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Items: 1 to 20 of 171

1.

Regulation of Sox6 by cyclin dependent kinase 5 in brain.

Rudrabhatla P, Utreras E, Jaffe H, Kulkarni AB.

PLoS One. 2014 Mar 24;9(3):e89310. doi: 10.1371/journal.pone.0089310. eCollection 2014.

2.

Quantitative measurement of in vivo phosphorylation states of Cdk5 activator p35 by Phos-tag SDS-PAGE.

Hosokawa T, Saito T, Asada A, Fukunaga K, Hisanaga S.

Mol Cell Proteomics. 2010 Jun;9(6):1133-43. doi: 10.1074/mcp.M900578-MCP200. Epub 2010 Jan 23.

3.

Inhibition of aberrant cyclin-dependent kinase 5 activity attenuates isoflurane neurotoxicity in the developing brain.

Wang WY, Luo Y, Jia LJ, Hu SF, Lou XK, Shen SL, Lu H, Zhang HH, Yang R, Wang H, Ma ZW, Xue QS, Yu BW.

Neuropharmacology. 2014 Feb;77:90-9. doi: 10.1016/j.neuropharm.2013.09.006. Epub 2013 Sep 18.

PMID:
24055498
4.

Phosphorylation of drebrin by cyclin-dependent kinase 5 and its role in neuronal migration.

Tanabe K, Yamazaki H, Inaguma Y, Asada A, Kimura T, Takahashi J, Taoka M, Ohshima T, Furuichi T, Isobe T, Nagata K, Shirao T, Hisanaga S.

PLoS One. 2014 Mar 17;9(3):e92291. doi: 10.1371/journal.pone.0092291. eCollection 2014.

5.

The role of sex-determining region Y-box 6 in melanogenesis in alpaca melanocytes.

Du B, Liu X, Zhang P, Zhang J, Ji K, Hu S, Yang S, Liu B, Fan R.

J Dermatol Sci. 2018 Sep;91(3):268-275. doi: 10.1016/j.jdermsci.2018.05.007. Epub 2018 May 23.

PMID:
29857961
6.

Regulation of membrane association and kinase activity of Cdk5-p35 by phosphorylation of p35.

Sato K, Zhu YS, Saito T, Yotsumoto K, Asada A, Hasegawa M, Hisanaga S.

J Neurosci Res. 2007 Nov 1;85(14):3071-8.

PMID:
17671990
7.

Searching for novel Cdk5 substrates in brain by comparative phosphoproteomics of wild type and Cdk5-/- mice.

Contreras-Vallejos E, Utreras E, Bórquez DA, Prochazkova M, Terse A, Jaffe H, Toledo A, Arruti C, Pant HC, Kulkarni AB, González-Billault C.

PLoS One. 2014 Mar 21;9(3):e90363. doi: 10.1371/journal.pone.0090363. eCollection 2014.

8.

Cyclin-dependent kinase 5 regulates E2F transcription factor through phosphorylation of Rb protein in neurons.

Futatsugi A, Utreras E, Rudrabhatla P, Jaffe H, Pant HC, Kulkarni AB.

Cell Cycle. 2012 Apr 15;11(8):1603-10. doi: 10.4161/cc.20009. Epub 2012 Apr 15.

9.

Neuronal nuclear organization is controlled by cyclin-dependent kinase 5 phosphorylation of Ras Guanine nucleotide releasing factor-1.

Kesavapany S, Pareek TK, Zheng YL, Amin N, Gutkind JS, Ma W, Kulkarni AB, Grant P, Pant HC.

Neurosignals. 2006-2007;15(4):157-73. Epub 2006 Aug 18.

10.

The Cdk5/p35 kinases modulate leptin-induced STAT3 signaling.

He Y, Kastin AJ, Hsuchou H, Pan W.

J Mol Neurosci. 2009 Sep;39(1-2):49-58. doi: 10.1007/s12031-008-9174-3. Epub 2009 Jan 21.

11.

High glucose increases Cdk5 activity in podocytes via transforming growth factor-β1 signaling pathway.

Zhang Y, Li H, Hao J, Zhou Y, Liu W.

Exp Cell Res. 2014 Aug 15;326(2):219-29. doi: 10.1016/j.yexcr.2014.04.014. Epub 2014 Apr 24.

PMID:
24768698
12.

The Notch signaling inhibitor DAPT down-regulates cdk5 activity and modulates the distribution of neuronal cytoskeletal proteins.

Kanungo J, Zheng YL, Amin ND, Pant HC.

J Neurochem. 2008 Sep;106(5):2236-48. doi: 10.1111/j.1471-4159.2008.05551.x. Epub 2008 Jul 4.

13.

Valproic acid downregulates Cdk5 activity via the transcription of the p35 mRNA.

Takahashi M, Ishida M, Saito T, Ohshima T, Hisanaga S.

Biochem Biophys Res Commun. 2014 May 16;447(4):678-82. doi: 10.1016/j.bbrc.2014.04.072. Epub 2014 Apr 19.

PMID:
24755075
14.

Two Degradation Pathways of the p35 Cdk5 (Cyclin-dependent Kinase) Activation Subunit, Dependent and Independent of Ubiquitination.

Takasugi T, Minegishi S, Asada A, Saito T, Kawahara H, Hisanaga S.

J Biol Chem. 2016 Feb 26;291(9):4649-57. doi: 10.1074/jbc.M115.692871. Epub 2015 Dec 2.

15.

Enhanced activation of Ca2+/calmodulin-dependent protein kinase II upon downregulation of cyclin-dependent kinase 5-p35.

Hosokawa T, Saito T, Asada A, Ohshima T, Itakura M, Takahashi M, Fukunaga K, Hisanaga S.

J Neurosci Res. 2006 Sep;84(4):747-54.

PMID:
16802322
16.

Suppression of calpain-dependent cleavage of the CDK5 activator p35 to p25 by site-specific phosphorylation.

Kamei H, Saito T, Ozawa M, Fujita Y, Asada A, Bibb JA, Saido TC, Sorimachi H, Hisanaga S.

J Biol Chem. 2007 Jan 19;282(3):1687-94. Epub 2006 Nov 22.

17.

Phosphorylation of cyclin-dependent kinase 5 (Cdk5) at Tyr-15 is inhibited by Cdk5 activators and does not contribute to the activation of Cdk5.

Kobayashi H, Saito T, Sato K, Furusawa K, Hosokawa T, Tsutsumi K, Asada A, Kamada S, Ohshima T, Hisanaga S.

J Biol Chem. 2014 Jul 11;289(28):19627-36. doi: 10.1074/jbc.M113.501148. Epub 2014 May 28.

18.

p39, the primary activator for cyclin-dependent kinase 5 (Cdk5) in oligodendroglia, is essential for oligodendroglia differentiation and myelin repair.

Bankston AN, Li W, Zhang H, Ku L, Liu G, Papa F, Zhao L, Bibb JA, Cambi F, Tiwari-Woodruff SK, Feng Y.

J Biol Chem. 2013 Jun 21;288(25):18047-57. doi: 10.1074/jbc.M113.453688. Epub 2013 May 3.

19.

Regulation and role of cyclin-dependent kinase activity in neuronal survival and death.

Hisanaga S, Endo R.

J Neurochem. 2010 Dec;115(6):1309-21. doi: 10.1111/j.1471-4159.2010.07050.x. Epub 2010 Nov 4. Review.

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