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Items: 1 to 20 of 87

1.

A real-time method for measuring cAMP production modulated by Gαi/o-coupled metabotropic glutamate receptors.

DiRaddo JO, Miller EJ, Hathaway HA, Grajkowska E, Wroblewska B, Wolfe BB, Liotta DC, Wroblewski JT.

J Pharmacol Exp Ther. 2014 Jun;349(3):373-82. doi: 10.1124/jpet.113.211532. Epub 2014 Mar 21.

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Development of a cyclic adenosine monophosphate assay for Gi-coupled G protein-coupled receptors by utilizing the endogenous calcitonin activity in Chinese hamster ovary cells.

Wang Y, Kong Y, Shei GJ, Kang L, Cvijic ME.

Assay Drug Dev Technol. 2011 Oct;9(5):522-31. doi: 10.1089/adt.2010.0361. Epub 2011 May 11.

PMID:
21561374
5.

LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors.

Kingston AE, Ornstein PL, Wright RA, Johnson BG, Mayne NG, Burnett JP, Belagaje R, Wu S, Schoepp DD.

Neuropharmacology. 1998;37(1):1-12.

PMID:
9680254
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[3H]LY341495 binding to group II metabotropic glutamate receptors in rat brain.

Wright RA, Arnold MB, Wheeler WJ, Ornstein PL, Schoepp DD.

J Pharmacol Exp Ther. 2001 Aug;298(2):453-60.

8.

A novel assay of Gi/o-linked G protein-coupled receptor coupling to potassium channels provides new insights into the pharmacology of the group III metabotropic glutamate receptors.

Niswender CM, Johnson KA, Luo Q, Ayala JE, Kim C, Conn PJ, Weaver CD.

Mol Pharmacol. 2008 Apr;73(4):1213-24. doi: 10.1124/mol.107.041053. Epub 2008 Jan 2.

9.

Functional coupling between metabotropic glutamate receptors and G-proteins in rat cerebral cortex assessed by guanosine-5'-O-(3-[(35)S]thio)triphosphate binding assay.

Odagaki Y, Kinoshita M, Toyoshima R.

Basic Clin Pharmacol Toxicol. 2011 Sep;109(3):175-85. doi: 10.1111/j.1742-7843.2011.00705.x. Epub 2011 May 5.

11.

Characterization of [3H]-(2S,2'R,3'R)-2-(2',3'-dicarboxy-cyclopropyl)glycine ([3H]-DCG IV) binding to metabotropic mGlu2 receptor-transfected cell membranes.

Cartmell J, Adam G, Chaboz S, Henningsen R, Kemp JA, Klingelschmidt A, Metzler V, Monsma F, Schaffhauser H, Wichmann J, Mutel V.

Br J Pharmacol. 1998 Feb;123(3):497-504.

12.

Metabotropic glutamate receptor mGlu2 is resistant to homologous agonist-induced desensitization but undergoes protein kinase C-mediated heterologous desensitization.

Lennon SM, Rivero G, Matharu A, Howson PA, Jane DE, Roberts PJ, Kelly E.

Eur J Pharmacol. 2010 Dec 15;649(1-3):29-37. doi: 10.1016/j.ejphar.2010.08.038. Epub 2010 Sep 15.

PMID:
20826132
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Lidocaine enhances Galphai protein function.

Benkwitz C, Garrison JC, Linden J, Durieux ME, Hollmann MW.

Anesthesiology. 2003 Nov;99(5):1093-101.

PMID:
14576545
18.

Development of a dual glow-signal firefly and Renilla luciferase assay reagent for the analysis of G-protein coupled receptor signalling.

Stables J, Scott S, Brown S, Roelant C, Burns D, Lee MG, Rees S.

J Recept Signal Transduct Res. 1999 Jan-Jul;19(1-4):395-410.

PMID:
10071773
19.

Role of metabotropic glutamate receptor subclasses in modulation of adenylyl cyclase activity by a nootropic NS-105.

Hirouchi M, Oka M, Itoh Y, Ukai Y, Kimura K.

Eur J Pharmacol. 2000 Jan 3;387(1):9-17.

PMID:
10633154

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