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Items: 1 to 20 of 99

1.

Dual role of acetaminophen in promoting hepatoma cell apoptosis and kidney fibroblast proliferation.

Yu YL, Yiang GT, Chou PL, Tseng HH, Wu TK, Hung YT, Lin PS, Lin SY, Liu HC, Chang WJ, Wei CW.

Mol Med Rep. 2014 Jun;9(6):2077-84. doi: 10.3892/mmr.2014.2085. Epub 2014 Mar 28.

2.

Acetaminophen induces JNK/p38 signaling and activates the caspase-9-3-dependent cell death pathway in human mesenchymal stem cells.

Yiang GT, Yu YL, Lin KT, Chen JN, Chang WJ, Wei CW.

Int J Mol Med. 2015 Aug;36(2):485-92. doi: 10.3892/ijmm.2015.2254. Epub 2015 Jun 19.

3.

Taurine protects acetaminophen-induced oxidative damage in mice kidney through APAP urinary excretion and CYP2E1 inactivation.

Das J, Ghosh J, Manna P, Sil PC.

Toxicology. 2010 Feb 28;269(1):24-34. doi: 10.1016/j.tox.2010.01.003. Epub 2010 Jan 11.

PMID:
20067817
4.

Comparative evaluation of N-acetylcysteine and N-acetylcysteineamide in acetaminophen-induced hepatotoxicity in human hepatoma HepaRG cells.

Tobwala S, Khayyat A, Fan W, Ercal N.

Exp Biol Med (Maywood). 2015 Feb;240(2):261-72. doi: 10.1177/1535370214549520. Epub 2014 Sep 21.

5.

Increased mitochondrial stress and modulation of mitochondrial respiratory enzyme activities in acetaminophen-induced toxicity in mouse macrophage cells.

Al-Belooshi T, John A, Tariq S, Al-Otaiba A, Raza H.

Food Chem Toxicol. 2010 Oct;48(10):2624-32. doi: 10.1016/j.fct.2010.06.031. Epub 2010 Jun 22.

PMID:
20600533
6.

Hesperidin alleviates acetaminophen induced toxicity in Wistar rats by abrogation of oxidative stress, apoptosis and inflammation.

Ahmad ST, Arjumand W, Nafees S, Seth A, Ali N, Rashid S, Sultana S.

Toxicol Lett. 2012 Jan 25;208(2):149-61. doi: 10.1016/j.toxlet.2011.10.023. Epub 2011 Nov 7.

PMID:
22093918
7.

Effects of administration of subtoxic doses of acetaminophen on liver and blood levels of insulin-like growth factor-1 in rats.

Ozdemir D, Aksu I, Baykara B, Ates M, Sisman AR, Kiray M, Buyuk A, Uysal N.

Toxicol Ind Health. 2016 Jan;32(1):39-46. doi: 10.1177/0748233713498439. Epub 2013 Aug 1.

PMID:
23907830
8.

Differential Cytotoxicity of Acetaminophen in Mouse Macrophage J774.2 and Human Hepatoma HepG2 Cells: Protection by Diallyl Sulfide.

Raza H, John A.

PLoS One. 2015 Dec 29;10(12):e0145965. doi: 10.1371/journal.pone.0145965. eCollection 2015.

9.

rhIL-1Ra reduces hepatocellular apoptosis in mice with acetaminophen-induced acute liver failure.

Hu J, Yan D, Gao J, Xu C, Yuan Y, Zhu R, Xiang D, Weng S, Han W, Zang G, Yu Y.

Lab Invest. 2010 Dec;90(12):1737-46. doi: 10.1038/labinvest.2010.127. Epub 2010 Jul 19.

10.

Arsanilic acid causes apoptosis and oxidative stress in rat kidney epithelial cells (NRK-52e cells) by the activation of the caspase-9 and -3 signaling pathway.

Lu Y, Yuan H, Deng S, Wei Q, Guo C, Yi J, Wu J, Li R, Wen L, He Z, Yuan L.

Drug Chem Toxicol. 2014 Jan;37(1):55-62. doi: 10.3109/01480545.2013.806532. Epub 2013 Jul 12.

PMID:
23848144
11.
12.

Role of caspase-1 and interleukin-1beta in acetaminophen-induced hepatic inflammation and liver injury.

Williams CD, Farhood A, Jaeschke H.

Toxicol Appl Pharmacol. 2010 Sep 15;247(3):169-78. doi: 10.1016/j.taap.2010.07.004. Epub 2010 Jul 15.

13.
14.

Arjunolic acid, a triterpenoid saponin, prevents acetaminophen (APAP)-induced liver and hepatocyte injury via the inhibition of APAP bioactivation and JNK-mediated mitochondrial protection.

Ghosh J, Das J, Manna P, Sil PC.

Free Radic Biol Med. 2010 Feb 15;48(4):535-53. doi: 10.1016/j.freeradbiomed.2009.11.023. Epub 2009 Dec 4.

PMID:
19969075
15.

Thearubigins protect against acetaminophen-induced hepatic and renal injury in mice: biochemical, histopathological, immunohistochemical, and flow cytometry study.

Murad HA, Habib H, Kamel Y, Alsayed S, Shakweer M, Elshal M.

Drug Chem Toxicol. 2016;39(2):190-8. doi: 10.3109/01480545.2015.1070170. Epub 2015 Aug 3.

PMID:
26234406
16.

Octreotide induces caspase activation and apoptosis in human hepatoma HepG2 cells.

Tsagarakis NJ, Drygiannakis I, Batistakis AG, Kolios G, Kouroumalis EA.

World J Gastroenterol. 2011 Jan 21;17(3):313-21. doi: 10.3748/wjg.v17.i3.313.

17.

The potential protective role of alpha-lipoic acid against acetaminophen-induced hepatic and renal damage.

Abdel-Zaher AO, Abdel-Hady RH, Mahmoud MM, Farrag MM.

Toxicology. 2008 Jan 20;243(3):261-70. Epub 2007 Oct 23.

PMID:
18068886
18.
19.

Mouse strain-dependent caspase activation during acetaminophen hepatotoxicity does not result in apoptosis or modulation of inflammation.

Williams CD, Koerner MR, Lampe JN, Farhood A, Jaeschke H.

Toxicol Appl Pharmacol. 2011 Dec 15;257(3):449-58. doi: 10.1016/j.taap.2011.10.006. Epub 2011 Oct 14.

20.

Combined treatment with vitamin E and gefitinib has synergistic effects to inhibit TGF-β1-induced renal fibroblast proliferation.

Yiang GT, Chen JN, Lin PS, Liu HC, Chen SY, Wei CW.

Mol Med Rep. 2016 Jun;13(6):5372-8. doi: 10.3892/mmr.2016.5155. Epub 2016 Apr 21.

PMID:
27109695

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