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Items: 1 to 20 of 129

1.

In vivo imaging of mGluR5 changes during epileptogenesis using [11C]ABP688 PET in pilocarpine-induced epilepsy rat model.

Choi H, Kim YK, Oh SW, Im HJ, Hwang DW, Kang H, Lee B, Lee YS, Jeong JM, Kim EE, Chung JK, Lee DS.

PLoS One. 2014 Mar 24;9(3):e92765. doi: 10.1371/journal.pone.0092765. eCollection 2014.

2.

N-acetylcysteine- and MK-801-induced changes in glutamate levels do not affect in vivo binding of metabotropic glutamate 5 receptor radioligand 11C-ABP688 in rat brain.

Wyckhuys T, Verhaeghe J, Wyffels L, Langlois X, Schmidt M, Stroobants S, Staelens S.

J Nucl Med. 2013 Nov;54(11):1954-61. doi: 10.2967/jnumed.113.121608. Epub 2013 Sep 19.

3.

Characterization of age/sex and the regional distribution of mGluR5 availability in the healthy human brain measured by high-resolution [(11)C]ABP688 PET.

DuBois JM, Rousset OG, Rowley J, Porras-Betancourt M, Reader AJ, Labbe A, Massarweh G, Soucy JP, Rosa-Neto P, Kobayashi E.

Eur J Nucl Med Mol Imaging. 2016 Jan;43(1):152-62. doi: 10.1007/s00259-015-3167-6. Epub 2015 Aug 21.

PMID:
26290423
4.

In vivo characterization of metabotropic glutamate receptor type 5 abnormalities in behavioral variant FTD.

Leuzy A, Zimmer ER, Dubois J, Pruessner J, Cooperman C, Soucy JP, Kostikov A, Schirmaccher E, Désautels R, Gauthier S, Rosa-Neto P.

Brain Struct Funct. 2016 Apr;221(3):1387-402. doi: 10.1007/s00429-014-0978-3. Epub 2015 Jan 18.

PMID:
25596865
5.

Changes in glucose metabolism and metabolites during the epileptogenic process in the lithium-pilocarpine model of epilepsy.

Lee EM, Park GY, Im KC, Kim ST, Woo CW, Chung JH, Kim KS, Kim JS, Shon YM, Kim YI, Kang JK.

Epilepsia. 2012 May;53(5):860-9. doi: 10.1111/j.1528-1167.2012.03432.x. Epub 2012 Mar 16.

6.

Radiosynthesis and preclinical evaluation of 11C-ABP688 as a probe for imaging the metabotropic glutamate receptor subtype 5.

Ametamey SM, Kessler LJ, Honer M, Wyss MT, Buck A, Hintermann S, Auberson YP, Gasparini F, Schubiger PA.

J Nucl Med. 2006 Apr;47(4):698-705.

7.

Circadian variation of metabotropic glutamate receptor 5 availability in the rat brain.

Elmenhorst D, Mertens K, Kroll T, Oskamp A, Ermert J, Elmenhorst EM, Wedekind F, Beer S, Coenen HH, Bauer A.

J Sleep Res. 2016 Dec;25(6):754-761. doi: 10.1111/jsr.12432. Epub 2016 Jun 30.

PMID:
27357735
8.

Limbic system mGluR5 availability in cocaine dependent subjects: a high-resolution PET [(11)C]ABP688 study.

Milella MS, Marengo L, Larcher K, Fotros A, Dagher A, Rosa-Neto P, Benkelfat C, Leyton M.

Neuroimage. 2014 Sep;98:195-202. doi: 10.1016/j.neuroimage.2014.04.061. Epub 2014 May 2.

PMID:
24795154
9.

Metabotropic Glutamate Receptor Type 5 (mGluR5) Cortical Abnormalities in Focal Cortical Dysplasia Identified In Vivo With [11C]ABP688 Positron-Emission Tomography (PET) Imaging.

DuBois JM, Rousset OG, Guiot MC, Hall JA, Reader AJ, Soucy JP, Rosa-Neto P, Kobayashi E.

Cereb Cortex. 2016 Oct 17;26(11):4170-4179. doi: 10.1093/cercor/bhw249.

10.

In vivo ketamine-induced changes in [¹¹C]ABP688 binding to metabotropic glutamate receptor subtype 5.

DeLorenzo C, DellaGioia N, Bloch M, Sanacora G, Nabulsi N, Abdallah C, Yang J, Wen R, Mann JJ, Krystal JH, Parsey RV, Carson RE, Esterlis I.

Biol Psychiatry. 2015 Feb 1;77(3):266-275. doi: 10.1016/j.biopsych.2014.06.024. Epub 2014 Jul 10.

11.

Neuroprotective effect caused by MPEP, an antagonist of metabotropic glutamate receptor mGluR5, on seizures induced by pilocarpine in 21-day-old rats.

Jesse CR, Savegnago L, Rocha JB, Nogueira CW.

Brain Res. 2008 Mar 10;1198:197-203. doi: 10.1016/j.brainres.2008.01.005. Epub 2008 Jan 15.

PMID:
18242586
12.

Binding potential of (E)-[¹¹C]ABP688 to metabotropic glutamate receptor subtype 5 is decreased by the inclusion of its ¹¹C-labelled Z-isomer.

Kawamura K, Yamasaki T, Kumata K, Furutsuka K, Takei M, Wakizaka H, Fujinaga M, Kariya K, Yui J, Hatori A, Xie L, Shimoda Y, Hashimoto H, Hayashi K, Zhang MR.

Nucl Med Biol. 2014 Jan;41(1):17-23. doi: 10.1016/j.nucmedbio.2013.09.008. Epub 2013 Oct 8.

PMID:
24183615
13.

Human PET studies of metabotropic glutamate receptor subtype 5 with 11C-ABP688.

Ametamey SM, Treyer V, Streffer J, Wyss MT, Schmidt M, Blagoev M, Hintermann S, Auberson Y, Gasparini F, Fischer UC, Buck A.

J Nucl Med. 2007 Feb;48(2):247-52.

14.

Dynamic Changes in Striatal mGluR1 But Not mGluR5 during Pathological Progression of Parkinson's Disease in Human Alpha-Synuclein A53T Transgenic Rats: A Multi-PET Imaging Study.

Yamasaki T, Fujinaga M, Kawamura K, Furutsuka K, Nengaki N, Shimoda Y, Shiomi S, Takei M, Hashimoto H, Yui J, Wakizaka H, Hatori A, Xie L, Kumata K, Zhang MR.

J Neurosci. 2016 Jan 13;36(2):375-84. doi: 10.1523/JNEUROSCI.2289-15.2016.

15.

Rat brain normalization templates for robust regional analysis of [11C]ABP688 positron emission tomography/computed tomography.

Verhaeghe J, Wyffels L, Wyckhuys T, Stroobants S, Staelens S.

Mol Imaging. 2014;13. doi: 10.2310/7290.2014.00037.

PMID:
25342447
16.

Brain mGluR5 in mice with amyloid beta pathology studied with in vivo [11C]ABP688 PET imaging and ex vivo immunoblotting.

Fang XT, Eriksson J, Antoni G, Yngve U, Cato L, Lannfelt L, Sehlin D, Syvänen S.

Neuropharmacology. 2017 Feb;113(Pt A):293-300. doi: 10.1016/j.neuropharm.2016.10.009. Epub 2016 Oct 12.

17.

Longitudinal microPET imaging of brain glucose metabolism in rat lithium-pilocarpine model of epilepsy.

Goffin K, Van Paesschen W, Dupont P, Van Laere K.

Exp Neurol. 2009 May;217(1):205-9. doi: 10.1016/j.expneurol.2009.02.008. Epub 2009 Feb 21.

PMID:
19236862
18.

Development of [(18)F]-PSS223 as a PET tracer for imaging of metabotropic glutamate receptor subtype 5 (mGluR5).

Sephton SM, Dennler P, Leutwiler DS, Mu L, Schibli R, Krämer SD, Ametamey SM.

Chimia (Aarau). 2012;66(4):201-4. doi: 10.2533/chimia.2012.201.

19.

Characterization of brain mGluR5 binding in a pilot study of late-life major depressive disorder using positron emission tomography and [¹¹C]ABP688.

DeLorenzo C, Sovago J, Gardus J, Xu J, Yang J, Behrje R, Kumar JS, Devanand DP, Pelton GH, Mathis CA, Mason NS, Gomez-Mancilla B, Aizenstein H, Mann JJ, Parsey RV.

Transl Psychiatry. 2015 Dec 8;5:e693. doi: 10.1038/tp.2015.189.

20.

Reduced metabotropic glutamate receptor 5 density in major depression determined by [(11)C]ABP688 PET and postmortem study.

Deschwanden A, Karolewicz B, Feyissa AM, Treyer V, Ametamey SM, Johayem A, Burger C, Auberson YP, Sovago J, Stockmeier CA, Buck A, Hasler G.

Am J Psychiatry. 2011 Jul;168(7):727-34. doi: 10.1176/appi.ajp.2011.09111607. Epub 2011 Apr 15.

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