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Items: 1 to 20 of 68

1.

The H1-receptor antagonist cetirizine protects partially against cytokine- and hydrogen peroxide-induced β-TC6 cell death in vitro.

Anvari E, Fred RG, Welsh N.

Pancreas. 2014 May;43(4):624-9. doi: 10.1097/MPA.0000000000000076.

PMID:
24717804
2.

The H1-receptor antagonist cetirizine ameliorates high-fat diet-induced glucose intolerance in male C57BL/6 mice, but not diabetes outcome in female non-obese diabetic (NOD) mice.

Anvari E, Wang X, Sandler S, Welsh N.

Ups J Med Sci. 2015 Mar;120(1):40-6. doi: 10.3109/03009734.2014.967422. Epub 2014 Oct 7.

3.

Co-culture of neural crest stem cells (NCSC) and insulin producing beta-TC6 cells results in cadherin junctions and protection against cytokine-induced beta-cell death.

Ngamjariyawat A, Turpaev K, Vasylovska S, Kozlova EN, Welsh N.

PLoS One. 2013 Apr 17;8(4):e61828. doi: 10.1371/journal.pone.0061828. Print 2013.

5.

Tissue factor/factor VIIa signalling promotes cytokine-induced beta cell death and impairs glucose-stimulated insulin secretion from human pancreatic islets.

Edén D, Siegbahn A, Mokhtari D.

Diabetologia. 2015 Nov;58(11):2563-72. doi: 10.1007/s00125-015-3729-y. Epub 2015 Aug 14.

6.

Role of MKK3 and p38 MAPK in cytokine-induced death of insulin-producing cells.

Makeeva N, Myers JW, Welsh N.

Biochem J. 2006 Jan 1;393(Pt 1):129-39.

7.

Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action.

Shimizu T, Nishihira J, Watanabe H, Abe R, Ishibashi T, Shimizu H.

Clin Exp Allergy. 2004 Jan;34(1):103-9.

PMID:
14720269
8.

PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis.

Moore F, Colli ML, Cnop M, Esteve MI, Cardozo AK, Cunha DA, Bugliani M, Marchetti P, Eizirik DL.

Diabetes. 2009 Jun;58(6):1283-91. doi: 10.2337/db08-1510. Epub 2009 Mar 31.

9.

Perturbations in nuclear factor-kappaB or c-Jun N-terminal kinase pathways in pancreatic beta cells confer susceptibility to cytokine-induced cell death.

Thomas HE, Angstetra E, Fernandes RV, Mariana L, Irawaty W, Jamieson EL, Dudek NL, Kay TW.

Immunol Cell Biol. 2006 Feb;84(1):20-7. Epub 2005 Nov 7.

PMID:
16277639
10.

Fructus Xanthii extract protects against cytokine-induced damage in pancreatic beta-cells through suppression of NF-kappaB activation.

Song MY, Kim EK, Lee HJ, Park JW, Ryu DG, Kwon KB, Park BH.

Int J Mol Med. 2009 Apr;23(4):547-53.

PMID:
19288032
11.

Genistein protects pancreatic beta cells against cytokine-mediated toxicity.

Kim EK, Kwon KB, Song MY, Seo SW, Park SJ, Ka SO, Na L, Kim KA, Ryu DG, So HS, Park R, Park JW, Park BH.

Mol Cell Endocrinol. 2007 Nov 15;278(1-2):18-28. Epub 2007 Aug 15.

PMID:
17881116
12.

Radix asari extract protects pancreatic beta cells against cytokine-induced toxicity: implication of the NF-kappaB-iNOS signaling cascade.

Song MY, Kim KA, Lee SY, Kim EK, Lv N, Lee JH, Park JW, Ryu DG, Kwon KB, Park BH.

Int J Mol Med. 2007 Nov;20(5):769-75.

PMID:
17912472
13.

Exendin-4 protects beta-cells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway.

Ferdaoussi M, Abdelli S, Yang JY, Cornu M, Niederhauser G, Favre D, Widmann C, Regazzi R, Thorens B, Waeber G, Abderrahmani A.

Diabetes. 2008 May;57(5):1205-15. doi: 10.2337/db07-1214. Epub 2008 Feb 5.

14.
15.

Novel inhibitors of macrophage migration inhibitory factor prevent cytokine-induced beta cell death.

Vujicic M, Nikolic I, Krajnovic T, Cheng KF, VanPatten S, He M, Stosic-Grujicic S, Stojanovic I, Al-Abed Y, Saksida T.

Eur J Pharmacol. 2014 Oct 5;740:683-9. doi: 10.1016/j.ejphar.2014.06.009. Epub 2014 Jun 23.

PMID:
24967533
16.

Epigallocatechin-3-gallate protects pro-inflammatory cytokine induced injuries in insulin-producing cells through the mitochondrial pathway.

Zhang Z, Ding Y, Dai X, Wang J, Li Y.

Eur J Pharmacol. 2011 Nov 16;670(1):311-6. doi: 10.1016/j.ejphar.2011.08.033. Epub 2011 Sep 8.

PMID:
21925162
17.

Imatinib mesylate stimulates low-density lipoprotein receptor-related protein 1-mediated ERK phosphorylation in insulin-producing cells.

Fred RG, Boddeti SK, Lundberg M, Welsh N.

Clin Sci (Lond). 2015 Jan;128(1):17-28. doi: 10.1042/CS20130560.

PMID:
24865476
18.

Overexpression of SIRT1 protects pancreatic beta-cells against cytokine toxicity by suppressing the nuclear factor-kappaB signaling pathway.

Lee JH, Song MY, Song EK, Kim EK, Moon WS, Han MK, Park JW, Kwon KB, Park BH.

Diabetes. 2009 Feb;58(2):344-51. doi: 10.2337/db07-1795. Epub 2008 Nov 13.

19.

Involvement of P2X receptors in the regulation of insulin secretion, proliferation and survival in mouse pancreatic β-cells.

Ohtani M, Ohura K, Oka T.

Cell Physiol Biochem. 2011;28(2):355-66. doi: 10.1159/000331752. Epub 2011 Aug 16.

20.

A combined "omics" approach identifies N-Myc interactor as a novel cytokine-induced regulator of IRE1 protein and c-Jun N-terminal kinase in pancreatic beta cells.

Brozzi F, Gerlo S, Grieco FA, Nardelli TR, Lievens S, Gysemans C, Marselli L, Marchetti P, Mathieu C, Tavernier J, Eizirik DL.

J Biol Chem. 2014 Jul 25;289(30):20677-93.

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