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Items: 1 to 20 of 90

1.

Slug is temporally regulated by cyclin E in cell cycle and controls genome stability.

Wang WL, Huang HC, Kao SH, Hsu YC, Wang YT, Li KC, Chen YJ, Yu SL, Wang SP, Hsiao TH, Yang PC, Hong TM.

Oncogene. 2015 Feb 26;34(9):1116-25. doi: 10.1038/onc.2014.58. Epub 2014 Mar 24.

PMID:
24662826
2.

GSK3β controls epithelial-mesenchymal transition and tumor metastasis by CHIP-mediated degradation of Slug.

Kao SH, Wang WL, Chen CY, Chang YL, Wu YY, Wang YT, Wang SP, Nesvizhskii AI, Chen YJ, Hong TM, Yang PC.

Oncogene. 2014 Jun 12;33(24):3172-82. doi: 10.1038/onc.2013.279. Epub 2013 Jul 15.

3.

Phosphorylation of minichromosome maintenance protein 7 (MCM7) by cyclin/cyclin-dependent kinase affects its function in cell cycle regulation.

Wei Q, Li J, Liu T, Tong X, Ye X.

J Biol Chem. 2013 Jul 5;288(27):19715-25. doi: 10.1074/jbc.M112.449652. Epub 2013 May 17.

4.

Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression.

Wu ZQ, Li XY, Hu CY, Ford M, Kleer CG, Weiss SJ.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16654-9. doi: 10.1073/pnas.1205822109. Epub 2012 Sep 24.

5.

HMGA2 induces transcription factor Slug expression to promote epithelial-to-mesenchymal transition and contributes to colon cancer progression.

Li Y, Zhao Z, Xu C, Zhou Z, Zhu Z, You T.

Cancer Lett. 2014 Dec 1;355(1):130-40. doi: 10.1016/j.canlet.2014.09.007. Epub 2014 Sep 11.

PMID:
25218351
6.

The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion.

Fenouille N, Tichet M, Dufies M, Pottier A, Mogha A, Soo JK, Rocchi S, Mallavialle A, Galibert MD, Khammari A, Lacour JP, Ballotti R, Deckert M, Tartare-Deckert S.

PLoS One. 2012;7(7):e40378. doi: 10.1371/journal.pone.0040378. Epub 2012 Jul 20.

7.

Inducible expression of a degradation-resistant form of p27Kip1 causes growth arrest and apoptosis in breast cancer cells.

Zhang Q, Tian L, Mansouri A, Korapati AL, Johnson TJ, Claret FX.

FEBS Lett. 2005 Jul 18;579(18):3932-40.

8.

Phosphorylation of MCM3 protein by cyclin E/cyclin-dependent kinase 2 (Cdk2) regulates its function in cell cycle.

Li J, Deng M, Wei Q, Liu T, Tong X, Ye X.

J Biol Chem. 2011 Nov 18;286(46):39776-85. doi: 10.1074/jbc.M111.226464. Epub 2011 Sep 30.

9.

Regulation of E2F transcription by cyclin E-Cdk2 kinase mediated through p300/CBP co-activators.

Morris L, Allen KE, La Thangue NB.

Nat Cell Biol. 2000 Apr;2(4):232-9.

PMID:
10783242
10.

Knockdown of protein tyrosine phosphatase SHP-1 inhibits G1/S progression in prostate cancer cells through the regulation of components of the cell-cycle machinery.

Rodríguez-Ubreva FJ, Cariaga-Martinez AE, Cortés MA, Romero-De Pablos M, Ropero S, López-Ruiz P, Colás B.

Oncogene. 2010 Jan 21;29(3):345-55. doi: 10.1038/onc.2009.329. Epub 2009 Oct 19.

PMID:
19838216
12.

Functional regulation of Slug/Snail2 is dependent on GSK-3β-mediated phosphorylation.

Kim JY, Kim YM, Yang CH, Cho SK, Lee JW, Cho M.

FEBS J. 2012 Aug;279(16):2929-39. doi: 10.1111/j.1742-4658.2012.08674.x. Epub 2012 Jul 12.

13.

The loss of PIN1 deregulates cyclin E and sensitizes mouse embryo fibroblasts to genomic instability.

Yeh ES, Lew BO, Means AR.

J Biol Chem. 2006 Jan 6;281(1):241-51. Epub 2005 Oct 13.

14.

Slug regulates Cyclin D1 expression by ubiquitin-proteasome pathway in prostate cancer cells.

Ding GX, Liu J, Feng CC, Jiang HW, Xu JF, Ding Q.

Panminerva Med. 2012 Sep;54(3):219-23.

PMID:
22801439
15.

hRAD9 functions as a tumor suppressor by inducing p21-dependent senescence and suppressing epithelial-mesenchymal transition through inhibition of Slug transcription.

Wen FC, Chang TW, Tseng YL, Lee JC, Chang MC.

Carcinogenesis. 2014 Jul;35(7):1481-90. doi: 10.1093/carcin/bgu009. Epub 2014 Jan 8.

16.
17.

Fucoidan induces changes in the epithelial to mesenchymal transition and decreases metastasis by enhancing ubiquitin-dependent TGFβ receptor degradation in breast cancer.

Hsu HY, Lin TY, Hwang PA, Tseng LM, Chen RH, Tsao SM, Hsu J.

Carcinogenesis. 2013 Apr;34(4):874-84. doi: 10.1093/carcin/bgs396. Epub 2012 Dec 28.

18.

HTLV-I p30 inhibits multiple S phase entry checkpoints, decreases cyclin E-CDK2 interactions and delays cell cycle progression.

Baydoun HH, Pancewicz J, Bai X, Nicot C.

Mol Cancer. 2010 Nov 23;9:302. doi: 10.1186/1476-4598-9-302.

19.

Cell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription.

Ma T, Van Tine BA, Wei Y, Garrett MD, Nelson D, Adams PD, Wang J, Qin J, Chow LT, Harper JW.

Genes Dev. 2000 Sep 15;14(18):2298-313.

20.

Golgi-associated RhoBTB3 targets cyclin E for ubiquitylation and promotes cell cycle progression.

Lu A, Pfeffer SR.

J Cell Biol. 2013 Oct 28;203(2):233-50. doi: 10.1083/jcb.201305158. Epub 2013 Oct 21.

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