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Items: 1 to 20 of 112

1.

Constitutive activation of the ATM/BRCA1 pathway prevents DNA damage-induced apoptosis in 5-azacytidine-resistant cell lines.

Imanishi S, Umezu T, Ohtsuki K, Kobayashi C, Ohyashiki K, Ohyashiki JH.

Biochem Pharmacol. 2014 Jun 1;89(3):361-9. doi: 10.1016/j.bcp.2014.03.008. Epub 2014 Mar 26.

PMID:
24680865
2.

Cytotoxicity of 5-Aza-2'-deoxycytidine against gastric cancer involves DNA damage in an ATM-P53 dependent signaling pathway and demethylation of P16(INK4A).

Liu J, Xie YS, Wang FL, Zhang LJ, Zhang Y, Luo HS.

Biomed Pharmacother. 2013 Feb;67(1):78-87. doi: 10.1016/j.biopha.2012.10.015. Epub 2012 Nov 19.

PMID:
23201008
3.

Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation.

Reu FJ, Bae SI, Cherkassky L, Leaman DW, Lindner D, Beaulieu N, MacLeod AR, Borden EC.

J Clin Oncol. 2006 Aug 10;24(23):3771-9. Epub 2006 Jun 26.

PMID:
16801630
5.

5-Aza-2'-deoxycytidine induces cytotoxicity in BGC-823 cells via DNA methyltransferase 1 and 3a independent of p53 status.

Liu J, Zhang Y, Xie YS, Wang FL, Zhang LJ, Deng T, Luo HS.

Oncol Rep. 2012 Aug;28(2):545-52. doi: 10.3892/or.2012.1838. Epub 2012 May 29.

PMID:
22664909
7.

Combinations of DNA methyltransferase and histone deacetylase inhibitors induce DNA damage in small cell lung cancer cells: correlation of resistance with IFN-stimulated gene expression.

Luszczek W, Cheriyath V, Mekhail TM, Borden EC.

Mol Cancer Ther. 2010 Aug;9(8):2309-21. doi: 10.1158/1535-7163.MCT-10-0309. Epub 2010 Aug 3.

8.

Azacytidine and decitabine induce gene-specific and non-random DNA demethylation in human cancer cell lines.

Hagemann S, Heil O, Lyko F, Brueckner B.

PLoS One. 2011 Mar 7;6(3):e17388. doi: 10.1371/journal.pone.0017388.

10.

Tamoxifen enhances erlotinib-induced cytotoxicity through down-regulating AKT-mediated thymidine phosphorylase expression in human non-small-cell lung cancer cells.

Ko JC, Chiu HC, Syu JJ, Jian YJ, Chen CY, Jian YT, Huang YJ, Wo TY, Lin YW.

Biochem Pharmacol. 2014 Mar 1;88(1):119-27. doi: 10.1016/j.bcp.2014.01.010. Epub 2014 Jan 18.

PMID:
24447935
11.
12.

Expression analysis of genes involved in epigenetic regulation and apoptosis in human malignant haematopoietic cell lines treated with 5-azacytidine.

Stankov K, Bogdanovic G, Kojic V, Stankov S, Jojic N, Popovic L, Popovic S.

J BUON. 2011 Jan-Mar;16(1):116-22.

PMID:
21674861
13.

Effects of DNA methyltransferase inhibitors (DNMTIs) on MDS-derived cell lines.

Tsujioka T, Yokoi A, Uesugi M, Kishimoto M, Tochigi A, Suemori S, Tohyama Y, Tohyama K.

Exp Hematol. 2013 Feb;41(2):189-97. doi: 10.1016/j.exphem.2012.10.006. Epub 2012 Oct 17.

PMID:
23085465
14.
15.

Mechanisms of resistance to azacitidine in human leukemia cell lines.

Sripayap P, Nagai T, Uesawa M, Kobayashi H, Tsukahara T, Ohmine K, Muroi K, Ozawa K.

Exp Hematol. 2014 Apr;42(4):294-306.e2. doi: 10.1016/j.exphem.2013.12.004. Epub 2013 Dec 22.

PMID:
24368162
16.

Silencing HO-1 sensitizes SKM-1 cells to apoptosis induced by low concentration 5-azacytidine through enhancing p16 demethylation.

Wang P, Ma D, Wang J, Fang Q, Gao R, Wu W, Lu T, Cao L.

Int J Oncol. 2015 Mar;46(3):1317-27. doi: 10.3892/ijo.2015.2835. Epub 2015 Jan 12.

PMID:
25585641
17.

LW-214, a newly synthesized flavonoid, induces intrinsic apoptosis pathway by down-regulating Trx-1 in MCF-7 human breast cells.

Pan D, Li W, Miao H, Yao J, Li Z, Wei L, Zhao L, Guo Q.

Biochem Pharmacol. 2014 Feb 15;87(4):598-610. doi: 10.1016/j.bcp.2013.12.010. Epub 2013 Dec 27.

PMID:
24374359
18.

[Effect and mechanism of DNMT inhibitor on the reversal of multidrug resistance in human colon cancer cell line sw620/L-OHP].

Deng Q, Li ZP, Huang CM, Liu Z, Zhong RM, Li AJ, Bi F, Tang QL.

Sichuan Da Xue Xue Bao Yi Xue Ban. 2010 Nov;41(6):975-9. Chinese.

PMID:
21265097
19.

Methylation silencing of the Apaf-1 gene in acute leukemia.

Furukawa Y, Sutheesophon K, Wada T, Nishimura M, Saito Y, Ishii H, Furukawa Y.

Mol Cancer Res. 2005 Jun;3(6):325-34.

20.

Synergistic effect of 5-azacytidine and NF-κB inhibitor DHMEQ on apoptosis induction in myeloid leukemia cells.

Togano T, Nakashima M, Watanabe M, Umezawa K, Watanabe T, Higashihara M, Horie R.

Oncol Res. 2012;20(12):571-7. doi: 10.3727/096504013X13775486749371.

PMID:
24139415

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