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Items: 1 to 20 of 160

1.

A complex signaling network involving protein kinase CK2 is required for hepatitis C virus core protein-mediated modulation of the iron-regulatory hepcidin gene expression.

Foka P, Dimitriadis A, Kyratzopoulou E, Giannimaras DA, Sarno S, Simos G, Georgopoulou U, Mamalaki A.

Cell Mol Life Sci. 2014 Nov;71(21):4243-58. doi: 10.1007/s00018-014-1621-4. Epub 2014 Apr 10.

PMID:
24718935
2.

Ceramide Induces Human Hepcidin Gene Transcription through JAK/STAT3 Pathway.

Lu S, Natarajan SK, Mott JL, Kharbanda KK, Harrison-Findik DD.

PLoS One. 2016 Jan 25;11(1):e0147474. doi: 10.1371/journal.pone.0147474. eCollection 2016.

3.

Saturated fatty acids induce post-transcriptional regulation of HAMP mRNA via AU-rich element-binding protein, human antigen R (HuR).

Lu S, Mott JL, Harrison-Findik DD.

J Biol Chem. 2015 Oct 2;290(40):24178-89. doi: 10.1074/jbc.M115.648212. Epub 2015 Aug 24.

4.

Alterations in the iron homeostasis network: A driving force for macrophage-mediated hepatitis C virus persistency.

Foka P, Dimitriadis A, Karamichali E, Kyratzopoulou E, Giannimaras D, Koskinas J, Varaklioti A, Mamalaki A, Georgopoulou U.

Virulence. 2016 Aug 17;7(6):679-90. doi: 10.1080/21505594.2016.1175700. Epub 2016 Apr 8.

5.

Gluconeogenic signals regulate iron homeostasis via hepcidin in mice.

Vecchi C, Montosi G, Garuti C, Corradini E, Sabelli M, Canali S, Pietrangelo A.

Gastroenterology. 2014 Apr;146(4):1060-9. doi: 10.1053/j.gastro.2013.12.016. Epub 2013 Dec 17.

6.

Activated macrophages induce hepcidin expression in HuH7 hepatoma cells.

Matak P, Chaston TB, Chung B, Srai SK, McKie AT, Sharp PA.

Haematologica. 2009 Jun;94(6):773-80. doi: 10.3324/haematol.2008.003400. Epub 2009 May 19.

7.

Hypoxia inhibits hepcidin expression in HuH7 hepatoma cells via decreased SMAD4 signaling.

Chaston TB, Matak P, Pourvali K, Srai SK, McKie AT, Sharp PA.

Am J Physiol Cell Physiol. 2011 Apr;300(4):C888-95. doi: 10.1152/ajpcell.00121.2010. Epub 2011 Feb 2.

8.

The small molecule, genistein, increases hepcidin expression in human hepatocytes.

Zhen AW, Nguyen NH, Gibert Y, Motola S, Buckett P, Wessling-Resnick M, Fraenkel E, Fraenkel PG.

Hepatology. 2013 Oct;58(4):1315-25. doi: 10.1002/hep.26490. Epub 2013 Aug 19.

9.

Friend of GATA and GATA-6 modulate the transcriptional up-regulation of hepcidin in hepatocytes during inflammation.

Bagu ET, Layoun A, Calvé A, Santos MM.

Biometals. 2013 Dec;26(6):1051-65. doi: 10.1007/s10534-013-9683-6. Epub 2013 Nov 1.

PMID:
24179092
10.

Hepatitis C virus core protein differently regulates the JAK-STAT signaling pathway under interleukin-6 and interferon-gamma stimuli.

Hosui A, Ohkawa K, Ishida H, Sato A, Nakanishi F, Ueda K, Takehara T, Kasahara A, Sasaki Y, Hori M, Hayashi N.

J Biol Chem. 2003 Aug 1;278(31):28562-71. Epub 2003 May 22.

11.

Peroxiredoxin-2: A Novel Regulator of Iron Homeostasis in Ineffective Erythropoiesis.

Matte A, De Falco L, Federti E, Cozzi A, Iolascon A, Levi S, Mohandas N, Zamo A, Bruno M, Lebouef C, Janin A, Siciliano A, Ganz T, Federico G, Carlomagno F, Mueller S, Silva I, Carbone C, Melisi D, Kim DW, Choi SY, De Franceschi L.

Antioxid Redox Signal. 2018 Jan 1;28(1):1-14. doi: 10.1089/ars.2017.7051. Epub 2017 Sep 6.

PMID:
28793778
12.

PGC-1α regulates hepatic hepcidin expression and iron homeostasis in response to inflammation.

Qian J, Chen S, Huang Y, Shi X, Liu C.

Mol Endocrinol. 2013 Apr;27(4):683-92. doi: 10.1210/me.2012-1345. Epub 2013 Feb 25.

13.

A low-molecular-weight compound K7174 represses hepcidin: possible therapeutic strategy against anemia of chronic disease.

Fujiwara T, Ikeda T, Nagasaka Y, Okitsu Y, Katsuoka Y, Fukuhara N, Onishi Y, Ishizawa K, Ichinohasama R, Tomosugi N, Harigae H.

PLoS One. 2013 Sep 27;8(9):e75568. doi: 10.1371/journal.pone.0075568. eCollection 2013.

14.

Quercetin prevents ethanol-induced iron overload by regulating hepcidin through the BMP6/SMAD4 signaling pathway.

Tang Y, Li Y, Yu H, Gao C, Liu L, Chen S, Xing M, Liu L, Yao P.

J Nutr Biochem. 2014 Jun;25(6):675-82. doi: 10.1016/j.jnutbio.2014.02.009. Epub 2014 Mar 19.

PMID:
24746831
15.

Icariin regulates systemic iron metabolism by increasing hepatic hepcidin expression through Stat3 and Smad1/5/8 signaling.

Zhang M, Liu J, Guo W, Liu X, Liu S, Yin H.

Int J Mol Med. 2016 May;37(5):1379-88. doi: 10.3892/ijmm.2016.2545. Epub 2016 Apr 1.

PMID:
27035325
16.

Friend of GATA suppresses the GATA-induced transcription of hepcidin in hepatocytes through a GATA-regulatory element in the HAMP promoter.

Bagu ET, Santos MM.

J Mol Endocrinol. 2011 Nov 21;47(3):299-313. doi: 10.1530/JME-11-0060. Print 2011 Dec.

17.

Allogeneic transplantation, Fas signaling, and dysregulation of hepcidin.

Li X, Xu F, Karoopongse E, Marcondes AM, Lee K, Kowdley KV, Miao CH, Trobridge GD, Campbell JS, Deeg HJ.

Biol Blood Marrow Transplant. 2013 Aug;19(8):1210-9. doi: 10.1016/j.bbmt.2013.05.012. Epub 2013 May 22.

18.

Iron regulator hepcidin exhibits antiviral activity against hepatitis C virus.

Liu H, Trinh TL, Dong H, Keith R, Nelson D, Liu C.

PLoS One. 2012;7(10):e46631. doi: 10.1371/journal.pone.0046631. Epub 2012 Oct 22.

19.

Hepatitis C virus core protein regulates NANOG expression via the stat3 pathway.

Zhou JJ, Chen RF, Deng XG, Zhou Y, Ye X, Yu M, Tang J, He XY, Cheng D, Zeng B, Zhou QB, Li ZH.

FEBS Lett. 2014 Feb 14;588(4):566-73. doi: 10.1016/j.febslet.2013.11.041. Epub 2014 Jan 21.

20.

Genetic study of the hepcidin gene (HAMP) promoter and functional analysis of the c.-582A > G variant.

Parajes S, González-Quintela A, Campos J, Quinteiro C, Domínguez F, Loidi L.

BMC Genet. 2010 Dec 10;11:110. doi: 10.1186/1471-2156-11-110.

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