikhova B, Dräger G, Popovski E, Huwiler A.

Bioorg Med Chem. 2014 May 1;22(9):2655-61. doi: 10.1016/j.bmc.2014.03.026. Epub 2014 Mar 24.

PMID:
24721833
2.

Potential antiproliferative effect of isoxazolo- and thiazolo coumarin derivatives on breast cancer mediated bone and lung metastases.

Ballazhi L, Popovski E, Jashari A, Imeri F, Ibrahimi I, Mikhova B, Mladenovska K.

Acta Pharm. 2015 Mar;65(1):53-63. doi: 10.1515/acph-2015-0002.

PMID:
25781704
3.

Synthesis and biological evaluation of novel isoxazoles and triazoles linked 6-hydroxycoumarin as potent cytotoxic agents.

Shakeel-u-Rehman, Masood-ur-Rahman, Tripathi VK, Singh J, Ara T, Koul S, Farooq S, Kaul A.

Bioorg Med Chem Lett. 2014 Sep 1;24(17):4243-6. doi: 10.1016/j.bmcl.2014.07.031. Epub 2014 Jul 17.

PMID:
25088398
4.

Coumarin polysulfides inhibit cell growth and induce apoptosis in HCT116 colon cancer cells.

Saidu NE, Valente S, Bana E, Kirsch G, Bagrel D, Montenarh M.

Bioorg Med Chem. 2012 Feb 15;20(4):1584-93. doi: 10.1016/j.bmc.2011.12.032. Epub 2011 Dec 30.

PMID:
22264758
5.

Novel acylated steroidal glycosides from Caralluma tuberculata induce caspase-dependent apoptosis in cancer cells.

Waheed A, Barker J, Barton SJ, Khan GM, Najm-Us-Saqib Q, Hussain M, Ahmed S, Owen C, Carew MA.

J Ethnopharmacol. 2011 Oct 11;137(3):1189-96. doi: 10.1016/j.jep.2011.07.049. Epub 2011 Jul 26.

PMID:
21820042
6.

Synthesis and biological evaluation of 4-(1,2,3-triazol-1-yl)coumarin derivatives as potential antitumor agents.

Zhang W, Li Z, Zhou M, Wu F, Hou X, Luo H, Liu H, Han X, Yan G, Ding Z, Li R.

Bioorg Med Chem Lett. 2014 Feb 1;24(3):799-807. doi: 10.1016/j.bmcl.2013.12.095. Epub 2013 Dec 29.

PMID:
24418772
7.

Antiproliferative and apoptotic effects of compounds from the flower of Mammea siamensis (Miq.) T. Anders. on human cancer cell lines.

Tung NH, Uto T, Sakamoto A, Hayashida Y, Hidaka Y, Morinaga O, Lhieochaiphant S, Shoyama Y.

Bioorg Med Chem Lett. 2013 Jan 1;23(1):158-62. doi: 10.1016/j.bmcl.2012.10.127. Epub 2012 Nov 7.

PMID:
23206866
8.

Synthesis of novel building blocks of benzosuberone bearing coumarin moieties and their evaluation as potential anticancer agents.

Yadagiri B, Holagunda UD, Bantu R, Nagarapu L, Kumar CG, Pombala S, Sridhar B.

Eur J Med Chem. 2014 May 22;79:260-5. doi: 10.1016/j.ejmech.2014.04.015. Epub 2014 Apr 5.

PMID:
24742385
9.

Synthesis and cytotoxic activity of non-naturally substituted 4-oxycoumarin derivatives.

Serra S, Chicca A, Delogu G, Vázquez-Rodríguez S, Santana L, Uriarte E, Casu L, Gertsch J.

Bioorg Med Chem Lett. 2012 Sep 15;22(18):5791-4. doi: 10.1016/j.bmcl.2012.07.099. Epub 2012 Aug 5. Erratum in: Bioorg Med Chem Lett. 2012 Nov 1;22(21):6775.

PMID:
22901895
10.

Some new indole-coumarin hybrids; Synthesis, anticancer and Bcl-2 docking studies.

Kamath PR, Sunil D, Ajees AA, Pai KS, Das S.

Bioorg Chem. 2015 Dec;63:101-9. doi: 10.1016/j.bioorg.2015.10.001. Epub 2015 Oct 9.

PMID:
26469742
11.

Synthesis of novel diazaphosphinanes coumarin derivatives with promoted cytotoxic and anti-tyrosinase activities.

Gardelly M, Trimech B, Belkacem MA, Harbach M, Abdelwahed S, Mosbah A, Bouajila J, Ben Jannet H.

Bioorg Med Chem Lett. 2016 May 15;26(10):2450-2454. doi: 10.1016/j.bmcl.2016.03.108. Epub 2016 Mar 31.

PMID:
27080182
12.

Palladium(II) saccharinate complexes with bis(2-pyridylmethyl)amine induce cell death by apoptosis in human breast cancer cells in vitro.

Ari F, Ulukaya E, Sarimahmut M, Yilmaz VT.

Bioorg Med Chem. 2013 Jun 1;21(11):3016-21. doi: 10.1016/j.bmc.2013.03.073. Epub 2013 Apr 6.

PMID:
23601820
13.

Design and Synthesis of Coumarin Derivatives as Novel PI3K Inhibitors.

Ma CC, Liu ZP.

Anticancer Agents Med Chem. 2017;17(3):395-403. doi: 10.2174/1871520616666160223120207.

PMID:
26902599
14.
15.

Discovery of novel osthole derivatives as potential anti-breast cancer treatment.

You L, An R, Wang X, Li Y.

Bioorg Med Chem Lett. 2010 Dec 15;20(24):7426-8. doi: 10.1016/j.bmcl.2010.10.027. Epub 2010 Nov 2.

PMID:
21051232
16.

Neo-tanshinlactone inspired synthesis, in vitro evaluation of novel substituted benzocoumarin derivatives as potent anti-breast cancer agents.

Sashidhara KV, Rosaiah JN, Kumar M, Gara RK, Nayak LV, Srivastava K, Bid HK, Konwar R.

Bioorg Med Chem Lett. 2010 Dec 1;20(23):7127-31. doi: 10.1016/j.bmcl.2010.09.040. Epub 2010 Sep 21.

PMID:
20951035
17.

A novel hydroxamic acid compound, BMD188, demonstrates anti-prostate cancer effects by inducing apoptosis. I: In vitro studies.

Li L, Zhu Z, Joshi B, Porter AT, Tang DG.

Anticancer Res. 1999 Jan-Feb;19(1A):51-60.

PMID:
10226524
18.

Synthesis and in vitro evaluation of 3-(4-nitrophenyl)coumarin derivatives in tumor cell lines.

Musa MA, Latinwo LM, Virgile C, Badisa VL, Gbadebo AJ.

Bioorg Chem. 2015 Feb;58:96-103. doi: 10.1016/j.bioorg.2014.11.009. Epub 2014 Nov 29.

PMID:
25553414
19.

A concentrated aglycone isoflavone preparation (GCP) that demonstrates potent anti-prostate cancer activity in vitro and in vivo.

Bemis DL, Capodice JL, Desai M, Buttyan R, Katz AE.

Clin Cancer Res. 2004 Aug 1;10(15):5282-92.

20.

Taxol-induced growth arrest and apoptosis is associated with the upregulation of the Cdk inhibitor, p21WAF1/CIP1, in human breast cancer cells.

Choi YH, Yoo YH.

Oncol Rep. 2012 Dec;28(6):2163-9. doi: 10.3892/or.2012.2060. Epub 2012 Sep 26.

PMID:
23023313

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