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Items: 1 to 20 of 131

1.

The influence of cell growth and enzyme activity changes on intracellular metabolite dynamics in AGE1.HN.AAT cells.

Rath AG, Rehberg M, Janke R, Genzel Y, Scholz S, Noll T, Rose T, Sandig V, Reichl U.

J Biotechnol. 2014 May 20;178:43-53. doi: 10.1016/j.jbiotec.2014.03.012.

PMID:
24657347
2.

Primary metabolism in the new human cell line AGE1.HN at various substrate levels: increased metabolic efficiency and α1-antitrypsin production at reduced pyruvate load.

Niklas J, Priesnitz C, Rose T, Sandig V, Heinzle E.

Appl Microbiol Biotechnol. 2012 Feb;93(4):1637-50. doi: 10.1007/s00253-011-3526-6.

PMID:
21842438
3.

Metabolic adaptation of MDCK cells to different growth conditions: effects on catalytic activities of central metabolic enzymes.

Janke R, Genzel Y, Händel N, Wahl A, Reichl U.

Biotechnol Bioeng. 2011 Nov;108(11):2691-704. doi: 10.1002/bit.23215.

PMID:
21618469
4.

Quantitative characterization of metabolism and metabolic shifts during growth of the new human cell line AGE1.HN using time resolved metabolic flux analysis.

Niklas J, Schräder E, Sandig V, Noll T, Heinzle E.

Bioprocess Biosyst Eng. 2011 Jun;34(5):533-45. doi: 10.1007/s00449-010-0502-y.

5.
6.

Changes in intracellular metabolite pools during growth of adherent MDCK cells in two different media.

Rehberg M, Rath A, Ritter JB, Genzel Y, Reichl U.

Appl Microbiol Biotechnol. 2014 Jan;98(1):385-97. doi: 10.1007/s00253-013-5329-4.

PMID:
24169951
8.

Comparison of metabolic flux distributions for MDCK cell growth in glutamine- and pyruvate-containing media.

Sidorenko Y, Wahl A, Dauner M, Genzel Y, Reichl U.

Biotechnol Prog. 2008 Mar-Apr;24(2):311-20. doi: 10.1021/bp0702673.

PMID:
18215054
9.
10.

Metabolite channeling and compartmentation in the human cell line AGE1.HN determined by 13C labeling experiments and 13C metabolic flux analysis.

Niklas J, Sandig V, Heinzle E.

J Biosci Bioeng. 2011 Dec;112(6):616-23. doi: 10.1016/j.jbiosc.2011.07.021.

PMID:
21865082
11.

Glucose and glutamine metabolism of a murine B-lymphocyte hybridoma grown in batch culture.

Fitzpatrick L, Jenkins HA, Butler M.

Appl Biochem Biotechnol. 1993 Nov;43(2):93-116.

PMID:
8267405
12.

Quercetin treatment changes fluxes in the primary metabolism and increases culture longevity and recombinant α₁-antitrypsin production in human AGE1.HN cells.

Niklas J, Nonnenmacher Y, Rose T, Sandig V, Heinzle E.

Appl Microbiol Biotechnol. 2012 Apr;94(1):57-67. doi: 10.1007/s00253-011-3811-4.

PMID:
22202969
13.

Metabolic analysis of antibody producing CHO cells in fed-batch production.

Dean J, Reddy P.

Biotechnol Bioeng. 2013 Jun;110(6):1735-47. doi: 10.1002/bit.24826.

PMID:
23296898
14.

Metabolic flux analysis of CHO cells at growth and non-growth phases using isotopic tracers and mass spectrometry.

Ahn WS, Antoniewicz MR.

Metab Eng. 2011 Sep;13(5):598-609. doi: 10.1016/j.ymben.2011.07.002.

PMID:
21821143
15.
16.

Metabolic flux rearrangement in the amino acid metabolism reduces ammonia stress in the α1-antitrypsin producing human AGE1.HN cell line.

Priesnitz C, Niklas J, Rose T, Sandig V, Heinzle E.

Metab Eng. 2012 Mar;14(2):128-37. doi: 10.1016/j.ymben.2012.01.001.

PMID:
22289170
17.

A single nutrient feed supports both chemically defined NS0 and CHO fed-batch processes: Improved productivity and lactate metabolism.

Ma N, Ellet J, Okediadi C, Hermes P, McCormick E, Casnocha S.

Biotechnol Prog. 2009 Sep-Oct;25(5):1353-63. doi: 10.1002/btpr.238.

PMID:
19637321
18.

Fluxes and enzyme activities in central metabolism of myeloma cells grown in chemostat culture.

Vriezen N, van Dijken JP.

Biotechnol Bioeng. 1998 Jul 5;59(1):28-39.

PMID:
10099311
19.

Glycolytic, glutaminolytic and pentose-phosphate pathways in promyelocytic HL60 and DMSO-differentiated HL60 cells.

Ahmed N, Williams JF, Weidemann MJ.

Biochem Mol Biol Int. 1993 Apr;29(6):1055-67.

PMID:
8330014
20.

Elucidating the effects of postinduction glutamine feeding on the growth and productivity of CHO cells.

Sheikholeslami Z, Jolicoeur M, Henry O.

Biotechnol Prog. 2014 May-Jun;30(3):535-46. doi: 10.1002/btpr.1907.

PMID:
24692260
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