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Contribution of eukaryotic-type serine/threonine kinase to stress response and virulence of Streptococcus suis.

Zhu H, Zhou J, Ni Y, Yu Z, Mao A, Hu Y, Wang W, Zhang X, Wen L, Li B, Wang X, Yu Y, Lv L, Guo R, Lu C, He K.

PLoS One. 2014 Mar 17;9(3):e91971. doi: 10.1371/journal.pone.0091971. eCollection 2014.


The novel virulence-related gene stp of Streptococcus suis serotype 9 strain contributes to a significant reduction in mouse mortality.

Zhu H, Huang D, Zhang W, Wu Z, Lu Y, Jia H, Wang M, Lu C.

Microb Pathog. 2011 Dec;51(6):442-53. doi: 10.1016/j.micpath.2011.08.002. Epub 2011 Sep 10.


Trigger factor of Streptococcus suis is involved in stress tolerance and virulence.

Wu T, Zhao Z, Zhang L, Ma H, Lu K, Ren W, Liu Z, Chang H, Bei W, Qiu Y, Chen H.

Microb Pathog. 2011 Jul-Aug;51(1-2):69-76. doi: 10.1016/j.micpath.2010.10.001. Epub 2010 Nov 18.


Functional analysis of c-di-AMP phosphodiesterase, GdpP, in Streptococcus suis serotype 2.

Du B, Ji W, An H, Shi Y, Huang Q, Cheng Y, Fu Q, Wang H, Yan Y, Sun J.

Microbiol Res. 2014 Sep-Oct;169(9-10):749-58. doi: 10.1016/j.micres.2014.01.002. Epub 2014 Jan 26.


Effect of Tran on virulence through regulating metabolism and stress tolerance of Streptococcus suis serotype 2.

Li Y, Zheng JX, Zhang H, Fan HJ, Lu CP.

Microbiol Res. 2014 Sep-Oct;169(9-10):666-74. doi: 10.1016/j.micres.2014.03.002. Epub 2014 Mar 29.


The orphan response regulator RevSC21 controls the attachment of Streptococcus suis serotype-2 to human laryngeal epithelial cells and the expression of virulence genes.

Wu T, Chang H, Tan C, Bei W, Chen H.

FEMS Microbiol Lett. 2009 Mar;292(2):170-81. doi: 10.1111/j.1574-6968.2008.01486.x. Epub 2009 Feb 5.


The two-component regulatory system CiaRH contributes to the virulence of Streptococcus suis 2.

Li J, Tan C, Zhou Y, Fu S, Hu L, Hu J, Chen H, Bei W.

Vet Microbiol. 2011 Feb 24;148(1):99-104. doi: 10.1016/j.vetmic.2010.08.005. Epub 2010 Aug 17.


The two-component system Ihk/Irr contributes to the virulence of Streptococcus suis serotype 2 strain 05ZYH33 through alteration of the bacterial cell metabolism.

Han H, Liu C, Wang Q, Xuan C, Zheng B, Tang J, Yan J, Zhang J, Li M, Cheng H, Lu G, Gao GF.

Microbiology. 2012 Jul;158(Pt 7):1852-66. doi: 10.1099/mic.0.057448-0. Epub 2012 Apr 13.


The orphan response regulator CovR: a globally negative modulator of virulence in Streptococcus suis serotype 2.

Pan X, Ge J, Li M, Wu B, Wang C, Wang J, Feng Y, Yin Z, Zheng F, Cheng G, Sun W, Ji H, Hu D, Shi P, Feng X, Hao X, Dong R, Hu F, Tang J.

J Bacteriol. 2009 Apr;191(8):2601-12. doi: 10.1128/JB.01309-08. Epub 2009 Jan 30.


Contribution of the Rgg transcription regulator to metabolism and virulence of Streptococcus suis serotype 2.

Zheng F, Ji H, Cao M, Wang C, Feng Y, Li M, Pan X, Wang J, Qin Y, Hu F, Tang J.

Infect Immun. 2011 Mar;79(3):1319-28. doi: 10.1128/IAI.00193-10. Epub 2010 Dec 13.


Functional definition of LuxS, an autoinducer-2 (AI-2) synthase and its role in full virulence of Streptococcus suis serotype 2.

Cao M, Feng Y, Wang C, Zheng F, Li M, Liao H, Mao Y, Pan X, Wang J, Hu D, Hu F, Tang J.

J Microbiol. 2011 Dec;49(6):1000-11. doi: 10.1007/s12275-011-1523-1. Epub 2011 Dec 28.


The involvement of sortase A in high virulence of STSS-causing Streptococcus suis serotype 2.

Wang C, Li M, Feng Y, Zheng F, Dong Y, Pan X, Cheng G, Dong R, Hu D, Feng X, Ge J, Liu D, Wang J, Cao M, Hu F, Tang J.

Arch Microbiol. 2009 Jan;191(1):23-33. doi: 10.1007/s00203-008-0425-z. Epub 2008 Aug 21.


A Fur-like protein PerR regulates two oxidative stress response related operons dpr and metQIN in Streptococcus suis.

Zhang T, Ding Y, Li T, Wan Y, Li W, Chen H, Zhou R.

BMC Microbiol. 2012 May 30;12:85.


Disruption of srtA gene in Streptococcus suis results in decreased interactions with endothelial cells and extracellular matrix proteins.

Vanier G, Sekizaki T, Domínguez-Punaro MC, Esgleas M, Osaki M, Takamatsu D, Segura M, Gottschalk M.

Vet Microbiol. 2008 Mar 18;127(3-4):417-24. Epub 2007 Sep 18.


SsPep contributes to the virulence of Streptococcus suis.

Tan C, Liu M, Li J, Jin M, Bei W, Chen H.

Microb Pathog. 2011 Nov;51(5):319-24. doi: 10.1016/j.micpath.2011.07.008. Epub 2011 Aug 5.


Inactivation of the sodA gene of Streptococcus suis type 2 encoding superoxide dismutase leads to reduced virulence to mice.

Tang Y, Zhang X, Wu W, Lu Z, Fang W.

Vet Microbiol. 2012 Aug 17;158(3-4):360-6. doi: 10.1016/j.vetmic.2012.02.028. Epub 2012 Feb 28.


New putative virulence factors of Streptococcus suis involved in invasion of porcine brain microvascular endothelial cells.

Vanier G, Fittipaldi N, Slater JD, de la Cruz Domínguez-Punaro M, Rycroft AN, Segura M, Maskell DJ, Gottschalk M.

Microb Pathog. 2009 Jan;46(1):13-20. doi: 10.1016/j.micpath.2008.10.003. Epub 2008 Oct 17.


IgA1 protease contributes to the virulence of Streptococcus suis.

Zhang A, Mu X, Chen B, Han L, Chen H, Jin M.

Vet Microbiol. 2011 Mar 24;148(2-4):436-9. doi: 10.1016/j.vetmic.2010.09.027. Epub 2010 Oct 30.


The cation-uptake regulators AdcR and Fur are necessary for full virulence of Streptococcus suis.

Aranda J, Garrido ME, Fittipaldi N, Cortés P, Llagostera M, Gottschalk M, Barbé J.

Vet Microbiol. 2010 Jul 29;144(1-2):246-9. doi: 10.1016/j.vetmic.2009.12.037. Epub 2010 Jan 11.


Streptococcus suis type 2 SSU0587 protein is a beta-galactosidase that contributes to bacterial adhesion but not to virulence in mice.

Tang Y, Zhang X, Yin Y, Hardwidge PR, Fang W.

J Vet Med Sci. 2014 Jul;76(7):1055-9. Epub 2014 Mar 27.

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