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Items: 1 to 20 of 93

1.

A fundamental trade-off in covalent switching and its circumvention by enzyme bifunctionality in glucose homeostasis.

Dasgupta T, Croll DH, Owen JA, Vander Heiden MG, Locasale JW, Alon U, Cantley LC, Gunawardena J.

J Biol Chem. 2014 May 9;289(19):13010-25. doi: 10.1074/jbc.M113.546515. Epub 2014 Mar 14.

3.

Molecular coordination of hepatic glucose metabolism by the 6-phosphofructo-2-kinase/fructose-2,6- bisphosphatase:glucokinase complex.

Smith WE, Langer S, Wu C, Baltrusch S, Okar DA.

Mol Endocrinol. 2007 Jun;21(6):1478-87. Epub 2007 Mar 20.

PMID:
17374851
4.

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis.

Rider MH, Bertrand L, Vertommen D, Michels PA, Rousseau GG, Hue L.

Biochem J. 2004 Aug 1;381(Pt 3):561-79. Review.

5.

Endogenous activation of glucokinase by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase is glucose dependent.

Langer S, Kaminski MT, Lenzen S, Baltrusch S.

Mol Endocrinol. 2010 Oct;24(10):1988-97. doi: 10.1210/me.2010-0115. Epub 2010 Aug 11.

6.

Improved metabolic stimulus for glucose-induced insulin secretion through GK and PFK-2/FBPase-2 coexpression in insulin-producing RINm5F cells.

Baltrusch S, Langer S, Massa L, Tiedge M, Lenzen S.

Endocrinology. 2006 Dec;147(12):5768-76. Epub 2006 Sep 15.

PMID:
16980436
7.

Adenovirus-mediated overexpression of liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in gluconeogenic rat hepatoma cells. Paradoxical effect on Fru-2,6-P2 levels.

Argaud D, Lange AJ, Becker TC, Okar DA, el-Maghrabi MR, Newgard CB, Pilkis SJ.

J Biol Chem. 1995 Oct 13;270(41):24229-36.

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Dimer interface rearrangement of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase rat liver isoenzyme by cAMP-dependent Ser-32 phosphorylation.

Langer S, Okar DA, Schultz J, Lenzen S, Baltrusch S.

FEBS Lett. 2012 May 21;586(10):1419-25. doi: 10.1016/j.febslet.2012.03.066.

12.

Additive activation of glucokinase by the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and the chemical activator LY2121260.

Baltrusch S, Schmitt H, Brix A, Langer S, Lenzen S.

Biochem Pharmacol. 2012 May 1;83(9):1300-6. doi: 10.1016/j.bcp.2012.01.020. Epub 2012 Jan 24.

PMID:
22305745
13.

Role of the N-terminal region in covalent modification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: comparison of phosphorylation and ADP-ribosylation.

Rosa JL, PĂ©rez JX, Ventura F, Tauler A, Gil J, Shimoyama M, Pilkis SJ, Bartrons R.

Biochem J. 1995 Jul 1;309 ( Pt 1):119-25.

14.

Fructose-2,6-bisphosphate in control of hepatic gluconeogenesis. From metabolites to molecular genetics.

Pilkis SJ, el-Maghrabi MR, Claus TH.

Diabetes Care. 1990 Jun;13(6):582-99. Review. Erratum in: Diabetes Care 1990 Oct;13(10):1098.

PMID:
2162755
16.

A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic beta-cells.

Arden C, Hampson LJ, Huang GC, Shaw JA, Aldibbiat A, Holliman G, Manas D, Khan S, Lange AJ, Agius L.

Biochem J. 2008 Apr 1;411(1):41-51.

PMID:
18039179
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Tissue-specific structure/function differentiation of the liver isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

Lee YH, Li Y, Uyeda K, Hasemann CA.

J Biol Chem. 2003 Jan 3;278(1):523-30. Epub 2002 Oct 11.

20.

Rat hepatic 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase: a unique bifunctional enzyme.

Pilkis SJ, Chrisman T, Burgress B, McGrane M, Colosia A, Pilkis J, Claus TH, el-Maghrabi MR.

Adv Enzyme Regul. 1983;21:147-73.

PMID:
6100582

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