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Items: 1 to 20 of 502

1.

A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis.

Coward WR, Feghali-Bostwick CA, Jenkins G, Knox AJ, Pang L.

FASEB J. 2014 Jul;28(7):3183-96. doi: 10.1096/fj.13-241760. Epub 2014 Mar 20.

2.

Interplay between EZH2 and G9a Regulates CXCL10 Gene Repression in Idiopathic Pulmonary Fibrosis.

Coward WR, Brand OJ, Pasini A, Jenkins G, Knox AJ, Pang L.

Am J Respir Cell Mol Biol. 2018 Apr;58(4):449-460. doi: 10.1165/rcmb.2017-0286OC.

PMID:
29053336
3.

Defective histone acetylation is responsible for the diminished expression of cyclooxygenase 2 in idiopathic pulmonary fibrosis.

Coward WR, Watts K, Feghali-Bostwick CA, Knox A, Pang L.

Mol Cell Biol. 2009 Aug;29(15):4325-39. doi: 10.1128/MCB.01776-08. Epub 2009 Jun 1.

4.

The histone H3 lysine 9 methyltransferases G9a and GLP regulate polycomb repressive complex 2-mediated gene silencing.

Mozzetta C, Pontis J, Fritsch L, Robin P, Portoso M, Proux C, Margueron R, Ait-Si-Ali S.

Mol Cell. 2014 Jan 23;53(2):277-89. doi: 10.1016/j.molcel.2013.12.005. Epub 2014 Jan 2.

5.

Repression of IP-10 by interactions between histone deacetylation and hypermethylation in idiopathic pulmonary fibrosis.

Coward WR, Watts K, Feghali-Bostwick CA, Jenkins G, Pang L.

Mol Cell Biol. 2010 Jun;30(12):2874-86. doi: 10.1128/MCB.01527-09. Epub 2010 Apr 19.

6.

Epigenetic regulation of cell adhesion and communication by enhancer of zeste homolog 2 in human endothelial cells.

Dreger H, Ludwig A, Weller A, Stangl V, Baumann G, Meiners S, Stangl K.

Hypertension. 2012 Nov;60(5):1176-83. doi: 10.1161/HYPERTENSIONAHA.112.191098. Epub 2012 Sep 10.

7.

Down-regulation of the histone methyltransferase EZH2 contributes to the epigenetic programming of decidualizing human endometrial stromal cells.

Grimaldi G, Christian M, Steel JH, Henriet P, Poutanen M, Brosens JJ.

Mol Endocrinol. 2011 Nov;25(11):1892-903. doi: 10.1210/me.2011-1139. Epub 2011 Sep 8.

8.

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation.

Kondo Y, Shen L, Cheng AS, Ahmed S, Boumber Y, Charo C, Yamochi T, Urano T, Furukawa K, Kwabi-Addo B, Gold DL, Sekido Y, Huang TH, Issa JP.

Nat Genet. 2008 Jun;40(6):741-50. doi: 10.1038/ng.159. Epub 2008 May 18.

PMID:
18488029
9.

Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2.

Friedman J, Cho WK, Chu CK, Keedy KS, Archin NM, Margolis DM, Karn J.

J Virol. 2011 Sep;85(17):9078-89. doi: 10.1128/JVI.00836-11. Epub 2011 Jun 29.

10.

EZH2 dependent H3K27me3 is involved in epigenetic silencing of ID4 in prostate cancer.

Chinaranagari S, Sharma P, Chaudhary J.

Oncotarget. 2014 Aug 30;5(16):7172-82.

11.

Multiple Histone Lysine Methyltransferases Are Required for the Establishment and Maintenance of HIV-1 Latency.

Nguyen K, Das B, Dobrowolski C, Karn J.

MBio. 2017 Feb 28;8(1). pii: e00133-17. doi: 10.1128/mBio.00133-17.

12.

Targeting of EZH2 to a defined genomic site is sufficient for recruitment of Dnmt3a but not de novo DNA methylation.

Rush M, Appanah R, Lee S, Lam LL, Goyal P, Lorincz MC.

Epigenetics. 2009 Aug 16;4(6):404-14. Epub 2009 Aug 29.

PMID:
19717977
13.

Yin Yang 1-mediated epigenetic silencing of tumour-suppressive microRNAs activates nuclear factor-κB in hepatocellular carcinoma.

Tsang DP, Wu WK, Kang W, Lee YY, Wu F, Yu Z, Xiong L, Chan AW, Tong JH, Yang W, Li MS, Lau SS, Li X, Lee SD, Yang Y, Lai PB, Yu DY, Xu G, Lo KW, Chan MT, Wang H, Lee TL, Yu J, Wong N, Yip KY, To KF, Cheng AS.

J Pathol. 2016 Apr;238(5):651-64. doi: 10.1002/path.4688.

PMID:
26800240
14.
15.

Regulation of the expression of claudin 23 by the enhancer of zeste 2 polycomb group protein in colorectal cancer.

Maryan N, Statkiewicz M, Mikula M, Goryca K, Paziewska A, Strzałkowska A, Dabrowska M, Bujko M, Ostrowski J.

Mol Med Rep. 2015 Jul;12(1):728-36. doi: 10.3892/mmr.2015.3378. Epub 2015 Feb 19.

PMID:
25695204
16.

UHRF1 is associated with epigenetic silencing of BRCA1 in sporadic breast cancer.

Jin W, Chen L, Chen Y, Xu SG, Di GH, Yin WJ, Wu J, Shao ZM.

Breast Cancer Res Treat. 2010 Sep;123(2):359-73. doi: 10.1007/s10549-009-0652-2. Epub 2009 Nov 27.

PMID:
19943104
17.

The SRA protein UHRF1 promotes epigenetic crosstalks and is involved in prostate cancer progression.

Babbio F, Pistore C, Curti L, Castiglioni I, Kunderfranco P, Brino L, Oudet P, Seiler R, Thalman GN, Roggero E, Sarti M, Pinton S, Mello-Grand M, Chiorino G, Catapano CV, Carbone GM, Bonapace IM.

Oncogene. 2012 Nov 15;31(46):4878-87. doi: 10.1038/onc.2011.641. Epub 2012 Feb 13.

PMID:
22330138
18.

Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation.

Popovic R, Martinez-Garcia E, Giannopoulou EG, Zhang Q, Zhang Q, Ezponda T, Shah MY, Zheng Y, Will CM, Small EC, Hua Y, Bulic M, Jiang Y, Carrara M, Calogero RA, Kath WL, Kelleher NL, Wang JP, Elemento O, Licht JD.

PLoS Genet. 2014 Sep 4;10(9):e1004566. doi: 10.1371/journal.pgen.1004566. eCollection 2014 Sep.

19.

PRC2-independent chromatin compaction and transcriptional repression in cancer.

Vallot C, Hérault A, Boyle S, Bickmore WA, Radvanyi F.

Oncogene. 2015 Feb 5;34(6):741-51. doi: 10.1038/onc.2013.604. Epub 2014 Jan 27.

PMID:
24469045
20.

Epigenetic regulation of cyclooxygenase-2 by methylation of c8orf4 in pulmonary fibrosis.

Evans IC, Barnes JL, Garner IM, Pearce DR, Maher TM, Shiwen X, Renzoni EA, Wells AU, Denton CP, Laurent GJ, Abraham DJ, McAnulty RJ.

Clin Sci (Lond). 2016 Apr;130(8):575-86. doi: 10.1042/CS20150697. Epub 2016 Jan 7.

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