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Items: 1 to 20 of 123

1.

Twist-related protein 1 negatively regulated osteoblastic transdifferentiation of human aortic valve interstitial cells by directly inhibiting runt-related transcription factor 2.

Zhang XW, Zhang BY, Wang SW, Gong DJ, Han L, Xu ZY, Liu XH.

J Thorac Cardiovasc Surg. 2014 Oct;148(4):1700-1708.e1. doi: 10.1016/j.jtcvs.2014.02.084. Epub 2014 Mar 4.

PMID:
24703637
2.

MicroRNA-204 Targets Runx2 to Attenuate BMP-2-induced Osteoblast Differentiation of Human Aortic Valve Interstitial Cells.

Wang Y, Chen S, Deng C, Li F, Wang Y, Hu X, Shi F, Dong N.

J Cardiovasc Pharmacol. 2015 Jul;66(1):63-71. doi: 10.1097/FJC.0000000000000244.

PMID:
25806689
3.

Bone morphogenic protein 2 induces Runx2 and osteopontin expression in human aortic valve interstitial cells: role of Smad1 and extracellular signal-regulated kinase 1/2.

Yang X, Meng X, Su X, Mauchley DC, Ao L, Cleveland JC Jr, Fullerton DA.

J Thorac Cardiovasc Surg. 2009 Oct;138(4):1008-15. doi: 10.1016/j.jtcvs.2009.06.024. Epub 2009 Aug 6.

4.

Apelin attenuates the osteoblastic differentiation of aortic valve interstitial cells via the ERK and PI3-K/Akt pathways.

Yuan ZS, Zhou YZ, Liao XB, Luo JW, Shen KJ, Hu YR, Gu L, Li JM, Tan CM, Chen HM, Zhou XM.

Amino Acids. 2015 Dec;47(12):2475-82. doi: 10.1007/s00726-015-2020-3. Epub 2015 Jul 5.

5.

Endoplasmic reticulum stress participates in aortic valve calcification in hypercholesterolemic animals.

Cai Z, Li F, Gong W, Liu W, Duan Q, Chen C, Ni L, Xia Y, Cianflone K, Dong N, Wang DW.

Arterioscler Thromb Vasc Biol. 2013 Oct;33(10):2345-54. doi: 10.1161/ATVBAHA.112.300226. Epub 2013 Aug 8.

6.

MicroRNA-30b is a multifunctional regulator of aortic valve interstitial cells.

Zhang M, Liu X, Zhang X, Song Z, Han L, He Y, Xu Z.

J Thorac Cardiovasc Surg. 2014 Mar;147(3):1073-1080.e2. doi: 10.1016/j.jtcvs.2013.05.011. Epub 2013 Aug 19.

7.

Osteopontin-CD44v6 interaction mediates calcium deposition via phospho-Akt in valve interstitial cells from patients with noncalcified aortic valve sclerosis.

Poggio P, Branchetti E, Grau JB, Lai EK, Gorman RC, Gorman JH 3rd, Sacks MS, Bavaria JE, Ferrari G.

Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):2086-94. doi: 10.1161/ATVBAHA.113.303017. Epub 2014 Jul 24.

8.

miRNA-141 is a novel regulator of BMP-2-mediated calcification in aortic stenosis.

Yanagawa B, Lovren F, Pan Y, Garg V, Quan A, Tang G, Singh KK, Shukla PC, Kalra NP, Peterson MD, Verma S.

J Thorac Cardiovasc Surg. 2012 Jul;144(1):256-62. doi: 10.1016/j.jtcvs.2011.10.097. Epub 2012 Feb 14.

9.

Valvular osteoclasts in calcification and aortic valve stenosis severity.

Nagy E, Eriksson P, Yousry M, Caidahl K, Ingelsson E, Hansson GK, Franco-Cereceda A, Bäck M.

Int J Cardiol. 2013 Oct 3;168(3):2264-71. doi: 10.1016/j.ijcard.2013.01.207. Epub 2013 Feb 27.

10.

Expression of smooth muscle cell markers and co-activators in calcified aortic valves.

Latif N, Sarathchandra P, Chester AH, Yacoub MH.

Eur Heart J. 2015 Jun 1;36(21):1335-45. doi: 10.1093/eurheartj/eht547. Epub 2014 Jan 12.

PMID:
24419809
11.

Antioxidant enzymes reduce DNA damage and early activation of valvular interstitial cells in aortic valve sclerosis.

Branchetti E, Sainger R, Poggio P, Grau JB, Patterson-Fortin J, Bavaria JE, Chorny M, Lai E, Gorman RC, Levy RJ, Ferrari G.

Arterioscler Thromb Vasc Biol. 2013 Feb;33(2):e66-74. doi: 10.1161/ATVBAHA.112.300177. Epub 2012 Dec 13. Erratum in: Arterioscler Thromb Vasc Biol. 2013 May;33(5):e115.

12.

Noggin attenuates the osteogenic activation of human valve interstitial cells in aortic valve sclerosis.

Poggio P, Sainger R, Branchetti E, Grau JB, Lai EK, Gorman RC, Sacks MS, Parolari A, Bavaria JE, Ferrari G.

Cardiovasc Res. 2013 Jun 1;98(3):402-10. doi: 10.1093/cvr/cvt055. Epub 2013 Mar 12.

13.

Calcification by valve interstitial cells is regulated by the stiffness of the extracellular matrix.

Yip CY, Chen JH, Zhao R, Simmons CA.

Arterioscler Thromb Vasc Biol. 2009 Jun;29(6):936-42. doi: 10.1161/ATVBAHA.108.182394. Epub 2009 Mar 19.

14.

The expression of groups IIE and V phospholipase A2 is associated with an increased expression of osteogenic molecules in human calcified aortic valves.

Suzuki K, Takahashi S, Watanabe K, Fujioka D, Nakamura T, Obata JE, Kawabata K, Katoh R, Matsumoto M, Kugiyama K.

J Atheroscler Thromb. 2014;21(12):1308-25. Epub 2014 Aug 15.

15.

Osteopontin alters endothelial and valvular interstitial cell behaviour in calcific aortic valve stenosis through HMGB1 regulation.

Passmore M, Nataatmadja M, Fung YL, Pearse B, Gabriel S, Tesar P, Fraser JF.

Eur J Cardiothorac Surg. 2015 Sep;48(3):e20-9. doi: 10.1093/ejcts/ezv244.

PMID:
26273067
16.

Calcium Signaling Pathway Genes RUNX2 and CACNA1C Are Associated With Calcific Aortic Valve Disease.

Guauque-Olarte S, Messika-Zeitoun D, Droit A, Lamontagne M, Tremblay-Marchand J, Lavoie-Charland E, Gaudreault N, Arsenault BJ, Dubé MP, Tardif JC, Body SC, Seidman JG, Boileau C, Mathieu P, Pibarot P, Bossé Y.

Circ Cardiovasc Genet. 2015 Dec;8(6):812-22. doi: 10.1161/CIRCGENETICS.115.001145. Epub 2015 Nov 9.

17.

Comparison of calcification potential of valvular interstitial cells isolated from individual aortic valve cusps.

Masjedi S, Amarnath A, Baily KM, Ferdous Z.

Cardiovasc Pathol. 2016 May-Jun;25(3):185-94. doi: 10.1016/j.carpath.2015.12.002. Epub 2015 Dec 30.

PMID:
26874039
18.

The basic helix loop helix transcription factor Twist1 is a novel regulator of ATF4 in osteoblasts.

Danciu TE, Li Y, Koh A, Xiao G, McCauley LK, Franceschi RT.

J Cell Biochem. 2012 Jan;113(1):70-9. doi: 10.1002/jcb.23329.

19.

Twist1 promotes heart valve cell proliferation and extracellular matrix gene expression during development in vivo and is expressed in human diseased aortic valves.

Chakraborty S, Wirrig EE, Hinton RB, Merrill WH, Spicer DB, Yutzey KE.

Dev Biol. 2010 Nov 1;347(1):167-79. doi: 10.1016/j.ydbio.2010.08.021. Epub 2010 Sep 6.

20.

Role of Wnt/β-catenin signaling pathway in the mechanism of calcification of aortic valve.

Gu GJ, Chen T, Zhou HM, Sun KX, Li J.

J Huazhong Univ Sci Technolog Med Sci. 2014 Feb;34(1):33-6. doi: 10.1007/s11596-014-1228-x. Epub 2014 Feb 6.

PMID:
24496676

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