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Items: 1 to 20 of 138

1.

Trimethylation of histone H3 lysine 36 by human methyltransferase PRDM9 protein.

Eram MS, Bustos SP, Lima-Fernandes E, Siarheyeva A, Senisterra G, Hajian T, Chau I, Duan S, Wu H, Dombrovski L, Schapira M, Arrowsmith CH, Vedadi M.

J Biol Chem. 2014 Apr 25;289(17):12177-88. doi: 10.1074/jbc.M113.523183. Epub 2014 Mar 14.

2.

The Meiotic Recombination Activator PRDM9 Trimethylates Both H3K36 and H3K4 at Recombination Hotspots In Vivo.

Powers NR, Parvanov ED, Baker CL, Walker M, Petkov PM, Paigen K.

PLoS Genet. 2016 Jun 30;12(6):e1006146. doi: 10.1371/journal.pgen.1006146. eCollection 2016 Jun.

3.

PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 Trimethyltransferase.

Blazer LL, Lima-Fernandes E, Gibson E, Eram MS, Loppnau P, Arrowsmith CH, Schapira M, Vedadi M.

J Biol Chem. 2016 Jun 24;291(26):13509-19. doi: 10.1074/jbc.M116.721472. Epub 2016 Apr 29.

4.

Molecular basis for the regulation of the H3K4 methyltransferase activity of PRDM9.

Wu H, Mathioudakis N, Diagouraga B, Dong A, Dombrovski L, Baudat F, Cusack S, de Massy B, Kadlec J.

Cell Rep. 2013 Oct 17;5(1):13-20. doi: 10.1016/j.celrep.2013.08.035. Epub 2013 Oct 3.

5.

Genetic recombination is directed away from functional genomic elements in mice.

Brick K, Smagulova F, Khil P, Camerini-Otero RD, Petukhova GV.

Nature. 2012 May 13;485(7400):642-5. doi: 10.1038/nature11089.

6.

Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.

Patel A, Vought VE, Swatkoski S, Viggiano S, Howard B, Dharmarajan V, Monteith KE, Kupakuwana G, Namitz KE, Shinsky SA, Cotter RJ, Cosgrove MS.

J Biol Chem. 2014 Jan 10;289(2):868-84. doi: 10.1074/jbc.M113.501064. Epub 2013 Nov 14.

7.

Mouse PRDM9 DNA-binding specificity determines sites of histone H3 lysine 4 trimethylation for initiation of meiotic recombination.

Grey C, Barthès P, Chauveau-Le Friec G, Langa F, Baudat F, de Massy B.

PLoS Biol. 2011 Oct;9(10):e1001176. doi: 10.1371/journal.pbio.1001176. Epub 2011 Oct 18.

8.

Histone H3K27 trimethylation inhibits H3 binding and function of SET1-like H3K4 methyltransferase complexes.

Kim DH, Tang Z, Shimada M, Fierz B, Houck-Loomis B, Bar-Dagen M, Lee S, Lee SK, Muir TW, Roeder RG, Lee JW.

Mol Cell Biol. 2013 Dec;33(24):4936-46. doi: 10.1128/MCB.00601-13. Epub 2013 Oct 14.

9.

In vitro histone lysine methylation by NSD1, NSD2/MMSET/WHSC1 and NSD3/WHSC1L.

Morishita M, Mevius D, di Luccio E.

BMC Struct Biol. 2014 Dec 12;14:25. doi: 10.1186/s12900-014-0025-x.

10.

Preferential dimethylation of histone H4 lysine 20 by Suv4-20.

Yang H, Pesavento JJ, Starnes TW, Cryderman DE, Wallrath LL, Kelleher NL, Mizzen CA.

J Biol Chem. 2008 May 2;283(18):12085-92. doi: 10.1074/jbc.M707974200. Epub 2008 Feb 21.

11.

A histone H3 methyltransferase controls epigenetic events required for meiotic prophase.

Hayashi K, Yoshida K, Matsui Y.

Nature. 2005 Nov 17;438(7066):374-8.

PMID:
16292313
12.

Kinetic characterization of human histone H3 lysine 36 methyltransferases, ASH1L and SETD2.

Eram MS, Kuznetsova E, Li F, Lima-Fernandes E, Kennedy S, Chau I, Arrowsmith CH, Schapira M, Vedadi M.

Biochim Biophys Acta. 2015 Sep;1850(9):1842-8. doi: 10.1016/j.bbagen.2015.05.013. Epub 2015 May 19.

PMID:
26002201
13.

Di- and tri- but not monomethylation on histone H3 lysine 36 marks active transcription of genes involved in flowering time regulation and other processes in Arabidopsis thaliana.

Xu L, Zhao Z, Dong A, Soubigou-Taconnat L, Renou JP, Steinmetz A, Shen WH.

Mol Cell Biol. 2008 Feb;28(4):1348-60. Epub 2007 Dec 10.

14.

Quantitative proteomics reveals that the specific methyltransferases Txr1p and Ezl2p differentially affect the mono-, di- and trimethylation states of histone H3 lysine 27 (H3K27).

Zhang C, Molascon AJ, Gao S, Liu Y, Andrews PC.

Mol Cell Proteomics. 2013 Jun;12(6):1678-88. doi: 10.1074/mcp.M112.021733. Epub 2012 Nov 13.

15.

Substrate specificity and kinetic mechanism of mammalian G9a histone H3 methyltransferase.

Patnaik D, Chin HG, Estève PO, Benner J, Jacobsen SE, Pradhan S.

J Biol Chem. 2004 Dec 17;279(51):53248-58. Epub 2004 Oct 14.

16.

The RNA polymerase II kinase Ctk1 regulates positioning of a 5' histone methylation boundary along genes.

Xiao T, Shibata Y, Rao B, Laribee RN, O'Rourke R, Buck MJ, Greenblatt JF, Krogan NJ, Lieb JD, Strahl BD.

Mol Cell Biol. 2007 Jan;27(2):721-31. Epub 2006 Nov 6.

17.

Structural basis for human PRDM9 action at recombination hot spots.

Patel A, Horton JR, Wilson GG, Zhang X, Cheng X.

Genes Dev. 2016 Feb 1;30(3):257-65. doi: 10.1101/gad.274928.115.

18.

On your histone mark, SET, methylate!

Binda O.

Epigenetics. 2013 May;8(5):457-63. doi: 10.4161/epi.24451. Epub 2013 Apr 27. Review.

19.

On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.

Patel A, Dharmarajan V, Vought VE, Cosgrove MS.

J Biol Chem. 2009 Sep 4;284(36):24242-56. doi: 10.1074/jbc.M109.014498. Epub 2009 Jun 25.

20.

Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans.

Greer EL, Maures TJ, Hauswirth AG, Green EM, Leeman DS, Maro GS, Han S, Banko MR, Gozani O, Brunet A.

Nature. 2010 Jul 15;466(7304):383-7. doi: 10.1038/nature09195. Epub 2010 Jun 16.

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