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Items: 1 to 20 of 88

1.

Pancreatic cancer induced by in vivo electroporation-enhanced sleeping beauty transposon gene delivery system in mouse.

Park JS, Lim KM, Park SG, Jung SY, Choi HJ, Lee DH, Kim WJ, Hong SM, Yu ES, Son WC.

Pancreas. 2014 May;43(4):614-8. doi: 10.1097/MPA.0000000000000102.

PMID:
24713671
2.

Induction of rat liver tumor using the Sleeping Beauty transposon and electroporation.

Park JS, Kim BH, Park SG, Jung SY, Lee DH, Son WC.

Biochem Biophys Res Commun. 2013 May 10;434(3):589-93. doi: 10.1016/j.bbrc.2013.03.119. Epub 2013 Apr 10.

PMID:
23583385
3.

Sleeping Beauty transposon system harboring HRAS, c-Myc and shp53 induces sarcomatoid carcinomas in mouse skin.

Jung S, Ro SW, Jung G, Ju HL, Yu ES, Son WC.

Oncol Rep. 2013 Apr;29(4):1293-8. doi: 10.3892/or.2013.2264. Epub 2013 Jan 31.

4.

Electroporation markedly improves Sleeping Beauty transposon-induced tumorigenesis in mice.

Jung S, Choi HJ, Park HK, Jo W, Jang S, Ryu JE, Kim WJ, Yu ES, Son WC.

Cancer Gene Ther. 2014 Aug;21(8):333-9. doi: 10.1038/cgt.2014.33. Epub 2014 Jul 4.

PMID:
24992966
5.

Identification of Sleeping Beauty transposon insertions in solid tumors using linker-mediated PCR.

Janik CL, Starr TK.

J Vis Exp. 2013 Feb 1;(72):e50156. doi: 10.3791/50156.

6.

A human cancer xenograft model utilizing normal pancreatic duct epithelial cells conditionally transformed with defined oncogenes.

Inagawa Y, Yamada K, Yugawa T, Ohno S, Hiraoka N, Esaki M, Shibata T, Aoki K, Saya H, Kiyono T.

Carcinogenesis. 2014 Aug;35(8):1840-6. doi: 10.1093/carcin/bgu112. Epub 2014 May 24.

PMID:
24858378
7.

Targeted delivery of in situ PCR-amplified Sleeping Beauty transposon genes to cancer cells with lipid-based nanoparticle-like protocells.

Ma K, Fu D, Yu D, Cui C, Wang L, Guo Z, Mao C.

Biomaterials. 2017 Mar;121:55-63. doi: 10.1016/j.biomaterials.2016.12.033. Epub 2017 Jan 2.

PMID:
28081459
8.

Somatic integration of an oncogene-harboring Sleeping Beauty transposon models liver tumor development in the mouse.

Carlson CM, Frandsen JL, Kirchhof N, McIvor RS, Largaespada DA.

Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17059-64. Epub 2005 Nov 14.

9.

Transposon-mediated mutagenesis in somatic cells: identification of transposon-genomic DNA junctions.

Largaespada DA, Collier LS.

Methods Mol Biol. 2008;435:95-108. doi: 10.1007/978-1-59745-232-8_7.

10.

Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.

Hermann PC, Sancho P, Cañamero M, Martinelli P, Madriles F, Michl P, Gress T, de Pascual R, Gandia L, Guerra C, Barbacid M, Wagner M, Vieira CR, Aicher A, Real FX, Sainz B Jr, Heeschen C.

Gastroenterology. 2014 Nov;147(5):1119-33.e4. doi: 10.1053/j.gastro.2014.08.002. Epub 2014 Aug 12.

PMID:
25127677
11.

Germline transgenesis of the chordate Ciona intestinalis with hyperactive variants of sleeping beauty transposable element.

Hozumi A, Mita K, Miskey C, Mates L, Izsvak Z, Ivics Z, Satake H, Sasakura Y.

Dev Dyn. 2013 Jan;242(1):30-43. doi: 10.1002/dvdy.23891. Epub 2012 Nov 14.

12.

Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma.

Mann KM, Ward JM, Yew CC, Kovochich A, Dawson DW, Black MA, Brett BT, Sheetz TE, Dupuy AJ; Australian Pancreatic Cancer Genome Initiative, Chang DK, Biankin AV, Waddell N, Kassahn KS, Grimmond SM, Rust AG, Adams DJ, Jenkins NA, Copeland NG.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):5934-41. doi: 10.1073/pnas.1202490109. Epub 2012 Mar 15.

14.

Prolonged expression of a lysosomal enzyme in mouse liver after Sleeping Beauty transposon-mediated gene delivery: implications for non-viral gene therapy of mucopolysaccharidoses.

Aronovich EL, Bell JB, Belur LR, Gunther R, Koniar B, Erickson DC, Schachern PA, Matise I, McIvor RS, Whitley CB, Hackett PB.

J Gene Med. 2007 May;9(5):403-15.

15.

Liver-directed gene therapy using the sleeping beauty transposon system.

Belur LR, McIvor RS, Wilber A.

Methods Mol Biol. 2008;434:267-76. doi: 10.1007/978-1-60327-248-3_16.

PMID:
18470650
16.

Stable gene transfer and expression in human primary T cells by the Sleeping Beauty transposon system.

Huang X, Wilber AC, Bao L, Tuong D, Tolar J, Orchard PJ, Levine BL, June CH, McIvor RS, Blazar BR, Zhou X.

Blood. 2006 Jan 15;107(2):483-91. Epub 2005 Sep 27.

17.

The Sleeping Beauty transposon toolbox.

Ammar I, Izsvák Z, Ivics Z.

Methods Mol Biol. 2012;859:229-40. doi: 10.1007/978-1-61779-603-6_13. Review.

PMID:
22367875
18.

Phenotypic correction and long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon system.

Ohlfest JR, Frandsen JL, Fritz S, Lobitz PD, Perkinson SG, Clark KJ, Nelsestuen G, Key NS, McIvor RS, Hackett PB, Largaespada DA.

Blood. 2005 Apr 1;105(7):2691-8. Epub 2004 Dec 2.

19.

Stable transgene expression in primitive human CD34+ hematopoietic stem/progenitor cells, using the Sleeping Beauty transposon system.

Sumiyoshi T, Holt NG, Hollis RP, Ge S, Cannon PM, Crooks GM, Kohn DB.

Hum Gene Ther. 2009 Dec;20(12):1607-26. doi: 10.1089/hum.2009.109.

20.

A novel method for somatic transgenesis of the mouse prostate using the Sleeping Beauty transposon system.

Hammer KD, Alsop JD, Buresh-Stiemke RA, Frantskevich K, Malinowski RL, Roethe LS, Powers GL, Marker PC.

Prostate. 2014 May;74(7):781-91. doi: 10.1002/pros.22797. Epub 2014 Mar 20.

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