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Items: 1 to 20 of 113

1.

U4 at the 3' UTR of PB1 segment of H5N1 influenza virus promotes RNA polymerase activity and contributes to viral pathogenicity.

Sun W, Li J, Han P, Yang Y, Kang X, Li Y, Li J, Zhang Y, Wu X, Jiang T, Qin C, Hu Y, Zhu Q.

PLoS One. 2014 Mar 27;9(3):e93366. doi: 10.1371/journal.pone.0093366. eCollection 2014.

2.

The PA-gene-mediated lethal dissemination and excessive innate immune response contribute to the high virulence of H5N1 avian influenza virus in mice.

Hu J, Hu Z, Song Q, Gu M, Liu X, Wang X, Hu S, Chen C, Liu H, Liu W, Chen S, Peng D, Liu X.

J Virol. 2013 Mar;87(5):2660-72. doi: 10.1128/JVI.02891-12. Epub 2012 Dec 19.

3.

Glycine at Position 622 in PB1 Contributes to the Virulence of H5N1 Avian Influenza Virus in Mice.

Feng X, Wang Z, Shi J, Deng G, Kong H, Tao S, Li C, Liu L, Guan Y, Chen H.

J Virol. 2015 Dec 9;90(4):1872-9. doi: 10.1128/JVI.02387-15.

4.

Amino acid substitutions in PB1 of avian influenza viruses influence pathogenicity and transmissibility in chickens.

Suzuki Y, Uchida Y, Tanikawa T, Maeda N, Takemae N, Saito T.

J Virol. 2014 Oct;88(19):11130-9. doi: 10.1128/JVI.01564-14. Epub 2014 Jul 16.

5.

Kinetic characterization of PB1-F2-mediated immunopathology during highly pathogenic avian H5N1 influenza virus infection.

Leymarie O, Jouvion G, Hervé PL, Chevalier C, Lorin V, Lecardonnel J, Da Costa B, Delmas B, Escriou N, Le Goffic R.

PLoS One. 2013;8(3):e57894. doi: 10.1371/journal.pone.0057894. Epub 2013 Mar 1.

6.

Host- and strain-specific regulation of influenza virus polymerase activity by interacting cellular proteins.

Bortz E, Westera L, Maamary J, Steel J, Albrecht RA, Manicassamy B, Chase G, Martínez-Sobrido L, Schwemmle M, García-Sastre A.

MBio. 2011 Aug 16;2(4). pii: e00151-11. doi: 10.1128/mBio.00151-11. Print 2011.

7.

Molecular signatures of virulence in the PB1-F2 proteins of H5N1 influenza viruses.

Smith AM, McCullers JA.

Virus Res. 2013 Dec 5;178(1):146-50. doi: 10.1016/j.virusres.2013.02.012. Epub 2013 Mar 14.

8.

Emergence of Highly Pathogenic Avian Influenza A(H5N1) Virus PB1-F2 Variants and Their Virulence in BALB/c Mice.

Kamal RP, Kumar A, Davis CT, Tzeng WP, Nguyen T, Donis RO, Katz JM, York IA.

J Virol. 2015 Jun;89(11):5835-46. doi: 10.1128/JVI.03137-14. Epub 2015 Mar 18.

9.

Reassortment between avian H5N1 and human H3N2 influenza viruses creates hybrid viruses with substantial virulence.

Li C, Hatta M, Nidom CA, Muramoto Y, Watanabe S, Neumann G, Kawaoka Y.

Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4687-92. doi: 10.1073/pnas.0912807107. Epub 2010 Feb 22.

10.

A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence.

Conenello GM, Zamarin D, Perrone LA, Tumpey T, Palese P.

PLoS Pathog. 2007 Oct 5;3(10):1414-21.

11.

PB1-mediated virulence attenuation of H5N1 influenza virus in mice is associated with PB2.

Li J, Li Y, Hu Y, Chang G, Sun W, Yang Y, Kang X, Wu X, Zhu Q.

J Gen Virol. 2011 Jun;92(Pt 6):1435-44. doi: 10.1099/vir.0.030718-0. Epub 2011 Mar 2.

PMID:
21367983
12.

Amino acids 473V and 598P of PB1 from an avian-origin influenza A virus contribute to polymerase activity, especially in mammalian cells.

Xu C, Hu WB, Xu K, He YX, Wang TY, Chen Z, Li TX, Liu JH, Buchy P, Sun B.

J Gen Virol. 2012 Mar;93(Pt 3):531-40. doi: 10.1099/vir.0.036434-0. Epub 2011 Nov 16.

PMID:
22090209
13.

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species.

Schmolke M, Manicassamy B, Pena L, Sutton T, Hai R, Varga ZT, Hale BG, Steel J, Pérez DR, García-Sastre A.

PLoS Pathog. 2011 Aug;7(8):e1002186. doi: 10.1371/journal.ppat.1002186. Epub 2011 Aug 11.

14.

Caspase-1 deficient mice are more susceptible to influenza A virus infection with PA variation.

Huang CH, Chen CJ, Yen CT, Yu CP, Huang PN, Kuo RL, Lin SJ, Chang CK, Shih SR.

J Infect Dis. 2013 Dec 1;208(11):1898-905. doi: 10.1093/infdis/jit381. Epub 2013 Jul 30.

PMID:
23901080
15.

NP body domain and PB2 contribute to increased virulence of H5N1 highly pathogenic avian influenza viruses in chickens.

Tada T, Suzuki K, Sakurai Y, Kubo M, Okada H, Itoh T, Tsukamoto K.

J Virol. 2011 Feb;85(4):1834-46. doi: 10.1128/JVI.01648-10. Epub 2010 Dec 1.

16.

Virulence and genetic compatibility of polymerase reassortant viruses derived from the pandemic (H1N1) 2009 influenza virus and circulating influenza A viruses.

Song MS, Pascua PN, Lee JH, Baek YH, Park KJ, Kwon HI, Park SJ, Kim CJ, Kim H, Webby RJ, Webster RG, Choi YK.

J Virol. 2011 Jul;85(13):6275-86. doi: 10.1128/JVI.02125-10. Epub 2011 Apr 20.

17.

Influenza A virus utilizes a suboptimal Kozak sequence to fine-tune virus replication and host response.

Wang J, Peng Y, Zhao L, Cao M, Hung T, Deng T.

J Gen Virol. 2015 Apr;96(Pt 4):756-66. doi: 10.1099/vir.0.000030. Epub 2014 Dec 17.

PMID:
25519170
18.

Virulence determinants of avian H5N1 influenza A virus in mammalian and avian hosts: role of the C-terminal ESEV motif in the viral NS1 protein.

Zielecki F, Semmler I, Kalthoff D, Voss D, Mauel S, Gruber AD, Beer M, Wolff T.

J Virol. 2010 Oct;84(20):10708-18. doi: 10.1128/JVI.00610-10. Epub 2010 Aug 4.

19.

Differential localization and function of PB1-F2 derived from different strains of influenza A virus.

Chen CJ, Chen GW, Wang CH, Huang CH, Wang YC, Shih SR.

J Virol. 2010 Oct;84(19):10051-62. doi: 10.1128/JVI.00592-10. Epub 2010 Jul 21.

20.

RNA interference of avian influenza virus H5N1 by inhibiting viral mRNA with siRNA expression plasmids.

Zhou K, He H, Wu Y, Duan M.

J Biotechnol. 2008 Jun 1;135(2):140-4. doi: 10.1016/j.jbiotec.2008.03.007. Epub 2008 Mar 26.

PMID:
18456361

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