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Items: 1 to 20 of 109

1.

NOD2 downregulates colonic inflammation by IRF4-mediated inhibition of K63-linked polyubiquitination of RICK and TRAF6.

Watanabe T, Asano N, Meng G, Yamashita K, Arai Y, Sakurai T, Kudo M, Fuss IJ, Kitani A, Shimosegawa T, Chiba T, Strober W.

Mucosal Immunol. 2014 Nov;7(6):1312-25. doi: 10.1038/mi.2014.19. Epub 2014 Mar 26.

2.

NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2.

Yang Y, Yin C, Pandey A, Abbott D, Sassetti C, Kelliher MA.

J Biol Chem. 2007 Dec 14;282(50):36223-9. Epub 2007 Oct 18.

3.

Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis.

Watanabe T, Asano N, Murray PJ, Ozato K, Tailor P, Fuss IJ, Kitani A, Strober W.

J Clin Invest. 2008 Feb;118(2):545-59. doi: 10.1172/JCI33145.

4.

Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains.

Abbott DW, Yang Y, Hutti JE, Madhavarapu S, Kelliher MA, Cantley LC.

Mol Cell Biol. 2007 Sep;27(17):6012-25. Epub 2007 Jun 11.

5.

A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation.

Hasegawa M, Fujimoto Y, Lucas PC, Nakano H, Fukase K, Núñez G, Inohara N.

EMBO J. 2008 Jan 23;27(2):373-83. Epub 2007 Dec 13.

6.

Nucleotide-binding oligomerization domain containing 2: structure, function, and diseases.

Yao Q.

Semin Arthritis Rheum. 2013 Aug;43(1):125-30. doi: 10.1016/j.semarthrit.2012.12.005. Epub 2013 Jan 24. Review.

PMID:
23352252
7.

The molecular basis of NOD2 susceptibility mutations in Crohn's disease.

Strober W, Kitani A, Fuss I, Asano N, Watanabe T.

Mucosal Immunol. 2008 Nov;1 Suppl 1:S5-9. doi: 10.1038/mi.2008.42. Review.

8.

Differential effect of vitamin D on NOD2- and TLR-induced cytokines in Crohn's disease.

Dionne S, Calderon MR, White JH, Memari B, Elimrani I, Adelson B, Piccirillo C, Seidman EG.

Mucosal Immunol. 2014 Nov;7(6):1405-15. doi: 10.1038/mi.2014.30. Epub 2014 Apr 30.

PMID:
24781050
9.

The NOD2-RICK complex signals from the plasma membrane.

Lécine P, Esmiol S, Métais JY, Nicoletti C, Nourry C, McDonald C, Nunez G, Hugot JP, Borg JP, Ollendorff V.

J Biol Chem. 2007 May 18;282(20):15197-207. Epub 2007 Mar 13.

10.

Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease.

van Heel DA, Ghosh S, Hunt KA, Mathew CG, Forbes A, Jewell DP, Playford RJ.

Gut. 2005 Nov;54(11):1553-7. Epub 2005 May 31.

11.
12.

Human umbilical cord blood mesenchymal stem cells reduce colitis in mice by activating NOD2 signaling to COX2.

Kim HS, Shin TH, Lee BC, Yu KR, Seo Y, Lee S, Seo MS, Hong IS, Choi SW, Seo KW, Núñez G, Park JH, Kang KS.

Gastroenterology. 2013 Dec;145(6):1392-403.e1-8. doi: 10.1053/j.gastro.2013.08.033. Epub 2013 Aug 21.

PMID:
23973922
13.

Cellular and molecular mechanisms underlying NOD2 risk-associated polymorphisms in Crohn's disease.

Strober W, Asano N, Fuss I, Kitani A, Watanabe T.

Immunol Rev. 2014 Jul;260(1):249-60. doi: 10.1111/imr.12193. Review.

PMID:
24942694
14.

Genome-wide expression profiling identifies an impairment of negative feedback signals in the Crohn's disease-associated NOD2 variant L1007fsinsC.

Billmann-Born S, Till A, Arlt A, Lipinski S, Sina C, Latiano A, Annese V, Häsler R, Kerick M, Manke T, Seegert D, Hanidu A, Schäfer H, van Heel D, Li J, Schreiber S, Rosenstiel P.

J Immunol. 2011 Apr 1;186(7):4027-38. doi: 10.4049/jimmunol.1000085. Epub 2011 Feb 18.

15.

Dysregulated NOD2 predisposes SAMP1/YitFc mice to chronic intestinal inflammation.

Corridoni D, Kodani T, Rodriguez-Palacios A, Pizarro TT, Xin W, Nickerson KP, McDonald C, Ley KF, Abbott DW, Cominelli F.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16999-7004. doi: 10.1073/pnas.1311657110. Epub 2013 Sep 30.

16.

Control of NOD2 and Rip2-dependent innate immune activation by GEF-H1.

Zhao Y, Alonso C, Ballester I, Song JH, Chang SY, Guleng B, Arihiro S, Murray PJ, Xavier R, Kobayashi KS, Reinecker HC.

Inflamm Bowel Dis. 2012 Apr;18(4):603-12. doi: 10.1002/ibd.21851. Epub 2011 Sep 1.

17.

Toll-like receptor-induced granulocyte-macrophage colony-stimulating factor secretion is impaired in Crohn's disease by nucleotide oligomerization domain 2-dependent and -independent pathways.

Brosbøl-Ravnborg A, Hvas CL, Agnholt J, Dahlerup JF, Vind I, Till A, Rosenstiel P, Höllsberg P.

Clin Exp Immunol. 2009 Mar;155(3):487-95. doi: 10.1111/j.1365-2249.2008.03850.x. Epub 2008 Dec 15.

18.

Nod2 and Rip2 contribute to innate immune responses in mouse neutrophils.

Jeong YJ, Kang MJ, Lee SJ, Kim CH, Kim JC, Kim TH, Kim DJ, Kim D, Núñez G, Park JH.

Immunology. 2014 Oct;143(2):269-76. doi: 10.1111/imm.12307.

19.

Expression of TRAF6 and pro-inflammatory cytokines through activation of TLR2, TLR4, NOD1, and NOD2 in human periodontal ligament fibroblasts.

Tang L, Zhou XD, Wang Q, Zhang L, Wang Y, Li XY, Huang DM.

Arch Oral Biol. 2011 Oct;56(10):1064-72. doi: 10.1016/j.archoralbio.2011.02.020. Epub 2011 Mar 31.

PMID:
21457942
20.

NOD2 ligation subverts IFN-alpha production by liver plasmacytoid dendritic cells and inhibits their T cell allostimulatory activity via B7-H1 up-regulation.

Castellaneta A, Sumpter TL, Chen L, Tokita D, Thomson AW.

J Immunol. 2009 Dec 1;183(11):6922-32. doi: 10.4049/jimmunol.0900582. Epub 2009 Nov 4.

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