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Items: 1 to 20 of 116

1.

Multisite phosphorylation of C-Nap1 releases it from Cep135 to trigger centrosome disjunction.

Hardy T, Lee M, Hames RS, Prosser SL, Cheary DM, Samant MD, Schultz F, Baxter JE, Rhee K, Fry AM.

J Cell Sci. 2014 Jun 1;127(Pt 11):2493-506. doi: 10.1242/jcs.142331. Epub 2014 Apr 2.

2.

The centrosomal linker and microtubules provide dual levels of spatial coordination of centrosomes.

Panic M, Hata S, Neuner A, Schiebel E.

PLoS Genet. 2015 May 22;11(5):e1005243. doi: 10.1371/journal.pgen.1005243. eCollection 2015 May.

3.

The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles.

Mayor T, Hacker U, Stierhof YD, Nigg EA.

J Cell Sci. 2002 Aug 15;115(Pt 16):3275-84.

4.

Rootletin forms centriole-associated filaments and functions in centrosome cohesion.

Bahe S, Stierhof YD, Wilkinson CJ, Leiss F, Nigg EA.

J Cell Biol. 2005 Oct 10;171(1):27-33. Epub 2005 Oct 3.

5.

Nek2A kinase stimulates centrosome disjunction and is required for formation of bipolar mitotic spindles.

Faragher AJ, Fry AM.

Mol Biol Cell. 2003 Jul;14(7):2876-89. Epub 2003 Apr 17.

6.

beta-Catenin is a Nek2 substrate involved in centrosome separation.

Bahmanyar S, Kaplan DD, Deluca JG, Giddings TH Jr, O'Toole ET, Winey M, Salmon ED, Casey PJ, Nelson WJ, Barth AI.

Genes Dev. 2008 Jan 1;22(1):91-105. Epub 2007 Dec 17.

7.

Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction.

Mardin BR, Lange C, Baxter JE, Hardy T, Scholz SR, Fry AM, Schiebel E.

Nat Cell Biol. 2010 Dec;12(12):1166-76. doi: 10.1038/ncb2120. Epub 2010 Nov 14.

8.

LRRC45 is a centrosome linker component required for centrosome cohesion.

He R, Huang N, Bao Y, Zhou H, Teng J, Chen J.

Cell Rep. 2013 Sep 26;4(6):1100-7. doi: 10.1016/j.celrep.2013.08.005. Epub 2013 Sep 12.

9.

A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization.

Kim K, Lee S, Chang J, Rhee K.

Exp Cell Res. 2008 Dec 10;314(20):3692-700. doi: 10.1016/j.yexcr.2008.09.016. Epub 2008 Oct 1.

PMID:
18851962
10.

Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion.

Fang G, Zhang D, Yin H, Zheng L, Bi X, Yuan L.

J Cell Sci. 2014 Apr 15;127(Pt 8):1631-9. doi: 10.1242/jcs.139451. Epub 2014 Feb 19.

11.

C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2.

Fry AM, Mayor T, Meraldi P, Stierhof YD, Tanaka K, Nigg EA.

J Cell Biol. 1998 Jun 29;141(7):1563-74.

12.

The tumor suppressor proteins ASPP1 and ASPP2 interact with C-Nap1 and regulate centrosome linker reassembly.

Zhang Y, Wang Y, Wei Y, Ma J, Peng J, Wumaier R, Shen S, Zhang P, Yu L.

Biochem Biophys Res Commun. 2015 Mar 13;458(3):494-500. doi: 10.1016/j.bbrc.2015.01.136. Epub 2015 Feb 7.

PMID:
25660448
13.

Plk1 controls the Nek2A-PP1γ antagonism in centrosome disjunction.

Mardin BR, Agircan FG, Lange C, Schiebel E.

Curr Biol. 2011 Jul 12;21(13):1145-51. doi: 10.1016/j.cub.2011.05.047. Epub 2011 Jun 30.

14.

Cep68 can be regulated by Nek2 and SCF complex.

Man X, Megraw TL, Lim YP.

Eur J Cell Biol. 2015 Mar-Apr;94(3-4):162-72. doi: 10.1016/j.ejcb.2015.01.004. Epub 2015 Feb 4.

PMID:
25704143
15.

Nip2/centrobin may be a substrate of Nek2 that is required for proper spindle assembly during mitosis in early mouse embryos.

Sonn S, Jeong Y, Rhee K.

Mol Reprod Dev. 2009 Jun;76(6):587-92. doi: 10.1002/mrd.20990.

PMID:
19117032
16.

Nek2 and its substrate, centrobin/Nip2, are required for proper meiotic spindle formation of the mouse oocytes.

Sonn S, Oh GT, Rhee K.

Zygote. 2011 Feb;19(1):15-20. doi: 10.1017/S0967199410000183. Epub 2010 Jun 23.

PMID:
20569513
17.

Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion.

Graser S, Stierhof YD, Nigg EA.

J Cell Sci. 2007 Dec 15;120(Pt 24):4321-31. Epub 2007 Nov 27.

18.

Nek2 phosphorylates and stabilizes β-catenin at mitotic centrosomes downstream of Plk1.

Mbom BC, Siemers KA, Ostrowski MA, Nelson WJ, Barth AI.

Mol Biol Cell. 2014 Apr;25(7):977-91. doi: 10.1091/mbc.E13-06-0349. Epub 2014 Feb 5.

19.

Characterization of Cep85 - a new antagonist of Nek2A that is involved in the regulation of centrosome disjunction.

Chen C, Tian F, Lu L, Wang Y, Xiao Z, Yu C, Yu X.

J Cell Sci. 2015 Sep 1;128(17):3290-303. doi: 10.1242/jcs.171637. Epub 2015 Jul 28. Erratum in: J Cell Sci. 2015 Oct 15;128(20):3837.

20.

The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion.

Mayor T, Stierhof YD, Tanaka K, Fry AM, Nigg EA.

J Cell Biol. 2000 Nov 13;151(4):837-46.

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