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Items: 1 to 20 of 100

1.

proNGF/NGF mixtures induce gene expression changes in PC12 cells that neither singly produces.

Arisi I, D'Onofrio M, Brandi R, Malerba F, Paoletti F, Storti AE, Florenzano F, Fasulo L, Cattaneo A.

BMC Neurosci. 2014 Apr 8;15:48. doi: 10.1186/1471-2202-15-48.

2.

NGF and proNGF regulate functionally distinct mRNAs in PC12 cells: an early gene expression profiling.

D'Onofrio M, Paoletti F, Arisi I, Brandi R, Malerba F, Fasulo L, Cattaneo A.

PLoS One. 2011;6(6):e20839. doi: 10.1371/journal.pone.0020839. Epub 2011 Jun 3.

3.

The nerve growth factor precursor proNGF exhibits neurotrophic activity but is less active than mature nerve growth factor.

Fahnestock M, Yu G, Michalski B, Mathew S, Colquhoun A, Ross GM, Coughlin MD.

J Neurochem. 2004 May;89(3):581-92.

4.

Biological activity of nerve growth factor precursor is dependent upon relative levels of its receptors.

Masoudi R, Ioannou MS, Coughlin MD, Pagadala P, Neet KE, Clewes O, Allen SJ, Dawbarn D, Fahnestock M.

J Biol Chem. 2009 Jul 3;284(27):18424-33. doi: 10.1074/jbc.M109.007104. Epub 2009 Apr 23.

5.

Intrinsic structural disorder of mouse proNGF.

Paoletti F, Covaceuszach S, Konarev PV, Gonfloni S, Malerba F, Schwarz E, Svergun DI, Cattaneo A, Lamba D.

Proteins. 2009 Jun;75(4):990-1009. doi: 10.1002/prot.22311.

PMID:
19089979
6.

Human ProNGF: biological effects and binding profiles at TrkA, P75NTR and sortilin.

Clewes O, Fahey MS, Tyler SJ, Watson JJ, Seok H, Catania C, Cho K, Dawbarn D, Allen SJ.

J Neurochem. 2008 Nov;107(4):1124-35. doi: 10.1111/j.1471-4159.2008.05698.x. Epub 2008 Sep 21.

7.
8.

ProNGF, sortilin, and age-related neurodegeneration.

Al-Shawi R, Hafner A, Chun S, Raza S, Crutcher K, Thrasivoulou C, Simons P, Cowen T.

Ann N Y Acad Sci. 2007 Nov;1119:208-15. Review.

PMID:
18056969
9.

ProNGF inhibits NGF-mediated TrkA activation in PC12 cells.

Sobottka B, Reinhardt D, Brockhaus M, Jacobsen H, Metzger F.

J Neurochem. 2008 Dec;107(5):1294-303. doi: 10.1111/j.1471-4159.2008.05690.x. Epub 2008 Sep 15.

10.

Molecular and structural insight into proNGF engagement of p75NTR and sortilin.

Feng D, Kim T, Ozkan E, Light M, Torkin R, Teng KK, Hempstead BL, Garcia KC.

J Mol Biol. 2010 Mar 5;396(4):967-84. doi: 10.1016/j.jmb.2009.12.030. Epub 2009 Dec 28.

11.

Nerve growth factor R221W responsible for insensitivity to pain is defectively processed and accumulates as proNGF.

Larsson E, Kuma R, Norberg A, Minde J, Holmberg M.

Neurobiol Dis. 2009 Feb;33(2):221-8. doi: 10.1016/j.nbd.2008.10.012. Epub 2008 Nov 8.

PMID:
19038341
12.

The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease.

Fahnestock M, Michalski B, Xu B, Coughlin MD.

Mol Cell Neurosci. 2001 Aug;18(2):210-20.

PMID:
11520181
13.

Construction of a mutated pro-nerve growth factor resistant to degradation and suitable for biophysical and cellular utilization.

Pagadala PC, Dvorak LA, Neet KE.

Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17939-43. Epub 2006 Nov 8.

14.

Neurotrophic activity of proNGF in vivo.

Buttigieg H, Kawaja MD, Fahnestock M.

Exp Neurol. 2007 Apr;204(2):832-5. Epub 2006 Dec 20.

PMID:
17270174
15.

ProNGF: a neurotrophic or an apoptotic molecule?

Fahnestock M, Yu G, Coughlin MD.

Prog Brain Res. 2004;146:101-10.

PMID:
14699959
16.

Nerve growth factor and proNGF simultaneously promote symmetric self-renewal, quiescence, and epithelial to mesenchymal transition to enlarge the breast cancer stem cell compartment.

Tomellini E, Touil Y, Lagadec C, Julien S, Ostyn P, Ziental-Gelus N, Meignan S, Lengrand J, Adriaenssens E, Polakowska R, Le Bourhis X.

Stem Cells. 2015 Feb;33(2):342-53. doi: 10.1002/stem.1849.

17.

Pro-nerve growth factor in the ovary and human granulosa cells.

Meinel S, Blohberger J, Berg D, Berg U, Dissen GA, Ojeda SR, Mayerhofer A.

Horm Mol Biol Clin Investig. 2015 Nov;24(2):91-9. doi: 10.1515/hmbci-2015-0028.

PMID:
26457789
18.

Neurotrophic actions initiated by proNGF in adult sensory neurons may require peri-somatic glia to drive local cleavage to NGF.

Kalous A, Nangle MR, Anastasia A, Hempstead BL, Keast JR.

J Neurochem. 2012 Aug;122(3):523-36. doi: 10.1111/j.1471-4159.2012.07799.x. Epub 2012 Jun 12.

19.

Expression of nerve growth factor (NGF) isoforms in the rat uterus during pregnancy: accumulation of precursor proNGF.

Lobos E, Gebhardt C, Kluge A, Spanel-Borowski K.

Endocrinology. 2005 Apr;146(4):1922-9. Epub 2005 Jan 6.

PMID:
15637294
20.

Proprotein convertase furin enhances survival and migration of vascular smooth muscle cells via processing of pro-nerve growth factor.

Urban D, Lorenz J, Meyborg H, Ghosh S, Kintscher U, Kaufmann J, Fleck E, Kappert K, Stawowy P.

J Biochem. 2013 Feb;153(2):197-207. doi: 10.1093/jb/mvs137. Epub 2012 Nov 21.

PMID:
23172302
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