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Pharmacological mobilization of endogenous stem cells significantly promotes skin regeneration after full-thickness excision: the synergistic activity of AMD3100 and tacrolimus.

Lin Q, Wesson RN, Maeda H, Wang Y, Cui Z, Liu JO, Cameron AM, Gao B, Montgomery RA, Williams GM, Sun Z.

J Invest Dermatol. 2014 Sep;134(9):2458-68. doi: 10.1038/jid.2014.162. Epub 2014 Mar 28.


Augmentation of cutaneous wound healing by pharmacologic mobilization of endogenous bone marrow stem cells.

Tolar J, McGrath JA.

J Invest Dermatol. 2014 Sep;134(9):2312-4. doi: 10.1038/jid.2014.209.


Adult stem cell mobilization enhances intramembranous bone regeneration: a pilot study.

McNulty MA, Virdi AS, Christopherson KW, Sena K, Frank RR, Sumner DR.

Clin Orthop Relat Res. 2012 Sep;470(9):2503-12. doi: 10.1007/s11999-012-2357-9.


Mobilization of endogenous stem cell populations enhances fracture healing in a murine femoral fracture model.

Toupadakis CA, Granick JL, Sagy M, Wong A, Ghassemi E, Chung DJ, Borjesson DL, Yellowley CE.

Cytotherapy. 2013 Sep;15(9):1136-47. doi: 10.1016/j.jcyt.2013.05.004. Epub 2013 Jul 3.


Cells to surgery quiz: September 2014.

Griffith RD, Falto-Aizpurua L, Yazdani Abyaneh MA, Nouri K.

J Invest Dermatol. 2014 Sep;134(9):e5. doi: 10.1038/jid.2014.279. No abstract available.


Mobilization of bone marrow mesenchymal stem cells in vivo augments bone healing in a mouse model of segmental bone defect.

Kumar S, Ponnazhagan S.

Bone. 2012 Apr;50(4):1012-8. doi: 10.1016/j.bone.2012.01.027. Epub 2012 Feb 9.


Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells.

Dar A, Schajnovitz A, Lapid K, Kalinkovich A, Itkin T, Ludin A, Kao WM, Battista M, Tesio M, Kollet O, Cohen NN, Margalit R, Buss EC, Baleux F, Oishi S, Fujii N, Larochelle A, Dunbar CE, Broxmeyer HE, Frenette PS, Lapidot T.

Leukemia. 2011 Aug;25(8):1286-96. doi: 10.1038/leu.2011.62. Epub 2011 Apr 15. Erratum in: Leukemia. 2011 Aug;25(8):1378.


AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates.

Larochelle A, Krouse A, Metzger M, Orlic D, Donahue RE, Fricker S, Bridger G, Dunbar CE, Hematti P.

Blood. 2006 May 1;107(9):3772-8. Epub 2006 Jan 26.


Insights into the biology of mobilized hematopoietic stem/progenitor cells through innovative treatment schedules of the CXCR4 antagonist AMD3100.

Bonig H, Chudziak D, Priestley G, Papayannopoulou T.

Exp Hematol. 2009 Mar;37(3):402-15.e1. doi: 10.1016/j.exphem.2008.10.017. Epub 2009 Jan 20.


CXC-chemokine receptor 4 antagonist AMD3100 promotes cardiac functional recovery after ischemia/reperfusion injury via endothelial nitric oxide synthase-dependent mechanism.

Jujo K, Ii M, Sekiguchi H, Klyachko E, Misener S, Tanaka T, Tongers J, Roncalli J, Renault MA, Thorne T, Ito A, Clarke T, Kamide C, Tsurumi Y, Hagiwara N, Qin G, Asahi M, Losordo DW.

Circulation. 2013 Jan 1;127(1):63-73. doi: 10.1161/CIRCULATIONAHA.112.099242. Epub 2012 Nov 30.


Parathyroid hormone is a DPP-IV inhibitor and increases SDF-1-driven homing of CXCR4(+) stem cells into the ischaemic heart.

Huber BC, Brunner S, Segeth A, Nathan P, Fischer R, Zaruba MM, Vallaster M, Theiss HD, David R, Gerbitz A, Franz WM.

Cardiovasc Res. 2011 Jun 1;90(3):529-37. doi: 10.1093/cvr/cvr014. Epub 2011 Jan 18.


Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist.

Broxmeyer HE, Orschell CM, Clapp DW, Hangoc G, Cooper S, Plett PA, Liles WC, Li X, Graham-Evans B, Campbell TB, Calandra G, Bridger G, Dale DC, Srour EF.

J Exp Med. 2005 Apr 18;201(8):1307-18.


Update on clinical experience with AMD3100, an SDF-1/CXCL12-CXCR4 inhibitor, in mobilization of hematopoietic stem and progenitor cells.

Pusic I, DiPersio JF.

Curr Opin Hematol. 2010 Jul;17(4):319-26. doi: 10.1097/MOH.0b013e328338b7d5. Review.


CXCR4 antagonist AMD3100 accelerates impaired wound healing in diabetic mice.

Nishimura Y, Ii M, Qin G, Hamada H, Asai J, Takenaka H, Sekiguchi H, Renault MA, Jujo K, Katoh N, Kishimoto S, Ito A, Kamide C, Kenny J, Millay M, Misener S, Thorne T, Losordo DW.

J Invest Dermatol. 2012 Mar;132(3 Pt 1):711-20. doi: 10.1038/jid.2011.356. Epub 2011 Nov 3.


Human progenitor cells rapidly mobilized by AMD3100 repopulate NOD/SCID mice with increased frequency in comparison to cells from the same donor mobilized by granulocyte colony stimulating factor.

Hess DA, Bonde J, Craft TP, Wirthlin L, Hohm S, Lahey R, Todt LM, Dipersio JF, Devine SM, Nolta JA.

Biol Blood Marrow Transplant. 2007 Apr;13(4):398-411. Erratum in: Biol Blood Marrow Transplant. 2007 Jun;13(6):747. Craft, Timothy C [corrected to Craft, Timothy P].


In and out of the niche: perspectives in mobilization of hematopoietic stem cells.

Mohty M, Ho AD.

Exp Hematol. 2011 Jul;39(7):723-9. doi: 10.1016/j.exphem.2011.05.004. Epub 2011 May 13. Review.


CXCR4-mediated bone marrow progenitor cell maintenance and mobilization are modulated by c-kit activity.

Cheng M, Zhou J, Wu M, Boriboun C, Thorne T, Liu T, Xiang Z, Zeng Q, Tanaka T, Tang YL, Kishore R, Tomasson MH, Miller RJ, Losordo DW, Qin G.

Circ Res. 2010 Oct 29;107(9):1083-93. doi: 10.1161/CIRCRESAHA.110.220970. Epub 2010 Sep 16.


Plerixafor, a CXCR4 antagonist for the mobilization of hematopoietic stem cells.

Uy GL, Rettig MP, Cashen AF.

Expert Opin Biol Ther. 2008 Nov;8(11):1797-804. doi: 10.1517/14712598.8.11.1797 . Review.


New agents for mobilizing peripheral blood stem cells.

Greinix HT, Worel N.

Transfus Apher Sci. 2009 Aug;41(1):67-71. doi: 10.1016/j.transci.2009.05.015. Epub 2009 Jul 16.


Effective mobilization of hematopoietic progenitor cells in G-CSF mobilization defective CD26-/- mice through AMD3100-induced disruption of the CXCL12-CXCR4 axis.

Paganessi LA, Walker AL, Tan LL, Holmes I, Rich E, Fung HC, Christopherson KW 2nd.

Exp Hematol. 2011 Mar;39(3):384-90. doi: 10.1016/j.exphem.2010.12.003. Epub 2010 Dec 17.

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