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Items: 1 to 20 of 141

1.

Saikosaponin D acts against corticosterone-induced apoptosis via regulation of mitochondrial GR translocation and a GR-dependent pathway.

Li ZY, Jiang YM, Liu YM, Guo Z, Shen SN, Liu XM, Pan RL.

Prog Neuropsychopharmacol Biol Psychiatry. 2014 Aug 4;53:80-9. doi: 10.1016/j.pnpbp.2014.02.010. Epub 2014 Mar 15.

PMID:
24636912
2.

Neuroprotective effects of total saikosaponins of Bupleurum yinchowense on corticosterone-induced apoptosis in PC12 cells.

Li ZY, Guo Z, Liu YM, Liu XM, Chang Q, Liao YH, Pan RL.

J Ethnopharmacol. 2013 Jul 30;148(3):794-803. doi: 10.1016/j.jep.2013.04.057. Epub 2013 May 18.

3.

Neuroprotective effect of water extract of Panax ginseng on corticosterone-induced apoptosis in PC12 cells and its underlying molecule mechanisms.

Jiang Y, Li Z, Liu Y, Liu X, Chang Q, Liao Y, Pan R.

J Ethnopharmacol. 2015 Jan 15;159:102-12. doi: 10.1016/j.jep.2014.10.062. Epub 2014 Nov 15.

PMID:
25446601
4.

HPOB, an HDAC6 inhibitor, attenuates corticosterone-induced injury in rat adrenal pheochromocytoma PC12 cells by inhibiting mitochondrial GR translocation and the intrinsic apoptosis pathway.

Li ZY, Li QZ, Chen L, Chen BD, Zhang C, Wang X, Li WP.

Neurochem Int. 2016 Oct;99:239-251. doi: 10.1016/j.neuint.2016.08.004. Epub 2016 Aug 12.

PMID:
27522966
5.

Saikosaponin D disrupts platelet-derived growth factor-β receptor/p38 pathway leading to mitochondrial apoptosis in human LO2 hepatocyte cells: a potential mechanism of hepatotoxicity.

Chen L, Zhang F, Kong D, Zhu X, Chen W, Wang A, Zheng S.

Chem Biol Interact. 2013 Oct 25;206(1):76-82. doi: 10.1016/j.cbi.2013.08.006. Epub 2013 Aug 28.

PMID:
23994742
6.
7.

Saikosaponin a inhibits the proliferation and activation of T cells through cell cycle arrest and induction of apoptosis.

Sun Y, Cai TT, Zhou XB, Xu Q.

Int Immunopharmacol. 2009 Jul;9(7-8):978-83. doi: 10.1016/j.intimp.2009.04.006. Epub 2009 Apr 16.

PMID:
19375524
8.

Cajaninstilbene acid prevents corticosterone-induced apoptosis in PC12 cells by inhibiting the mitochondrial apoptotic pathway.

Jiang BP, Liu YM, Le L, Li ZY, Si JY, Liu XM, Chang Q, Pan RL.

Cell Physiol Biochem. 2014;34(3):1015-26. doi: 10.1159/000366317. Epub 2014 Sep 1.

9.

Saikosaponin d induces cell death through caspase-3-dependent, caspase-3-independent and mitochondrial pathways in mammalian hepatic stellate cells.

Chen MF, Huang SJ, Huang CC, Liu PS, Lin KI, Liu CW, Hsieh WC, Shiu LY, Chen CH.

BMC Cancer. 2016 Jul 26;16:532. doi: 10.1186/s12885-016-2599-0.

10.

Inhibitory Effect of Lychee Seed Saponins on Apoptosis Induced by Aβ25-35 through Regulation of the Apoptotic and NF-κB Pathways in PC12 Cells.

Wang X, Zhang H, Liu J, Chen R, Tang Y, Chen H, Gu L, Li M, Cao S, Qin D, Wu J.

Nutrients. 2017 Mar 29;9(4). pii: E337. doi: 10.3390/nu9040337.

12.

[Saikosaponin-d up-regulates GR mRNA expression and induces apoptosis in HL-60 cells].

Bu S, Xu J, Sun J.

Zhonghua Xue Ye Xue Za Zhi. 1999 Jul;20(7):354-6. Chinese.

PMID:
11721431
13.

Saikosaponin a and its epimer saikosaponin d exhibit anti-inflammatory activity by suppressing activation of NF-κB signaling pathway.

Lu CN, Yuan ZG, Zhang XL, Yan R, Zhao YQ, Liao M, Chen JX.

Int Immunopharmacol. 2012 Sep;14(1):121-6. doi: 10.1016/j.intimp.2012.06.010. Epub 2012 Jun 21.

PMID:
22728095
14.

[Effect of Saikosaponin-d on up-regulating GR mRNA expression and inhibiting cell growth in human leukemia cells].

Bu S, Xu J, Sun J.

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2000 May;20(5):350-2. Chinese.

PMID:
11789246
15.

Corchorusin-D, a saikosaponin-like compound isolated from Corchorus acutangulus Lam., targets mitochondrial apoptotic pathways in leukemic cell lines (HL-60 and U937).

Mallick S, Ghosh P, Samanta SK, Kinra S, Pal BC, Gomes A, Vedasiromoni JR.

Cancer Chemother Pharmacol. 2010 Sep;66(4):709-19. doi: 10.1007/s00280-009-1214-3. Epub 2009 Dec 24.

PMID:
20033811
16.

Anti-melanoma activity of Bupleurum chinense, Bupleurum kaoi and nanoparticle formulation of their major bioactive compound saikosaponin-d.

Hu SC, Lee IT, Yen MH, Lin CC, Lee CW, Yen FL.

J Ethnopharmacol. 2016 Feb 17;179:432-42. doi: 10.1016/j.jep.2015.12.058. Epub 2015 Dec 31.

PMID:
26748071
17.

Effect of corchorusin-D, a saikosaponin like compound, on B16F10 melanoma cells (in vitro and in vivo).

Mallick S, Pal BC, Kumar D, Chatterjee N, Das S, Saha KD.

J Asian Nat Prod Res. 2013 Nov;15(11):1197-203. doi: 10.1080/10286020.2013.837451. Epub 2013 Nov 11.

PMID:
24215510
18.

Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells.

Chantong B, Kratschmar DV, Nashev LG, Balazs Z, Odermatt A.

J Neuroinflammation. 2012 Nov 28;9:260. doi: 10.1186/1742-2094-9-260.

19.

Resveratrol protects PC12 cells against OGD/ R-induced apoptosis via the mitochondrial-mediated signaling pathway.

Liu X, Zhu X, Chen M, Ge Q, Shen Y, Pan S.

Acta Biochim Biophys Sin (Shanghai). 2016 Apr;48(4):342-53. doi: 10.1093/abbs/gmw011.

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