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Items: 1 to 20 of 185

1.

The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease.

Varelas X.

Development. 2014 Apr;141(8):1614-26. doi: 10.1242/dev.102376. Review.

2.

The biology of YAP/TAZ: hippo signaling and beyond.

Piccolo S, Dupont S, Cordenonsi M.

Physiol Rev. 2014 Oct;94(4):1287-312. doi: 10.1152/physrev.00005.2014. Review.

PMID:
25287865
3.

The Hippo pathway effectors TAZ/YAP regulate dicer expression and microRNA biogenesis through Let-7.

Chaulk SG, Lattanzi VJ, Hiemer SE, Fahlman RP, Varelas X.

J Biol Chem. 2014 Jan 24;289(4):1886-91. doi: 10.1074/jbc.C113.529362. Epub 2013 Dec 9.

4.

Targeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer Therapy.

Juan WC, Hong W.

Genes (Basel). 2016 Aug 30;7(9). pii: E55. doi: 10.3390/genes7090055. Review.

5.

A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling.

Imajo M, Miyatake K, Iimura A, Miyamoto A, Nishida E.

EMBO J. 2012 Mar 7;31(5):1109-22. doi: 10.1038/emboj.2011.487. Epub 2012 Jan 10.

6.

Stem cell regulation by the Hippo pathway.

Hiemer SE, Varelas X.

Biochim Biophys Acta. 2013 Feb;1830(2):2323-34. doi: 10.1016/j.bbagen.2012.07.005. Epub 2012 Jul 20. Review.

PMID:
22824335
7.

The Hippo Pathway and YAP/TAZ-TEAD Protein-Protein Interaction as Targets for Regenerative Medicine and Cancer Treatment.

Santucci M, Vignudelli T, Ferrari S, Mor M, Scalvini L, Bolognesi ML, Uliassi E, Costi MP.

J Med Chem. 2015 Jun 25;58(12):4857-73. doi: 10.1021/jm501615v. Epub 2015 Mar 11. Review.

PMID:
25719868
8.

The Hippo-YAP pathway: new connections between regulation of organ size and cancer.

Zhao B, Lei QY, Guan KL.

Curr Opin Cell Biol. 2008 Dec;20(6):638-46. doi: 10.1016/j.ceb.2008.10.001. Epub 2008 Nov 18. Review.

9.

The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.

Varelas X, Samavarchi-Tehrani P, Narimatsu M, Weiss A, Cockburn K, Larsen BG, Rossant J, Wrana JL.

Dev Cell. 2010 Dec 14;19(6):831-44. doi: 10.1016/j.devcel.2010.11.012.

10.

The transcriptional regulators TAZ and YAP direct transforming growth factor β-induced tumorigenic phenotypes in breast cancer cells.

Hiemer SE, Szymaniak AD, Varelas X.

J Biol Chem. 2014 May 9;289(19):13461-74. doi: 10.1074/jbc.M113.529115. Epub 2014 Mar 19.

11.

Molecular pathways: YAP and TAZ take center stage in organ growth and tumorigenesis.

Piccolo S, Cordenonsi M, Dupont S.

Clin Cancer Res. 2013 Sep 15;19(18):4925-30. doi: 10.1158/1078-0432.CCR-12-3172. Epub 2013 Jun 24.

12.

Hippo Pathway: An Emerging Regulator of Craniofacial and Dental Development.

Wang J, Martin JF.

J Dent Res. 2017 Oct;96(11):1229-1237. doi: 10.1177/0022034517719886. Epub 2017 Jul 12. Review.

PMID:
28700256
13.

[Regulation of differentiation of mesenchymal stem cells by the Hippo pathway effectors TAZ/YAP].

Men T, Piao SH, Teng CB.

Yi Chuan. 2013 Nov;35(11):1283-90. Review. Chinese.

PMID:
24579311
14.

Distinct polarity cues direct Taz/Yap and TGFβ receptor localization to differentially control TGFβ-induced Smad signaling.

Narimatsu M, Samavarchi-Tehrani P, Varelas X, Wrana JL.

Dev Cell. 2015 Mar 9;32(5):652-6. doi: 10.1016/j.devcel.2015.02.019.

15.

A Computational Model of YAP/TAZ Mechanosensing.

Sun M, Spill F, Zaman MH.

Biophys J. 2016 Jun 7;110(11):2540-2550. doi: 10.1016/j.bpj.2016.04.040.

16.

NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway.

Habbig S, Bartram MP, Müller RU, Schwarz R, Andriopoulos N, Chen S, Sägmüller JG, Hoehne M, Burst V, Liebau MC, Reinhardt HC, Benzing T, Schermer B.

J Cell Biol. 2011 May 16;193(4):633-42. doi: 10.1083/jcb.201009069. Epub 2011 May 9.

17.

The Hippo pathway in normal development and cancer.

Maugeri-Saccà M, De Maria R.

Pharmacol Ther. 2018 Jan 2. pii: S0163-7258(17)30309-1. doi: 10.1016/j.pharmthera.2017.12.011. [Epub ahead of print] Review.

PMID:
29305295
18.

[Role of Hippo-YAP/TAZ signaling pathway in mechanotransduction.]

Ishihara E, Nishina H.

Clin Calcium. 2016;26(12):1751-1756. Japanese.

PMID:
27885187
19.

Insights into the regulation of Yap/Taz from cellular systems and mouse models.

Du W, Du W, Wan M, Zhou X, Xu X, Zheng L.

Curr Stem Cell Res Ther. 2017 Jan 2. [Epub ahead of print]

PMID:
28042766
20.

Transcriptional regulators in the Hippo signaling pathway control organ growth in Xenopus tadpole tail regeneration.

Hayashi S, Ochi H, Ogino H, Kawasumi A, Kamei Y, Tamura K, Yokoyama H.

Dev Biol. 2014 Dec 1;396(1):31-41. doi: 10.1016/j.ydbio.2014.09.018. Epub 2014 Oct 2.

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