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Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.

Nielsen N, Pascal V, Fasth AE, Sundström Y, Galsgaard ED, Ahern D, Andersen M, Baslund B, Bartels EM, Bliddal H, Feldmann M, Malmström V, Berg L, Spee P, Söderström K.

Immunology. 2014 Aug;142(4):581-93. doi: 10.1111/imm.12271.


Influence of in vitro IL-2 or IL-15 alone or in combination with Hsp-70-derived 14-mer peptide (TKD) on the expression of NK cell activatory and inhibitory receptors.

Hromadnikova I, Pirkova P, Sedlackova L.

Mediators Inflamm. 2013;2013:405295. doi: 10.1155/2013/405295. Epub 2013 Feb 17.


Interleukin-22 Secreted by NKp44+ Natural Killer Cells Promotes Proliferation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis.

Zhu J, Jia E, Zhou Y, Xu J, Feng Z, Wang H, Chen X, Li J.

Medicine (Baltimore). 2015 Dec;94(52):e2137. doi: 10.1097/MD.0000000000002137.


Inhibitory NKG2A and activating NKG2D and NKG2C natural killer cell receptor genes: susceptibility for rheumatoid arthritis.

Park KS, Park JH, Song YW.

Tissue Antigens. 2008 Oct;72(4):342-6. doi: 10.1111/j.1399-0039.2008.01110.x. Epub 2008 Aug 12.


Activating and inhibitory receptors on synovial fluid natural killer cells of arthritis patients: role of CD94/NKG2A in control of cytokine secretion.

de Matos CT, Berg L, Michaëlsson J, Felländer-Tsai L, Kärre K, Söderström K.

Immunology. 2007 Oct;122(2):291-301. Epub 2007 May 22.


NKp46 and DNAM-1 NK-cell receptors drive the response to human cytomegalovirus-infected myeloid dendritic cells overcoming viral immune evasion strategies.

Magri G, Muntasell A, Romo N, Sáez-Borderías A, Pende D, Geraghty DE, Hengel H, Angulo A, Moretta A, López-Botet M.

Blood. 2011 Jan 20;117(3):848-56. doi: 10.1182/blood-2010-08-301374. Epub 2010 Oct 28.


Overexpression of CD158 and NKG2A Inhibitory Receptors and Underexpression of NKG2D and NKp46 Activating Receptors on NK Cells in Acute Myeloid Leukemia.

Sandoval-Borrego D, Moreno-Lafont MC, Vazquez-Sanchez EA, Gutierrez-Hoya A, López-Santiago R, Montiel-Cervantes LA, Ramírez-Saldaña M, Vela-Ojeda J.

Arch Med Res. 2016 Jan;47(1):55-64. doi: 10.1016/j.arcmed.2016.02.001. Epub 2016 Feb 12.


Differential expression of NK receptors CD94 and NKG2A by T cells in rheumatoid arthritis patients in remission compared to active disease.

Walsh CE, Ryan EJ, O'Farrelly C, Golden-Mason L, FitzGerald O, Veale DJ, Bresnihan B, Fearon U.

PLoS One. 2011;6(11):e27182. doi: 10.1371/journal.pone.0027182. Epub 2011 Nov 15.


Minimal requirement for induction of natural cytotoxicity and intersection of activation signals by inhibitory receptors.

Bryceson YT, Ljunggren HG, Long EO.

Blood. 2009 Sep 24;114(13):2657-66. doi: 10.1182/blood-2009-01-201632. Epub 2009 Jul 23.


Short-term exposure to human cytomegalovirus-infected fibroblasts induces a proportional increase of active CD94/NKG2A(+) natural killer cells.

Petersen L, Petersen CC, Møller-Larsen A, Hokland ME.

Hum Immunol. 2010 Jan;71(1):29-35. doi: 10.1016/j.humimm.2009.09.355.


A rapid method for assessment of natural killer cell function after multiple receptor crosslinking.

Al-Hubeshy ZB, Coleman A, Nelson M, Goodier MR.

J Immunol Methods. 2011 Mar 7;366(1-2):52-9. doi: 10.1016/j.jim.2011.01.007. Epub 2011 Jan 28. Erratum in: J Immunol Methods. 2011 Oct 28;373(1-2):252.


Synergistic inhibition of natural killer cells by the nonsignaling molecule CD94.

Cheent KS, Jamil KM, Cassidy S, Liu M, Mbiribindi B, Mulder A, Claas FH, Purbhoo MA, Khakoo SI.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16981-6. doi: 10.1073/pnas.1304366110. Epub 2013 Sep 30.


The natural killer cell-mediated killing of autologous dendritic cells is confined to a cell subset expressing CD94/NKG2A, but lacking inhibitory killer Ig-like receptors.

Della Chiesa M, Vitale M, Carlomagno S, Ferlazzo G, Moretta L, Moretta A.

Eur J Immunol. 2003 Jun;33(6):1657-66. Erratum in: Eur J Immunol. 2003 Oct;33(10):2947.


Role of NKG2D, DNAM-1 and natural cytotoxicity receptors in cytotoxicity toward rhabdomyosarcoma cell lines mediated by resting and IL-15-activated human natural killer cells.

Boerman GH, van Ostaijen-ten Dam MM, Kraal KC, Santos SJ, Ball LM, Lankester AC, Schilham MW, Egeler RM, van Tol MJ.

Cancer Immunol Immunother. 2015 May;64(5):573-83. doi: 10.1007/s00262-015-1657-9. Epub 2015 Feb 18.


The effect of mifepristone on the peripheral blood natural killer cell's cytotoxicity and expression of CD94/NKG2A and NKG2D during the implantation phase.

Chen XY, Zhuang YL, Li L, Zhang WW, Huang LL.

Fertil Steril. 2010 May 15;93(8):2615-20. doi: 10.1016/j.fertnstert.2009.09.015. Epub 2009 Nov 2.


Regulatory role of NKp44, NKp46, DNAM-1 and NKG2D receptors in the interaction between NK cells and trophoblast cells. Evidence for divergent functional profiles of decidual versus peripheral NK cells.

Vacca P, Cantoni C, Prato C, Fulcheri E, Moretta A, Moretta L, Mingari MC.

Int Immunol. 2008 Nov;20(11):1395-405. doi: 10.1093/intimm/dxn105. Epub 2008 Sep 23.


Synergistic signals for natural cytotoxicity are required to overcome inhibition by c-Cbl ubiquitin ligase.

Kim HS, Das A, Gross CC, Bryceson YT, Long EO.

Immunity. 2010 Feb 26;32(2):175-86. doi: 10.1016/j.immuni.2010.02.004.

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