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Items: 1 to 20 of 90


Metabolomics approach to serum biomarker for loperamide-induced constipation in SD rats.

Kim JE, Lee YJ, Kwak MH, Jun G, Koh EK, Song SH, Seong JE, Kim JW, Kim KB, Kim S, Hwang DY.

Lab Anim Res. 2014 Mar;30(1):35-43. doi: 10.5625/lar.2014.30.1.35. Epub 2014 Mar 24.


Aqueous extracts of Liriope platyphylla induced significant laxative effects on loperamide-induced constipation of SD rats.

Kim JE, Lee YJ, Kwak MH, Ko J, Hong JT, Hwang DY.

BMC Complement Altern Med. 2013 Nov 26;13:333. doi: 10.1186/1472-6882-13-333.


Gallotannin-Enriched Extract Isolated from Galla Rhois May Be a Functional Candidate with Laxative Effects for Treatment of Loperamide-Induced Constipation of SD Rats.

Kim JE, Go J, Koh EK, Song SH, Sung JE, Lee HA, Lee YH, Hong JT, Hwang DY.

PLoS One. 2016 Sep 12;11(9):e0161144. doi: 10.1371/journal.pone.0161144. eCollection 2016.


Toxicometabolomics approach to urinary biomarkers for mercuric chloride (HgCl₂)-induced nephrotoxicity using proton nuclear magnetic resonance (¹H NMR) in rats.

Kim KB, Um SY, Chung MW, Jung SC, Oh JS, Kim SH, Na HS, Lee BM, Choi KH.

Toxicol Appl Pharmacol. 2010 Dec 1;249(2):114-26. doi: 10.1016/j.taap.2010.08.017. Epub 2010 Sep 9.


Uridine stimulate laxative effect in the loperamide-induced constipation of SD rats through regulation of the mAChRs signaling pathway and mucin secretion.

Kim JE, Go J, Sung JE, Lee HA, Yun WB, Hong JT, Hwang DY.

BMC Gastroenterol. 2017 Jan 26;17(1):21. doi: 10.1186/s12876-017-0576-y.


Characterization the response of Korl:ICR mice to loperamide induced constipation.

Kim JE, Yun WB, Sung JE, Lee HA, Choi JY, Choi YS, Jung YS, Kim KS, Hwang DY.

Lab Anim Res. 2016 Dec;32(4):231-240. doi: 10.5625/lar.2016.32.4.231. Epub 2016 Dec 23.


Cactus (Opuntia humifusa) water extract ameliorates loperamide-induced constipation in rats.

Han SH, Park K, Kim EY, Ahn SH, Lee HS, Suh HJ.

BMC Complement Altern Med. 2017 Jan 17;17(1):49. doi: 10.1186/s12906-016-1552-8.


Pattern recognition analysis for hepatotoxicity induced by acetaminophen using plasma and urinary 1H NMR-based metabolomics in humans.

Kim JW, Ryu SH, Kim S, Lee HW, Lim MS, Seong SJ, Kim S, Yoon YR, Kim KB.

Anal Chem. 2013 Dec 3;85(23):11326-34. doi: 10.1021/ac402390q. Epub 2013 Nov 14.


Decreased colonic mucus in rats with loperamide-induced constipation.

Shimotoyodome A, Meguro S, Hase T, Tokimitsu I, Sakata T.

Comp Biochem Physiol A Mol Integr Physiol. 2000 Jun;126(2):203-12.


Characterization of Changes in Global Genes Expression in the Distal Colon of Loperamide-Induced Constipation SD Rats in Response to the Laxative Effects of Liriope platyphylla.

Kim JE, Park SH, Kwak MH, Go J, Koh EK, Song SH, Sung JE, Lee HS, Hong JT, Hwang DY.

PLoS One. 2015 Jul 7;10(7):e0129664. doi: 10.1371/journal.pone.0129664. eCollection 2015.


Effects of Ficus carica paste on loperamide-induced constipation in rats.

Lee HY, Kim JH, Jeung HW, Lee CU, Kim DS, Li B, Lee GH, Sung MS, Ha KC, Back HI, Kim SY, Park SH, Oh MR, Kim MG, Jeon JY, Im YJ, Hwang MH, So BO, Shin SJ, Yoo WH, Kim HR, Chae HJ, Chae SW.

Food Chem Toxicol. 2012 Mar;50(3-4):895-902. doi: 10.1016/j.fct.2011.12.001. Epub 2011 Dec 9.


Laxative effects of Liriope platyphylla are tightly correlated with suppression of endoplasmic reticulum stress in loperamide-induced constipation of SD rats.

Kim JE, Go J, Sung JE, Lee HA, Seo EJ, Yun WB, Hwang DY.

Lab Anim Res. 2016 Mar;32(1):16-23. doi: 10.5625/lar.2016.32.1.16. Epub 2016 Mar 24.


Dynamic analysis of the endogenous metabolites in depressed patients treated with TCM formula Xiaoyaosan using urinary (1)H NMR-based metabolomics.

Tian JS, Peng GJ, Gao XX, Zhou YZ, Xing J, Qin XM, Du GH.

J Ethnopharmacol. 2014 Dec 2;158 Pt A:1-10. doi: 10.1016/j.jep.2014.10.005. Epub 2014 Oct 15.


Metabolomics approach to risk assessment: methoxyclor exposure in rats.

Kim KB, Kim SH, Um SY, Chung MW, Oh JS, Jung SC, Kim TS, Moon HJ, Han SY, Oh HY, Lee BM, Choi KH.

J Toxicol Environ Health A. 2009;72(21-22):1352-68. doi: 10.1080/15287390903212550.


Combination of ¹H NMR- and GC-MS-based metabonomics to study on the toxicity of Coptidis Rhizome in rats.

Zhou Y, Liao Q, Lin M, Deng X, Zhang P, Yao M, Zhang L, Xie Z.

PLoS One. 2014 Feb 5;9(2):e88281. doi: 10.1371/journal.pone.0088281. eCollection 2014.


Constipation enhances the propensity to seizure in pentylenetetrazole-induced seizure models of mice.

Moezi L, Pirsalami F, Inaloo S.

Epilepsy Behav. 2015 Mar;44:200-6. doi: 10.1016/j.yebeh.2015.01.013. Epub 2015 Mar 6.


Metabolic profiling of kidney and urine in rats with lithium-induced nephrogenic diabetes insipidus by (1)H-NMR-based metabonomics.

Hwang GS, Yang JY, Ryu DH, Kwon TH.

Am J Physiol Renal Physiol. 2010 Feb;298(2):F461-70. doi: 10.1152/ajprenal.00389.2009. Epub 2009 Nov 18.


Hepatotoxic constituents and toxicological mechanism of Xanthium strumarium L. fruits.

Xue LM, Zhang QY, Han P, Jiang YP, Yan RD, Wang Y, Rahman K, Jia M, Han T, Qin LP.

J Ethnopharmacol. 2014 Mar 14;152(2):272-82. doi: 10.1016/j.jep.2013.12.024. Epub 2014 Jan 18.


Effect of colic vein ligature in rats with loperamide-induced constipation.

Neri F, Cavallari G, Tsivian M, Bianchi E, Aldini R, Cevenini M, Guidetti E, Piras GL, Pariali M, Nardo B.

J Biomed Biotechnol. 2012;2012:896162. doi: 10.1155/2012/896162. Epub 2012 May 8.


Nuclear magnetic resonance-based metabolomics for prediction of gastric damage induced by indomethacin in rats.

Um SY, Park JH, Chung MW, Kim KB, Kim SH, Choi KH, Lee HJ.

Anal Chim Acta. 2012 Apr 13;722:87-94. doi: 10.1016/j.aca.2012.01.062. Epub 2012 Feb 13.


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