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Items: 1 to 20 of 106

1.

Conformation and recognition of DNA damaged by antitumor cis-dichlorido platinum(II) complex of CDK inhibitor bohemine.

Novakova O, Liskova B, Vystrcilova J, Suchankova T, Vrana O, Starha P, Travnicek Z, Brabec V.

Eur J Med Chem. 2014 May 6;78:54-64. doi: 10.1016/j.ejmech.2014.03.041. Epub 2014 Mar 15.

PMID:
24675180
2.

Cellular response to antitumor cis-Dichlorido platinum(II) complexes of CDK inhibitor Bohemine and its analogues.

Liskova B, Zerzankova L, Novakova O, Kostrhunova H, Travnicek Z, Brabec V.

Chem Res Toxicol. 2012 Feb 20;25(2):500-9. doi: 10.1021/tx200525n. Epub 2012 Feb 1.

PMID:
22250642
4.

Activation of trans geometry in bifunctional mononuclear platinum complexes by a non-bulky methylamine ligand.

Frybortova M, Novakova O, Stepankova J, Novohradsky V, Gibson D, Kasparkova J, Brabec V.

J Inorg Biochem. 2013 Sep;126:46-54. doi: 10.1016/j.jinorgbio.2013.05.009. Epub 2013 May 28.

PMID:
23770803
5.

Energetics, conformation, and recognition of DNA duplexes containing a major adduct of an anticancer azolato-bridged dinuclear Pt(II) complex.

Mlcouskova J, Malina J, Novohradsky V, Kasparkova J, Komeda S, Brabec V.

Biochim Biophys Acta. 2012 Oct;1820(10):1502-11. doi: 10.1016/j.bbagen.2012.05.014. Epub 2012 Jun 7.

PMID:
22683702
6.

Replacement of a thiourea with an amidine group in a monofunctional platinum-acridine antitumor agent. Effect on DNA interactions, DNA adduct recognition and repair.

Kostrhunova H, Malina J, Pickard AJ, Stepankova J, Vojtiskova M, Kasparkova J, Muchova T, Rohlfing ML, Bierbach U, Brabec V.

Mol Pharm. 2011 Oct 3;8(5):1941-54. doi: 10.1021/mp200309x. Epub 2011 Aug 17.

7.

Multiple states of stalled T7 RNA polymerase at DNA lesions generated by platinum anticancer agents.

Jung Y, Lippard SJ.

J Biol Chem. 2003 Dec 26;278(52):52084-92. Epub 2003 Oct 8.

8.

DNA binding by antitumor trans-[PtCl2(NH3)(thiazole)]. Protein recognition and nucleotide excision repair of monofunctional adducts.

Kasparkova J, Novakova O, Farrell N, Brabec V.

Biochemistry. 2003 Jan 28;42(3):792-800.

PMID:
12534292
9.

cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects.

Lovejoy KS, Todd RC, Zhang S, McCormick MS, D'Aquino JA, Reardon JT, Sancar A, Giacomini KM, Lippard SJ.

Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):8902-7. doi: 10.1073/pnas.0803441105. Epub 2008 Jun 25.

11.

Preparation and characterization of platinum(II) and (IV) complexes of 1,3-diaminepropane and 1,4-diaminebutane: circumvention of cisplatin resistance and DNA interstrand cross-link formation in CH1cisR ovarian tumor cells.

Alvarez-Valdés A, Pérez JM, López-Solera I, Lannegrand R, Continente JM, Amo-Ochoa P, Camazón MJ, Solans X, Font-Bardía M, Navarro-Ranninger C.

J Med Chem. 2002 Apr 25;45(9):1835-44.

PMID:
11960495
12.

Different features of the DNA binding mode of antitumor cis-amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro.

Kostrhunova H, Vrana O, Suchankova T, Gibson D, Kasparkova J, Brabec V.

Chem Res Toxicol. 2010 Nov 15;23(11):1833-42. doi: 10.1021/tx1002904. Epub 2010 Oct 12.

PMID:
20939593
13.

Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring Pt II chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand.

Kasparkova J, Suchankova T, Halamikova A, Zerzankova L, Vrana O, Margiotta N, Natile G, Brabec V.

Biochem Pharmacol. 2010 Feb 15;79(4):552-64. doi: 10.1016/j.bcp.2009.09.019.

PMID:
19782655
14.
17.
18.

Inversion of the cis geometry requirement for cytotoxicity in structurally novel platinum(II) complexes containing the bidentate N,O-donor pyridin-2-yl-acetate.

Bierbach U, Sabat M, Farrell N.

Inorg Chem. 2000 May 1;39(9):1882-90. Erratum in: Inorg Chem 2000 Jun 26;39(13):2960.

PMID:
11428108
19.

DNA conformation and repair of polymeric natural DNA damaged by antitumor azolato-bridged dinuclear Pt(II) complex.

Mlcouskova J, Kasparkova J, Suchankova T, Komeda S, Brabec V.

J Inorg Biochem. 2012 Sep;114:15-23. doi: 10.1016/j.jinorgbio.2012.04.015. Epub 2012 May 4.

PMID:
22687561
20.

DNA interactions of a novel platinum drug, cis-[PtCl(NH3)2(N7-acyclovir)]+.

Balcarová Z, Kaspárková J, Zákovská A, Nováková O, Sivo MF, Natile G, Brabec V.

Mol Pharmacol. 1998 May;53(5):846-55.

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