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The role of heat shock protein 90 in migration and proliferation of vascular smooth muscle cells in the development of atherosclerosis.

Kim J, Jang SW, Park E, Oh M, Park S, Ko J.

J Mol Cell Cardiol. 2014 Jul;72:157-67. doi: 10.1016/j.yjmcc.2014.03.008. Epub 2014 Mar 18.


Heat shock protein 90 inhibitors attenuate inflammatory responses in atherosclerosis.

Madrigal-Matute J, López-Franco O, Blanco-Colio LM, Muñoz-García B, Ramos-Mozo P, Ortega L, Egido J, Martín-Ventura JL.

Cardiovasc Res. 2010 May 1;86(2):330-7. doi: 10.1093/cvr/cvq046. Epub 2010 Feb 12.


Cortistatin inhibits migration and proliferation of human vascular smooth muscle cells and decreases neointimal formation on carotid artery ligation.

Duran-Prado M, Morell M, Delgado-Maroto V, Castaño JP, Aneiros-Fernandez J, de Lecea L, Culler MD, Hernandez-Cortes P, O'Valle F, Delgado M.

Circ Res. 2013 May 24;112(11):1444-55. doi: 10.1161/CIRCRESAHA.112.300695. Epub 2013 Apr 17.


Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo.

Lang SA, Klein D, Moser C, Gaumann A, Glockzin G, Dahlke MH, Dietmaier W, Bolder U, Schlitt HJ, Geissler EK, Stoeltzing O.

Mol Cancer Ther. 2007 Mar;6(3):1123-32.


Increased atherosclerosis and vascular smooth muscle cell activation in AIF-1 transgenic mice fed a high-fat diet.

Sommerville LJ, Kelemen SE, Ellison SP, England RN, Autieri MV.

Atherosclerosis. 2012 Jan;220(1):45-52. doi: 10.1016/j.atherosclerosis.2011.07.095. Epub 2011 Aug 6.


Absence of Akt1 reduces vascular smooth muscle cell migration and survival and induces features of plaque vulnerability and cardiac dysfunction during atherosclerosis.

Fernández-Hernando C, József L, Jenkins D, Di Lorenzo A, Sessa WC.

Arterioscler Thromb Vasc Biol. 2009 Dec;29(12):2033-40. doi: 10.1161/ATVBAHA.109.196394. Epub 2009 Sep 17.


HSP90 inhibition by 17-DMAG attenuates oxidative stress in experimental atherosclerosis.

Madrigal-Matute J, Fernandez-Garcia CE, Gomez-Guerrero C, Lopez-Franco O, Muñoz-Garcia B, Egido J, Blanco-Colio LM, Martin-Ventura JL.

Cardiovasc Res. 2012 Jul 1;95(1):116-23. doi: 10.1093/cvr/cvs158. Epub 2012 Apr 30.


Akt2/LDLr double knockout mice display impaired glucose tolerance and develop more complex atherosclerotic plaques than LDLr knockout mice.

Rensing KL, de Jager SC, Stroes ES, Vos M, Twickler MT, Dallinga-Thie GM, de Vries CJ, Kuiper J, Bot I, von der Thüsen JH.

Cardiovasc Res. 2014 Feb 1;101(2):277-87. doi: 10.1093/cvr/cvt252. Epub 2013 Nov 12.


Vasoprotective effects of urocortin 1 against atherosclerosis in vitro and in vivo.

Hasegawa A, Sato K, Shirai R, Watanabe R, Yamamoto K, Watanabe K, Nohtomi K, Hirano T, Watanabe T.

PLoS One. 2014 Dec 2;9(12):e110866. doi: 10.1371/journal.pone.0110866. eCollection 2014.


TRAIL-deficiency accelerates vascular calcification in atherosclerosis via modulation of RANKL.

Di Bartolo BA, Cartland SP, Harith HH, Bobryshev YV, Schoppet M, Kavurma MM.

PLoS One. 2013 Sep 5;8(9):e74211. doi: 10.1371/journal.pone.0074211. eCollection 2013. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/9732ca63-7532-4b92-8d6e-65c0863f25aa.


Protocatechuic aldehyde inhibits migration and proliferation of vascular smooth muscle cells and intravascular thrombosis.

Moon CY, Ku CR, Cho YH, Lee EJ.

Biochem Biophys Res Commun. 2012 Jun 22;423(1):116-21. doi: 10.1016/j.bbrc.2012.05.092. Epub 2012 May 26.


Fibronectin extra domain A stabilises atherosclerotic plaques in apolipoprotein E and in LDL-receptor-deficient mice.

Pulakazhi Venu VK, Uboldi P, Dhyani A, Patrini A, Baetta R, Ferri N, Corsini A, Muro AF, Catapano AL, Norata GD.

Thromb Haemost. 2015 Jul;114(1):186-97. doi: 10.1160/TH14-09-0790. Epub 2015 Apr 16.


Genetic Evidence Supports a Major Role for Akt1 in VSMCs During Atherogenesis.

Rotllan N, Wanschel AC, Fernández-Hernando A, Salerno AG, Offermanns S, Sessa WC, Fernández-Hernando C.

Circ Res. 2015 May 22;116(11):1744-52. doi: 10.1161/CIRCRESAHA.116.305895. Epub 2015 Apr 13.


TLR 2 induces vascular smooth muscle cell migration through cAMP response element-binding protein-mediated interleukin-6 production.

Lee GL, Chang YW, Wu JY, Wu ML, Wu KK, Yet SF, Kuo CC.

Arterioscler Thromb Vasc Biol. 2012 Nov;32(11):2751-60. doi: 10.1161/ATVBAHA.112.300302. Epub 2012 Sep 20.


Heat shock protein 90 is a promising target for effective growth inhibition of gastrointestinal neuroendocrine tumors.

Gloesenkamp C, Nitzsche B, Lim AR, Normant E, Vosburgh E, Schrader M, Ocker M, Scherübl H, Höpfner M.

Int J Oncol. 2012 May;40(5):1659-67. doi: 10.3892/ijo.2012.1328. Epub 2012 Jan 10.


3,3'Diindolylmethane suppresses vascular smooth muscle cell phenotypic modulation and inhibits neointima formation after carotid injury.

Guan H, Zhu L, Fu M, Yang D, Tian S, Guo Y, Cui C, Wang L, Jiang H.

PLoS One. 2012;7(4):e34957. doi: 10.1371/journal.pone.0034957. Epub 2012 Apr 10.


Sodium tanshinone IIA silate inhibits high glucose-induced vascular smooth muscle cell proliferation and migration through activation of AMP-activated protein kinase.

Wu WY, Yan H, Wang XB, Gui YZ, Gao F, Tang XL, Qin YL, Su M, Chen T, Wang YP.

PLoS One. 2014 Apr 16;9(4):e94957. doi: 10.1371/journal.pone.0094957. eCollection 2014.

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