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Items: 1 to 20 of 146

1.

HCMV glycoprotein B is expressed in primary glioblastomas and enhances growth and invasiveness via PDGFR-alpha activation.

Cobbs C, Khan S, Matlaf L, McAllister S, Zider A, Yount G, Rahlin K, Harkins L, Bezrookove V, Singer E, Soroceanu L.

Oncotarget. 2014 Feb 28;5(4):1091-100.

2.

Platelet-derived growth factor-alpha receptor activation is required for human cytomegalovirus infection.

Soroceanu L, Akhavan A, Cobbs CS.

Nature. 2008 Sep 18;455(7211):391-5. doi: 10.1038/nature07209. Epub 2008 Aug 13.

PMID:
18701889
3.

Human cytomegalovirus induces cellular tyrosine kinase signaling and promotes glioma cell invasiveness.

Cobbs CS, Soroceanu L, Denham S, Zhang W, Britt WJ, Pieper R, Kraus MH.

J Neurooncol. 2007 Dec;85(3):271-80. Epub 2007 Jun 23.

PMID:
17589804
4.

Human cytomegalovirus US28 found in glioblastoma promotes an invasive and angiogenic phenotype.

Soroceanu L, Matlaf L, Bezrookove V, Harkins L, Martinez R, Greene M, Soteropoulos P, Cobbs CS.

Cancer Res. 2011 Nov 1;71(21):6643-53. doi: 10.1158/0008-5472.CAN-11-0744. Epub 2011 Sep 7.

5.

Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans.

Feng H, Hu B, Liu KW, Li Y, Lu X, Cheng T, Yiin JJ, Lu S, Keezer S, Fenton T, Furnari FB, Hamilton RL, Vuori K, Sarkaria JN, Nagane M, Nishikawa R, Cavenee WK, Cheng SY.

J Clin Invest. 2011 Dec;121(12):4670-84. doi: 10.1172/JCI58559. Epub 2011 Nov 14.

6.

Protein kinase A-dependent phosphorylation of Dock180 at serine residue 1250 is important for glioma growth and invasion stimulated by platelet derived-growth factor receptor α.

Feng H, Li Y, Yin Y, Zhang W, Hou Y, Zhang L, Li Z, Xie B, Gao WQ, Sarkaria JN, Raizer JJ, James CD, Parsa AT, Hu B, Cheng SY.

Neuro Oncol. 2015 Jun;17(6):832-42. doi: 10.1093/neuonc/nou323. Epub 2014 Dec 2.

7.

Cytomegalovirus Immediate-Early Proteins Promote Stemness Properties in Glioblastoma.

Soroceanu L, Matlaf L, Khan S, Akhavan A, Singer E, Bezrookove V, Decker S, Ghanny S, Hadaczek P, Bengtsson H, Ohlfest J, Luciani-Torres MG, Harkins L, Perry A, Guo H, Soteropoulos P, Cobbs CS.

Cancer Res. 2015 Aug 1;75(15):3065-76. doi: 10.1158/0008-5472.CAN-14-3307.

8.

Modulation of oncogenic phenotype in human glioma cells by cytomegalovirus IE1-mediated mitogenicity.

Cobbs CS, Soroceanu L, Denham S, Zhang W, Kraus MH.

Cancer Res. 2008 Feb 1;68(3):724-30. doi: 10.1158/0008-5472.CAN-07-2291.

9.

Consensus on the role of human cytomegalovirus in glioblastoma.

Dziurzynski K, Chang SM, Heimberger AB, Kalejta RF, McGregor Dallas SR, Smit M, Soroceanu L, Cobbs CS; HCMV and Gliomas Symposium.

Neuro Oncol. 2012 Mar;14(3):246-55. doi: 10.1093/neuonc/nor227. Epub 2012 Feb 8.

10.

Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion.

Feng H, Liu KW, Guo P, Zhang P, Cheng T, McNiven MA, Johnson GR, Hu B, Cheng SY.

Oncogene. 2012 May 24;31(21):2691-702. doi: 10.1038/onc.2011.436. Epub 2011 Sep 26.

11.

PDGF receptor-α does not promote HCMV entry into epithelial and endothelial cells but increased quantities stimulate entry by an abnormal pathway.

Vanarsdall AL, Wisner TW, Lei H, Kazlauskas A, Johnson DC.

PLoS Pathog. 2012 Sep;8(9):e1002905. doi: 10.1371/journal.ppat.1002905. Epub 2012 Sep 13.

12.

Cytomegalovirus contributes to glioblastoma in the context of tumor suppressor mutations.

Price RL, Song J, Bingmer K, Kim TH, Yi JY, Nowicki MO, Mo X, Hollon T, Murnan E, Alvarez-Breckenridge C, Fernandez S, Kaur B, Rivera A, Oglesbee M, Cook C, Chiocca EA, Kwon CH.

Cancer Res. 2013 Jun 1;73(11):3441-50. doi: 10.1158/0008-5472.CAN-12-3846.

13.

Human cytomegalovirus glycoprotein complex gH/gL/gO uses PDGFR-α as a key for entry.

Wu Y, Prager A, Boos S, Resch M, Brizic I, Mach M, Wildner S, Scrivano L, Adler B.

PLoS Pathog. 2017 Apr 12;13(4):e1006281. doi: 10.1371/journal.ppat.1006281. eCollection 2017 Apr.

14.

Human cytomegalovirus gene expression in long-term infected glioma stem cells.

Fiallos E, Judkins J, Matlaf L, Prichard M, Dittmer D, Cobbs C, Soroceanu L.

PLoS One. 2014 Dec 30;9(12):e116178. doi: 10.1371/journal.pone.0116178. eCollection 2014.

15.

Significant association of multiple human cytomegalovirus genomic Loci with glioblastoma multiforme samples.

Ranganathan P, Clark PA, Kuo JS, Salamat MS, Kalejta RF.

J Virol. 2012 Jan;86(2):854-64. doi: 10.1128/JVI.06097-11. Epub 2011 Nov 16.

16.

SHP-2/PTPN11 mediates gliomagenesis driven by PDGFRA and INK4A/ARF aberrations in mice and humans.

Liu KW, Feng H, Bachoo R, Kazlauskas A, Smith EM, Symes K, Hamilton RL, Nagane M, Nishikawa R, Hu B, Cheng SY.

J Clin Invest. 2011 Mar;121(3):905-17. doi: 10.1172/JCI43690.

17.

Cytomegalovirus and brain tumor: epidemiology, biology and therapeutic aspects.

Cobbs CS.

Curr Opin Oncol. 2013 Nov;25(6):682-8. doi: 10.1097/CCO.0000000000000005. Review.

PMID:
24097102
18.

Cytomegalovirus pp71 protein is expressed in human glioblastoma and promotes pro-angiogenic signaling by activation of stem cell factor.

Matlaf LA, Harkins LE, Bezrookove V, Cobbs CS, Soroceanu L.

PLoS One. 2013 Jul 5;8(7):e68176. doi: 10.1371/journal.pone.0068176. Print 2013.

19.

Cytomegalovirus infection induces a stem cell phenotype in human primary glioblastoma cells: prognostic significance and biological impact.

Fornara O, Bartek J Jr, Rahbar A, Odeberg J, Khan Z, Peredo I, Hamerlik P, Bartek J, Stragliotto G, Landázuri N, Söderberg-Nauclér C.

Cell Death Differ. 2016 Feb;23(2):261-9. doi: 10.1038/cdd.2015.91. Epub 2015 Jul 3.

20.

PDGFA/PDGFRα-regulated GOLM1 promotes human glioma progression through activation of AKT.

Xu R, Ji J, Zhang X, Han M, Zhang C, Xu Y, Wei Y, Wang S, Huang B, Chen A, Zhang D, Zhang Q, Li W, Jiang Z, Wang J, Li X.

J Exp Clin Cancer Res. 2017 Dec 28;36(1):193. doi: 10.1186/s13046-017-0665-3.

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