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Items: 1 to 20 of 101

1.

β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.

Halban PA, Polonsky KS, Bowden DW, Hawkins MA, Ling C, Mather KJ, Powers AC, Rhodes CJ, Sussel L, Weir GC.

J Clin Endocrinol Metab. 2014 Jun;99(6):1983-92. doi: 10.1210/jc.2014-1425. Epub 2014 Apr 8.

2.

β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.

Halban PA, Polonsky KS, Bowden DW, Hawkins MA, Ling C, Mather KJ, Powers AC, Rhodes CJ, Sussel L, Weir GC.

Diabetes Care. 2014 Jun;37(6):1751-8. doi: 10.2337/dc14-0396. Epub 2014 May 8. Review.

3.

Natural history of β-cell adaptation and failure in type 2 diabetes.

Alejandro EU, Gregg B, Blandino-Rosano M, Cras-Méneur C, Bernal-Mizrachi E.

Mol Aspects Med. 2015 Apr;42:19-41. doi: 10.1016/j.mam.2014.12.002. Epub 2014 Dec 24. Review.

4.

Obesity and type 2 diabetes: what can be unified and what needs to be individualized?

Eckel RH, Kahn SE, Ferrannini E, Goldfine AB, Nathan DM, Schwartz MW, Smith RJ, Smith SR; Endocrine Society; American Diabetes Association; European Association for the Study of Diabetes.

Diabetes Care. 2011 Jun;34(6):1424-30. doi: 10.2337/dc11-0447. Epub 2011 May 20.

5.

Role of pancreatic β-cell death and inflammation in diabetes.

Quan W, Jo EK, Lee MS.

Diabetes Obes Metab. 2013 Sep;15 Suppl 3:141-51. doi: 10.1111/dom.12153. Review.

PMID:
24003931
6.

[Endoplasmic reticulum stress: from physiology to pathogenesis of type 2 diabetes].

Flamment M, Foufelle F.

Med Sci (Paris). 2013 Aug-Sep;29(8-9):756-64. doi: 10.1051/medsci/2013298015. Epub 2013 Sep 5. Review. French.

7.

Modulation of the pancreatic islet-stress axis as a novel potential therapeutic target in diabetes mellitus.

Ludwig B, Barthel A, Reichel A, Block NL, Ludwig S, Schally AV, Bornstein SR.

Vitam Horm. 2014;95:195-222. doi: 10.1016/B978-0-12-800174-5.00008-9. Review.

PMID:
24559919
8.

Endoplasmic reticulum stress in the β-cell pathogenesis of type 2 diabetes.

Back SH, Kang SW, Han J, Chung HT.

Exp Diabetes Res. 2012;2012:618396. doi: 10.1155/2012/618396. Epub 2011 Sep 8. Review.

9.

Death and dysfunction of transplanted β-cells: lessons learned from type 2 diabetes?

Potter KJ, Westwell-Roper CY, Klimek-Abercrombie AM, Warnock GL, Verchere CB.

Diabetes. 2014 Jan;63(1):12-9. doi: 10.2337/db12-0364. Review.

10.

Targeting beta-cell function early in the course of therapy for type 2 diabetes mellitus.

Leahy JL, Hirsch IB, Peterson KA, Schneider D.

J Clin Endocrinol Metab. 2010 Sep;95(9):4206-16. doi: 10.1210/jc.2010-0668. Epub 2010 Aug 25. Review.

PMID:
20739389
11.

Does disruption of circadian rhythms contribute to beta-cell failure in type 2 diabetes?

Rakshit K, Thomas AP, Matveyenko AV.

Curr Diab Rep. 2014 Apr;14(4):474. doi: 10.1007/s11892-014-0474-4. Review.

12.

Endoplasmic reticulum stress and type 2 diabetes.

Back SH, Kaufman RJ.

Annu Rev Biochem. 2012;81:767-93. doi: 10.1146/annurev-biochem-072909-095555. Epub 2012 Mar 23. Review.

13.

Oxidative stress, nitric oxide, and diabetes.

Pitocco D, Zaccardi F, Di Stasio E, Romitelli F, Santini SA, Zuppi C, Ghirlanda G.

Rev Diabet Stud. 2010 Spring;7(1):15-25. doi: 10.1900/RDS.2010.7.15. Epub 2010 May 10. Review.

14.

Oxidative and endoplasmic reticulum stress in β-cell dysfunction in diabetes.

Hasnain SZ, Prins JB, McGuckin MA.

J Mol Endocrinol. 2016 Feb;56(2):R33-54. doi: 10.1530/JME-15-0232. Epub 2015 Nov 17. Review.

PMID:
26576641
15.

Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure.

Talchai C, Xuan S, Lin HV, Sussel L, Accili D.

Cell. 2012 Sep 14;150(6):1223-34. doi: 10.1016/j.cell.2012.07.029.

16.

Genetic and biochemical pathways of beta-cell failure in type 2 diabetes.

Talchai C, Lin HV, Kitamura T, Accili D.

Diabetes Obes Metab. 2009 Nov;11 Suppl 4:38-45. doi: 10.1111/j.1463-1326.2009.01115.x. Review.

PMID:
19817787
17.

Epigenetic modifiers of islet function and mass.

De Jesus DF, Kulkarni RN.

Trends Endocrinol Metab. 2014 Dec;25(12):628-36. doi: 10.1016/j.tem.2014.08.006. Epub 2014 Sep 19. Review.

PMID:
25246382
18.

The role of FOXO1 in β-cell failure and type 2 diabetes mellitus.

Kitamura T.

Nat Rev Endocrinol. 2013 Oct;9(10):615-23. doi: 10.1038/nrendo.2013.157. Epub 2013 Aug 20. Review.

PMID:
23959366
19.

The pancreatic beta cells in human type 2 diabetes.

Marchetti P, Bugliani M, Boggi U, Masini M, Marselli L.

Adv Exp Med Biol. 2012;771:288-309. Review.

PMID:
23393686
20.

Epigenetics: the missing link to understanding β-cell dysfunction in the pathogenesis of type 2 diabetes.

Gilbert ER, Liu D.

Epigenetics. 2012 Aug;7(8):841-52. doi: 10.4161/epi.21238. Epub 2012 Jul 19. Review.

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