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Overexpression of HOXB9 promotes metastasis and indicates poor prognosis in colon cancer.

Huang K, Yuan R, Wang K, Hu J, Huang Z, Yan C, Shen W, Shao J.

Chin J Cancer Res. 2014 Feb;26(1):72-80. doi: 10.3978/j.issn.1000-9604.2014.01.11.


Homeobox B9 is overexpressed in hepatocellular carcinomas and promotes tumor cell proliferation both in vitro and in vivo.

Li F, Dong L, Xing R, Wang L, Luan F, Yao C, Ji X, Bai L.

Biochem Biophys Res Commun. 2014 Feb 7;444(2):241-7. doi: 10.1016/j.bbrc.2014.01.059. Epub 2014 Jan 22.


Elevated HOXB9 expression promotes differentiation and predicts a favourable outcome in colon adenocarcinoma patients.

Zhan J, Niu M, Wang P, Zhu X, Li S, Song J, He H, Wang Y, Xue L, Fang W, Zhang H.

Br J Cancer. 2014 Aug 26;111(5):883-93. doi: 10.1038/bjc.2014.387. Epub 2014 Jul 15.


HOXB9 expression promoting tumor cell proliferation and angiogenesis is associated with clinical outcomes in breast cancer patients.

Seki H, Hayashida T, Jinno H, Hirose S, Sakata M, Takahashi M, Maheswaran S, Mukai M, Kitagawa Y.

Ann Surg Oncol. 2012 Jun;19(6):1831-40. doi: 10.1245/s10434-012-2295-5. Epub 2012 Mar 7.


Bevacizumab terminates homeobox B9-induced tumor proliferation by silencing microenvironmental communication.

Hoshino Y, Hayashida T, Hirata A, Takahashi H, Chiba N, Ohmura M, Wakui M, Jinno H, Hasegawa H, Maheswaran S, Suematsu M, Kitagawa Y.

Mol Cancer. 2014 May 5;13:102. doi: 10.1186/1476-4598-13-102.


Ubiquitin-like protein FAT10 promotes the invasion and metastasis of hepatocellular carcinoma by modifying β-catenin degradation.

Yuan R, Wang K, Hu J, Yan C, Li M, Yu X, Liu X, Lei J, Guo W, Wu L, Hong K, Shao J.

Cancer Res. 2014 Sep 15;74(18):5287-300. doi: 10.1158/0008-5472.CAN-14-0284. Epub 2014 Jul 23.


Overexpressed homeobox B9 regulates oncogenic activities by transforming growth factor-β1 in gliomas.

Fang L, Xu Y, Zou L.

Biochem Biophys Res Commun. 2014 Mar 28;446(1):272-9. doi: 10.1016/j.bbrc.2014.02.095. Epub 2014 Feb 28.


An E2F1-HOXB9 transcriptional circuit is associated with breast cancer progression.

Zhussupova A, Hayashida T, Takahashi M, Miyao K, Okazaki H, Jinno H, Kitagawa Y.

PLoS One. 2014 Aug 19;9(8):e105285. doi: 10.1371/journal.pone.0105285. eCollection 2014.


HOXB9 promotes epithelial-to-mesenchymal transition via transforming growth factor-β1 pathway in hepatocellular carcinoma cells.

Sha L, Dong L, Lv L, Bai L, Ji X.

Clin Exp Med. 2015 Feb;15(1):55-64. doi: 10.1007/s10238-014-0276-7. Epub 2014 Aug 1.


Overexpression of HMGA2 promotes tongue cancer metastasis through EMT pathway.

Zhao XP, Zhang H, Jiao JY, Tang DX, Wu YL, Pan CB.

J Transl Med. 2016 Jan 27;14:26. doi: 10.1186/s12967-016-0777-0.


Decreased expression of HOXB9 is related to poor overall survival in patients with gastric carcinoma.

Sha S, Gu Y, Xu B, Hu H, Yang Y, Kong X, Wu K.

Dig Liver Dis. 2013 May;45(5):422-9. doi: 10.1016/j.dld.2012.12.004. Epub 2013 Jan 14.


GalNAc-T14 promotes metastasis through Wnt dependent HOXB9 expression in lung adenocarcinoma.

Kwon OS, Oh E, Park JR, Lee JS, Bae GY, Koo JH, Kim H, Choi YL, Choi YS, Kim J, Cha HJ.

Oncotarget. 2015 Dec 8;6(39):41916-28. doi: 10.18632/oncotarget.6019.


Positive MACC1 expression correlates with invasive behaviors and postoperative liver metastasis in colon cancer.

Ge Y, Meng X, Zhou Y, Zhang J, Ding Y.

Int J Clin Exp Med. 2015 Jan 15;8(1):1094-100. eCollection 2015.


Overexpression of forkhead Box C2 promotes tumor metastasis and indicates poor prognosis in colon cancer via regulating epithelial-mesenchymal transition.

Li Q, Wu J, Wei P, Xu Y, Zhuo C, Wang Y, Li D, Cai S.

Am J Cancer Res. 2015 May 15;5(6):2022-34. eCollection 2015.


Homeobox B9 mediates resistance to anti-VEGF therapy in colorectal cancer patients.

Carbone C, Piro G, Simionato F, Ligorio F, Cremolini C, Loupakis F, Alì G, Rossini D, Merz V, Santoro R, Zecchetto C, Zanotto M, Di Nicolantonio F, Bardelli A, Fontanini G, Tortora G, Melisi D.

Clin Cancer Res. 2017 Mar 15. pii: clincanres.3153.2016. doi: 10.1158/1078-0432.CCR-16-3153. [Epub ahead of print]


Downregulation of BRAF activated non-coding RNA is associated with poor prognosis for non-small cell lung cancer and promotes metastasis by affecting epithelial-mesenchymal transition.

Sun M, Liu XH, Wang KM, Nie FQ, Kong R, Yang JS, Xia R, Xu TP, Jin FY, Liu ZJ, Chen JF, Zhang EB, De W, Wang ZX.

Mol Cancer. 2014 Mar 21;13:68. doi: 10.1186/1476-4598-13-68.


Zinc finger E-box binding homeobox 1 promotes invasion and bone metastasis of small cell lung cancer in vitro and in vivo.

Liu Y, Zhang N, Wang Y, Xu M, Liu N, Pang X, Cao J, Ma N, Pang H, Liu L, Zhang H.

Cancer Sci. 2012 Aug;103(8):1420-8. doi: 10.1111/j.1349-7006.2012.02347.x. Epub 2012 Jul 11.


HoxB9 promotes the migration and invasion via TGF-β1/Smad2/Slug signaling pathway in oral squamous cell carcinoma.

Xue M, Zhu FY, Chen L, Wang K.

Am J Transl Res. 2017 Mar 15;9(3):1151-1161. eCollection 2017.


Semaphorin 4D expression is associated with a poor clinical outcome in cervical cancer patients.

Liu H, Yang Y, Xiao J, Yang S, Liu Y, Kang W, Li X, Zhang F.

Microvasc Res. 2014 May;93:1-8. doi: 10.1016/j.mvr.2014.02.007. Epub 2014 Mar 3.


Kindlin-2 induced by TGF-β signaling promotes pancreatic ductal adenocarcinoma progression through downregulation of transcriptional factor HOXB9.

Zhan J, Song J, Wang P, Chi X, Wang Y, Guo Y, Fang W, Zhang H.

Cancer Lett. 2015 May 28;361(1):75-85. doi: 10.1016/j.canlet.2015.02.039. Epub 2015 Feb 24.


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