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Items: 1 to 20 of 97


Recruitment of CD34(+) fibroblasts in tumor-associated reactive stroma: the reactive microvasculature hypothesis.

San Martin R, Barron DA, Tuxhorn JA, Ressler SJ, Hayward SW, Shen X, Laucirica R, Wheeler TM, Gutierrez C, Ayala GE, Ittmann M, Rowley DR.

Am J Pathol. 2014 Jun;184(6):1860-70. doi: 10.1016/j.ajpath.2014.02.021. Epub 2014 Apr 5.


Reactive stroma in the prostate during late life: The role of microvasculature and antiangiogenic therapy influences.

Montico F, Kido LA, San Martin R, Rowley DR, Cagnon VH.

Prostate. 2015 Oct;75(14):1643-61. doi: 10.1002/pros.23045. Epub 2015 Jul 17.


Reactive stroma in prostate cancer progression.

Tuxhorn JA, Ayala GE, Rowley DR.

J Urol. 2001 Dec;166(6):2472-83. Review.


The reactive stroma microenvironment and prostate cancer progression.

Barron DA, Rowley DR.

Endocr Relat Cancer. 2012 Oct 30;19(6):R187-204. doi: 10.1530/ERC-12-0085. Print 2012 Dec. Review.


Reactive stroma in human prostate cancer: induction of myofibroblast phenotype and extracellular matrix remodeling.

Tuxhorn JA, Ayala GE, Smith MJ, Smith VC, Dang TD, Rowley DR.

Clin Cancer Res. 2002 Sep;8(9):2912-23.


Elevated epithelial expression of interleukin-8 correlates with myofibroblast reactive stroma in benign prostatic hyperplasia.

Schauer IG, Ressler SJ, Tuxhorn JA, Dang TD, Rowley DR.

Urology. 2008 Jul;72(1):205-13. doi: 10.1016/j.urology.2007.11.083. Epub 2008 Mar 7.


Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts.

Trimmer C, Sotgia F, Whitaker-Menezes D, Balliet RM, Eaton G, Martinez-Outschoorn UE, Pavlides S, Howell A, Iozzo RV, Pestell RG, Scherer PE, Capozza F, Lisanti MP.

Cancer Biol Ther. 2011 Feb 15;11(4):383-94. Epub 2011 Feb 15.


Investigation of the origin of stromal and endothelial cells at the desmoplastic interface in xenograft tumor in mice.

Jung M, Ryu YJ, Kang G.

Pathol Res Pract. 2015 Dec;211(12):925-30. doi: 10.1016/j.prp.2015.09.005. Epub 2015 Oct 9.


Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples.

Gravina GL, Mancini A, Ranieri G, Di Pasquale B, Marampon F, Di Clemente L, Ricevuto E, Festuccia C.

Int J Oncol. 2013 Jun;42(6):2116-22. doi: 10.3892/ijo.2013.1892. Epub 2013 Apr 10.


Cigarette smoke metabolically promotes cancer, via autophagy and premature aging in the host stromal microenvironment.

Salem AF, Al-Zoubi MS, Whitaker-Menezes D, Martinez-Outschoorn UE, Lamb R, Hulit J, Howell A, Gandara R, Sartini M, Galbiati F, Bevilacqua G, Sotgia F, Lisanti MP.

Cell Cycle. 2013 Mar 1;12(5):818-25. doi: 10.4161/cc.23722. Epub 2013 Feb 6.


A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer-associated fibroblasts in human prostate cancer.

Clark AK, Taubenberger AV, Taylor RA, Niranjan B, Chea ZY, Zotenko E, Sieh S, Pedersen JS, Norden S, Frydenberg M, Grummet JP, Pook DW; Australian Prostate Cancer BioResource, Stirzaker C, Clark SJ, Lawrence MG, Ellem SJ, Hutmacher DW, Risbridger GP.

Biomaterials. 2013 Jul;34(20):4777-85. doi: 10.1016/j.biomaterials.2013.03.005. Epub 2013 Apr 2.


In vivo and in vitro characterization of human fibroblasts recruited selectively into human cancer stroma.

Ishii G, Sangai T, Ito T, Hasebe T, Endoh Y, Sasaki H, Harigaya K, Ochiai A.

Int J Cancer. 2005 Nov 1;117(2):212-20.


Stromal cells promote angiogenesis and growth of human prostate tumors in a differential reactive stroma (DRS) xenograft model.

Tuxhorn JA, McAlhany SJ, Dang TD, Ayala GE, Rowley DR.

Cancer Res. 2002 Jun 1;62(11):3298-307.


CD34+ fibrocytes in invasive ductal carcinoma, ductal carcinoma in situ, and benign breast lesions.

Barth PJ, Ebrahimsade S, Ramaswamy A, Moll R.

Virchows Arch. 2002 Mar;440(3):298-303. Epub 2001 Nov 22.


Genes upregulated in prostate cancer reactive stroma promote prostate cancer progression in vivo.

Dakhova O, Rowley D, Ittmann M.

Clin Cancer Res. 2014 Jan 1;20(1):100-9. doi: 10.1158/1078-0432.CCR-13-1184. Epub 2013 Oct 22.


Stromal expression of connective tissue growth factor promotes angiogenesis and prostate cancer tumorigenesis.

Yang F, Tuxhorn JA, Ressler SJ, McAlhany SJ, Dang TD, Rowley DR.

Cancer Res. 2005 Oct 1;65(19):8887-95.


Creating a tumor-resistant microenvironment: cell-mediated delivery of TNF╬▒ completely prevents breast cancer tumor formation in vivo.

Al-Zoubi M, Salem AF, Martinez-Outschoorn UE, Whitaker-Menezes D, Lamb R, Hulit J, Howell A, Gandara R, Sartini M, Arafat H, Bevilacqua G, Sotgia F, Lisanti MP.

Cell Cycle. 2013 Feb 1;12(3):480-90. doi: 10.4161/cc.23370. Epub 2012 Feb 1.


The role of fibroblast Tiam1 in tumor cell invasion and metastasis.

Xu K, Rajagopal S, Klebba I, Dong S, Ji Y, Liu J, Kuperwasser C, Garlick JA, Naber SP, Buchsbaum RJ.

Oncogene. 2010 Dec 16;29(50):6533-42. doi: 10.1038/onc.2010.385. Epub 2010 Aug 30.


Stromal-epithelial metabolic coupling in cancer: integrating autophagy and metabolism in the tumor microenvironment.

Martinez-Outschoorn UE, Pavlides S, Howell A, Pestell RG, Tanowitz HB, Sotgia F, Lisanti MP.

Int J Biochem Cell Biol. 2011 Jul;43(7):1045-51. doi: 10.1016/j.biocel.2011.01.023. Epub 2011 Feb 15. Review.


Keratinocyte-derived chemokine induces prostate epithelial hyperplasia and reactive stroma in a novel transgenic mouse model.

Schauer IG, Ressler SJ, Rowley DR.

Prostate. 2009 Mar 1;69(4):373-84. doi: 10.1002/pros.20886.

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