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Items: 1 to 20 of 84

1.

The TGF-alpha precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction.

Wong ST, Winchell LF, McCune BK, Earp HS, Teixidó J, Massagué J, Herman B, Lee DC.

Cell. 1989 Feb 10;56(3):495-506.

PMID:
2464440
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3.

Expression of the TGF alpha integral membrane precursor induces transformation of NRK cells.

Blasband AJ, Gilligan DM, Winchell LF, Wong ST, Luetteke NC, Rogers KT, Lee DC.

Oncogene. 1990 Aug;5(8):1213-21.

PMID:
2392325
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Transmembrane TGF-alpha precursors activate EGF/TGF-alpha receptors.

Brachmann R, Lindquist PB, Nagashima M, Kohr W, Lipari T, Napier M, Derynck R.

Cell. 1989 Feb 24;56(4):691-700.

PMID:
2645058
6.

Autocrine regulation of membrane transforming growth factor-alpha cleavage.

Baselga J, Mendelsohn J, Kim YM, Pandiella A.

J Biol Chem. 1996 Feb 9;271(6):3279-84.

8.

Transformation of NIH3T3 fibroblasts by an expression vector for the human epidermal growth factor precursor.

Heidaran MA, Fleming TP, Bottaro DP, Bell GI, Di Fiore PP, Aaronson SA.

Oncogene. 1990 Aug;5(8):1265-70.

PMID:
2392327
9.

A variant epidermal growth factor receptor exhibits altered type alpha transforming growth factor binding and transmembrane signaling.

Moriai T, Kobrin MS, Hope C, Speck L, Korc M.

Proc Natl Acad Sci U S A. 1994 Oct 11;91(21):10217-21.

10.

Cleavage of the membrane precursor for transforming growth factor alpha is a regulated process.

Pandiella A, Massagué J.

Proc Natl Acad Sci U S A. 1991 Mar 1;88(5):1726-30.

11.

Differential induction of phosphatidylcholine hydrolysis, diacylglycerol formation and protein kinase C activation by epidermal growth factor and transforming growth factor-alpha in normal human skin fibroblasts and keratinocytes.

Reynolds NJ, Talwar HS, Baldassare JJ, Henderson PA, Elder JT, Voorhees JJ, Fisher GJ.

Biochem J. 1993 Sep 1;294 ( Pt 2):535-44. Erratum in: Biochem J 1993 Nov 1;295(Pt 3):903.

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Defective cleavage of membrane bound TGFalpha leads to enhanced activation of the EGF receptor in malignant cells.

Yang H, Jiang D, Li W, Liang J, Gentry LE, Brattain MG.

Oncogene. 2000 Apr 6;19(15):1901-14.

17.

Integral membrane glycoprotein properties of the prohormone pro-transforming growth factor-alpha.

Teixidó J, Gilmore R, Lee DC, Massagué J.

Nature. 1987 Apr 30-May 6;326(6116):883-5.

PMID:
3574460
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