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Items: 1 to 20 of 630

1.

Longikaurin A, a natural ent-kaurane, induces G2/M phase arrest via downregulation of Skp2 and apoptosis induction through ROS/JNK/c-Jun pathway in hepatocellular carcinoma cells.

Liao YJ, Bai HY, Li ZH, Zou J, Chen JW, Zheng F, Zhang JX, Mai SJ, Zeng MS, Sun HD, Pu JX, Xie D.

Cell Death Dis. 2014 Mar 20;5:e1137. doi: 10.1038/cddis.2014.66.

2.

Wentilactone B induces G2/M phase arrest and apoptosis via the Ras/Raf/MAPK signaling pathway in human hepatoma SMMC-7721 cells.

Zhang Z, Miao L, Lv C, Sun H, Wei S, Wang B, Huang C, Jiao B.

Cell Death Dis. 2013 Jun 6;4:e657. doi: 10.1038/cddis.2013.182.

3.

Oridonin induces G2/M cell cycle arrest and apoptosis through MAPK and p53 signaling pathways in HepG2 cells.

Wang H, Ye Y, Chui JH, Zhu GY, Li YW, Fong DW, Yu ZL.

Oncol Rep. 2010 Sep;24(3):647-51.

PMID:
20664969
4.

Romidepsin induces G2/M phase arrest via Erk/cdc25C/cdc2/cyclinB pathway and apoptosis induction through JNK/c-Jun/caspase3 pathway in hepatocellular carcinoma cells.

Sun WJ, Huang H, He B, Hu DH, Li PH, Yu YJ, Zhou XH, Lv Z, Zhou L, Hu TY, Yao ZC, Lu MD, Shen X, Zheng ZQ.

Biochem Pharmacol. 2017 Mar 1;127:90-100. doi: 10.1016/j.bcp.2016.12.008. Epub 2016 Dec 22.

PMID:
28012958
5.

Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1.

Lin HP, Lin CY, Huo C, Hsiao PH, Su LC, Jiang SS, Chan TM, Chang CH, Chen LT, Kung HJ, Wang HD, Chuu CP.

Oncotarget. 2015 Mar 30;6(9):6684-707.

6.

Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells.

Wang CC, Chiang YM, Sung SC, Hsu YL, Chang JK, Kuo PL.

Cancer Lett. 2008 Jan 18;259(1):82-98. Epub 2007 Nov 19.

PMID:
18023967
8.

Millepachine, a novel chalcone, induces G2/M arrest by inhibiting CDK1 activity and causing apoptosis via ROS-mitochondrial apoptotic pathway in human hepatocarcinoma cells in vitro and in vivo.

Wu W, Ye H, Wan L, Han X, Wang G, Hu J, Tang M, Duan X, Fan Y, He S, Huang L, Pei H, Wang X, Li X, Xie C, Zhang R, Yuan Z, Mao Y, Wei Y, Chen L.

Carcinogenesis. 2013 Jul;34(7):1636-43. doi: 10.1093/carcin/bgt087. Epub 2013 Mar 7.

PMID:
23471882
9.

Juglanin induces apoptosis and autophagy in human breast cancer progression via ROS/JNK promotion.

Sun ZL, Dong JL, Wu J.

Biomed Pharmacother. 2017 Jan;85:303-312. doi: 10.1016/j.biopha.2016.11.030. Epub 2016 Nov 26.

PMID:
27899257
10.

Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up-regulating H-Ras and N-Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells.

Liu W, Ning R, Chen RN, Huang XF, Dai QS, Hu JH, Wang YW, Wu LL, Xiong J, Hu G, Guo QL, Yang J, Wang H.

Mol Carcinog. 2016 May;55(5):440-57. doi: 10.1002/mc.22293. Epub 2015 Feb 14.

PMID:
25683703
11.

Antitumor activity of di-n-butyl-(2,6-difluorobenzohydroxamato)tin(IV) against human gastric carcinoma SGC-7901 cells via G2/M cell cycle arrest and cell apoptosis.

Yunlan L, Juan Z, Qingshan L.

PLoS One. 2014 Mar 18;9(3):e90793. doi: 10.1371/journal.pone.0090793. eCollection 2014.

12.

Hydrogen peroxide inducible clone-5 mediates reactive oxygen species signaling for hepatocellular carcinoma progression.

Wu JR, Hu CT, You RI, Pan SM, Cheng CC, Lee MC, Wu CC, Chang YJ, Lin SC, Chen CS, Lin TY, Wu WS.

Oncotarget. 2015 Oct 20;6(32):32526-44. doi: 10.18632/oncotarget.5322.

13.

Telekin suppresses human hepatocellular carcinoma cells in vitro by inducing G2/M phase arrest via the p38 MAPK signaling pathway.

Li L, Zheng BB, Ma LS, Sun X, Chang JJ, Xie WD, Li X.

Acta Pharmacol Sin. 2014 Oct;35(10):1311-22. doi: 10.1038/aps.2014.74. Epub 2014 Sep 1.

14.

Inhibitory effect of oleanolic acid on hepatocellular carcinoma via ERK-p53-mediated cell cycle arrest and mitochondrial-dependent apoptosis.

Wang X, Bai H, Zhang X, Liu J, Cao P, Liao N, Zhang W, Wang Z, Hai C.

Carcinogenesis. 2013 Jun;34(6):1323-30. doi: 10.1093/carcin/bgt058. Epub 2013 Feb 12.

PMID:
23404993
15.

Xylocydine, a novel Cdk inhibitor, is an effective inducer of apoptosis in hepatocellular carcinoma cells in vitro and in vivo.

Cho SJ, Lee SS, Kim YJ, Park BD, Choi JS, Liu L, Ham YM, Moon Kim B, Lee SK.

Cancer Lett. 2010 Jan 28;287(2):196-206. doi: 10.1016/j.canlet.2009.06.011. Epub 2009 Jul 17.

PMID:
19616371
16.

Derivate isocorydine inhibits cell proliferation in hepatocellular carcinoma cell lines by inducing G2/M cell cycle arrest and apoptosis.

Chen L, Tian H, Li M, Ge C, Zhao F, Zhang L, Li H, Liu J, Wang T, Yao M, Li J.

Tumour Biol. 2016 May;37(5):5951-61. doi: 10.1007/s13277-015-4362-6. Epub 2015 Nov 23.

PMID:
26596832
17.

Deoxyelephantopin impairs growth of cervical carcinoma SiHa cells and induces apoptosis by targeting multiple molecular signaling pathways.

Farha AK, Dhanya SR, Mangalam SN, Geetha BS, Latha PG, Remani P.

Cell Biol Toxicol. 2014 Dec;30(6):331-43. doi: 10.1007/s10565-014-9288-z. Epub 2014 Sep 27.

PMID:
25260383
18.

TQ inhibits hepatocellular carcinoma growth in vitro and in vivo via repression of Notch signaling.

Ke X, Zhao Y, Lu X, Wang Z, Liu Y, Ren M, Lu G, Zhang D, Sun Z, Xu Z, Song JH, Cheng Y, Meltzer SJ, He S.

Oncotarget. 2015 Oct 20;6(32):32610-21. doi: 10.18632/oncotarget.5362.

19.

Icariin, a natural flavonol glycoside, induces apoptosis in human hepatoma SMMC-7721 cells via a ROS/JNK-dependent mitochondrial pathway.

Li S, Dong P, Wang J, Zhang J, Gu J, Wu X, Wu W, Fei X, Zhang Z, Wang Y, Quan Z, Liu Y.

Cancer Lett. 2010 Dec 8;298(2):222-30. doi: 10.1016/j.canlet.2010.07.009. Epub 2010 Jul 31.

PMID:
20674153
20.

6-Dehydrogingerdione, an active constituent of dietary ginger, induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human breast cancer cells.

Hsu YL, Chen CY, Hou MF, Tsai EM, Jong YJ, Hung CH, Kuo PL.

Mol Nutr Food Res. 2010 Sep;54(9):1307-17. doi: 10.1002/mnfr.200900125.

PMID:
20175081

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