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Items: 1 to 20 of 126

1.

LKB1/AMPK and PKA control ABCB11 trafficking and polarization in hepatocytes.

Homolya L, Fu D, Sengupta P, Jarnik M, Gillet JP, Vitale-Cross L, Gutkind JS, Lippincott-Schwartz J, Arias IM.

PLoS One. 2014 Mar 18;9(3):e91921. doi: 10.1371/journal.pone.0091921. eCollection 2014.

2.

Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway.

Fu D, Wakabayashi Y, Lippincott-Schwartz J, Arias IM.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1403-8. doi: 10.1073/pnas.1018376108. Epub 2011 Jan 10.

3.

Rab11a and myosin Vb are required for bile canalicular formation in WIF-B9 cells.

Wakabayashi Y, Dutt P, Lippincott-Schwartz J, Arias IM.

Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15087-92. Epub 2005 Oct 7.

4.

Transporters on demand: intrahepatic pools of canalicular ATP binding cassette transporters in rat liver.

Kipp H, Pichetshote N, Arias IM.

J Biol Chem. 2001 Mar 9;276(10):7218-24. Epub 2000 Dec 11.

5.
6.

Regulation of bile canalicular network formation and maintenance by AMP-activated protein kinase and LKB1.

Fu D, Wakabayashi Y, Ido Y, Lippincott-Schwartz J, Arias IM.

J Cell Sci. 2010 Oct 1;123(Pt 19):3294-302. doi: 10.1242/jcs.068098. Epub 2010 Sep 7.

7.

Prevention of estradiol 17beta-D-glucuronide-induced canalicular transporter internalization by hormonal modulation of cAMP in rat hepatocytes.

Zucchetti AE, Barosso IR, Boaglio A, Pellegrino JM, Ochoa EJ, Roma MG, Crocenzi FA, Sánchez Pozzi EJ.

Mol Biol Cell. 2011 Oct;22(20):3902-15. doi: 10.1091/mbc.E11-01-0047. Epub 2011 Aug 24.

8.

Role of AMP-activated protein kinase α1 in 17α-ethinylestradiol-induced cholestasis in rats.

Li X, Liu R, Luo L, Yu L, Chen X, Sun L, Wang T, Hylemon PB, Zhou H, Jiang Z, Zhang L.

Arch Toxicol. 2017 Jan;91(1):481-494. doi: 10.1007/s00204-016-1697-8. Epub 2016 Apr 18.

PMID:
27090119
10.

Mechanisms by which cAMP increases bile acid secretion in rat liver and canalicular membrane vesicles.

Misra S, Varticovski L, Arias IM.

Am J Physiol Gastrointest Liver Physiol. 2003 Aug;285(2):G316-24. Epub 2003 Apr 17.

11.

Liver kinase B1 regulates hepatocellular tight junction distribution and function in vivo.

Porat-Shliom N, Tietgens AJ, Van Itallie CM, Vitale-Cross L, Jarnik M, Harding OJ, Anderson JM, Gutkind JS, Weigert R, Arias IM.

Hepatology. 2016 Oct;64(4):1317-29. doi: 10.1002/hep.28724. Epub 2016 Jul 28.

12.

Intracellular trafficking and regulation of canalicular ATP-binding cassette transporters.

Kipp H, Arias IM.

Semin Liver Dis. 2000;20(3):339-51. Review.

PMID:
11076400
13.

Efficient trafficking of MDR1/P-glycoprotein to apical canalicular plasma membranes in HepG2 cells requires PKA-RIIalpha anchoring and glucosylceramide.

Wojtal KA, de Vries E, Hoekstra D, van Ijzendoorn SC.

Mol Biol Cell. 2006 Aug;17(8):3638-50. Epub 2006 May 24.

16.

Bile acid transport in sister of P-glycoprotein (ABCB11) knockout mice.

Lam P, Wang R, Ling V.

Biochemistry. 2005 Sep 20;44(37):12598-605.

PMID:
16156672
17.

LKB1 is required for hepatic bile acid transport and canalicular membrane integrity in mice.

Woods A, Heslegrave AJ, Muckett PJ, Levene AP, Clements M, Mobberley M, Ryder TA, Abu-Hayyeh S, Williamson C, Goldin RD, Ashworth A, Withers DJ, Carling D.

Biochem J. 2011 Feb 15;434(1):49-60. doi: 10.1042/BJ20101721.

18.

Hormonal modulation of hepatic cAMP prevents estradiol 17β-D-glucuronide-induced cholestasis in perfused rat liver.

Zucchetti AE, Barosso IR, Boaglio AC, Luquita MG, Roma MG, Crocenzi FA, Sánchez Pozzi EJ.

Dig Dis Sci. 2013 Jun;58(6):1602-14. doi: 10.1007/s10620-013-2558-4. Epub 2013 Jan 31.

PMID:
23371010
19.
20.

AKAP350 Is involved in the development of apical "canalicular" structures in hepatic cells HepG2.

Mattaloni SM, Kolobova E, Favre C, Marinelli RA, Goldenring JR, Larocca MC.

J Cell Physiol. 2012 Jan;227(1):160-71. doi: 10.1002/jcp.22713.

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