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Items: 1 to 20 of 166

1.

Cleavage within Reelin repeat 3 regulates the duration and range of the signaling activity of Reelin protein.

Koie M, Okumura K, Hisanaga A, Kamei T, Sasaki K, Deng M, Baba A, Kohno T, Hattori M.

J Biol Chem. 2014 May 2;289(18):12922-30. doi: 10.1074/jbc.M113.536326. Epub 2014 Mar 18.

2.

C-terminal region-dependent change of antibody-binding to the Eighth Reelin repeat reflects the signaling activity of Reelin.

Kohno T, Nakano Y, Kitoh N, Yagi H, Kato K, Baba A, Hattori M.

J Neurosci Res. 2009 Nov 1;87(14):3043-53. doi: 10.1002/jnr.22143.

PMID:
19530167
3.

Mechanism and significance of specific proteolytic cleavage of Reelin.

Kohno S, Kohno T, Nakano Y, Suzuki K, Ishii M, Tagami H, Baba A, Hattori M.

Biochem Biophys Res Commun. 2009 Feb 27;380(1):93-7. doi: 10.1016/j.bbrc.2009.01.039. Epub 2009 Jan 21.

PMID:
19166810
4.

Importance of Reelin C-terminal region in the development and maintenance of the postnatal cerebral cortex and its regulation by specific proteolysis.

Kohno T, Honda T, Kubo K, Nakano Y, Tsuchiya A, Murakami T, Banno H, Nakajima K, Hattori M.

J Neurosci. 2015 Mar 18;35(11):4776-87. doi: 10.1523/JNEUROSCI.4119-14.2015.

5.

Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin.

Ogino H, Hisanaga A, Kohno T, Kondo Y, Okumura K, Kamei T, Sato T, Asahara H, Tsuiji H, Fukata M, Hattori M.

J Neurosci. 2017 Mar 22;37(12):3181-3191. doi: 10.1523/JNEUROSCI.3632-16.2017. Epub 2017 Feb 17.

6.

The extremely conserved C-terminal region of Reelin is not necessary for secretion but is required for efficient activation of downstream signaling.

Nakano Y, Kohno T, Hibi T, Kohno S, Baba A, Mikoshiba K, Nakajima K, Hattori M.

J Biol Chem. 2007 Jul 13;282(28):20544-52. Epub 2007 May 15.

7.

Determination of cleavage site of Reelin between its sixth and seventh repeat and contribution of meprin metalloproteases to the cleavage.

Sato Y, Kobayashi D, Kohno T, Kidani Y, Prox J, Becker-Pauly C, Hattori M.

J Biochem. 2016 Mar;159(3):305-12. doi: 10.1093/jb/mvv102. Epub 2015 Oct 21.

PMID:
26491063
8.

Reelin secreted by GABAergic neurons regulates glutamate receptor homeostasis.

Campo CG, Sinagra M, Verrier D, Manzoni OJ, Chavis P.

PLoS One. 2009;4(5):e5505. doi: 10.1371/journal.pone.0005505. Epub 2009 May 11.

9.

Apolipoprotein E receptors are required for reelin-induced proteasomal degradation of the neuronal adaptor protein Disabled-1.

Bock HH, Jossin Y, May P, Bergner O, Herz J.

J Biol Chem. 2004 Aug 6;279(32):33471-9. Epub 2004 Jun 2.

10.

Re-evaluation of protease activity of reelin.

Kohno T, Hattori M.

Biol Pharm Bull. 2010;33(6):1047-9.

11.

ApoER2 processing by presenilin-1 modulates reelin expression.

Balmaceda V, Cuchillo-Ibáñez I, Pujadas L, García-Ayllón MS, Saura CA, Nimpf J, Soriano E, Sáez-Valero J.

FASEB J. 2014 Apr;28(4):1543-54. doi: 10.1096/fj.13-239350. Epub 2013 Dec 16.

PMID:
24344333
12.

A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4) cleaves Reelin in an isoform-dependent manner.

Hisanaga A, Morishita S, Suzuki K, Sasaki K, Koie M, Kohno T, Hattori M.

FEBS Lett. 2012 Sep 21;586(19):3349-53. doi: 10.1016/j.febslet.2012.07.017. Epub 2012 Jul 20.

13.

Splicing variations in the ligand-binding domain of ApoER2 results in functional differences in the binding properties to Reelin.

Hibi T, Mizutani M, Baba A, Hattori M.

Neurosci Res. 2009 Apr;63(4):251-8. doi: 10.1016/j.neures.2008.12.009. Epub 2009 Jan 9.

PMID:
19167437
14.

Modulation of Reelin signaling by Cyclin-dependent kinase 5.

Ohshima T, Suzuki H, Morimura T, Ogawa M, Mikoshiba K.

Brain Res. 2007 Apr 6;1140:84-95. Epub 2006 Mar 10.

PMID:
16529723
15.

VEGF activates NR2B phosphorylation through Dab1 pathway.

Howell KR, Hoda MN, Pillai A.

Neurosci Lett. 2013 Sep 27;552:30-4. doi: 10.1016/j.neulet.2013.07.032. Epub 2013 Jul 31.

16.

Reelin induces EphB activation.

Bouché E, Romero-Ortega MI, Henkemeyer M, Catchpole T, Leemhuis J, Frotscher M, May P, Herz J, Bock HH.

Cell Res. 2013 Apr;23(4):473-90. doi: 10.1038/cr.2013.7. Epub 2013 Jan 15.

17.

Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin α5β1.

Sekine K, Kawauchi T, Kubo K, Honda T, Herz J, Hattori M, Kinashi T, Nakajima K.

Neuron. 2012 Oct 18;76(2):353-69. doi: 10.1016/j.neuron.2012.07.020. Epub 2012 Oct 17.

18.
19.

Epileptiform activity interferes with proteolytic processing of Reelin required for dentate granule cell positioning.

Tinnes S, Schäfer MK, Flubacher A, Münzner G, Frotscher M, Haas CA.

FASEB J. 2011 Mar;25(3):1002-13. doi: 10.1096/fj.10-168294. Epub 2010 Dec 8.

PMID:
21148112
20.

Downregulation of functional Reelin receptors in projection neurons implies that primary Reelin action occurs at early/premigratory stages.

Uchida T, Baba A, Pérez-Martínez FJ, Hibi T, Miyata T, Luque JM, Nakajima K, Hattori M.

J Neurosci. 2009 Aug 26;29(34):10653-62. doi: 10.1523/JNEUROSCI.0345-09.2009.

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