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Items: 1 to 20 of 196

1.

DNA methylation and body-mass index: a genome-wide analysis.

Dick KJ, Nelson CP, Tsaprouni L, Sandling JK, Aïssi D, Wahl S, Meduri E, Morange PE, Gagnon F, Grallert H, Waldenberger M, Peters A, Erdmann J, Hengstenberg C, Cambien F, Goodall AH, Ouwehand WH, Schunkert H, Thompson JR, Spector TD, Gieger C, Trégouët DA, Deloukas P, Samani NJ.

Lancet. 2014 Jun 7;383(9933):1990-8. doi: 10.1016/S0140-6736(13)62674-4. Epub 2014 Mar 13.

2.

Hypoxia-inducible factor 3A gene expression and methylation in adipose tissue is related to adipose tissue dysfunction.

Pfeiffer S, Krüger J, Maierhofer A, Böttcher Y, Klöting N, El Hajj N, Schleinitz D, Schön MR, Dietrich A, Fasshauer M, Lohmann T, Dreßler M, Stumvoll M, Haaf T, Blüher M, Kovacs P.

Sci Rep. 2016 Jun 27;6:27969. doi: 10.1038/srep27969.

3.

Positive correlation of cg16672562 methylation with obesity-related traits in childhood obesity, and its independence with underlying HIF3A (hypoxia-inducible factor 3a) genetic background.

Lee S, Kim HJ, Han S, Jeon JP, Park SI, Yu HY, Hwang MY, Lee J.

Oncotarget. 2017 Jun 27;8(40):67473-67481. doi: 10.18632/oncotarget.18707. eCollection 2017 Sep 15.

4.

DNA Methylation Variants at HIF3A Locus, B-Vitamin Intake, and Long-term Weight Change: Gene-Diet Interactions in Two U.S. Cohorts.

Huang T, Zheng Y, Qi Q, Xu M, Ley SH, Li Y, Kang JH, Wiggs J, Pasquale LR, Chan AT, Rimm EB, Hunter DJ, Manson JE, Willett WC, Hu FB, Qi L.

Diabetes. 2015 Sep;64(9):3146-54. doi: 10.2337/db15-0264. Epub 2015 May 22.

5.

Interaction between obesity and the Hypoxia Inducible Factor 3 Alpha Subunit rs3826795 polymorphism in relation with plasma alanine aminotransferase.

Wang S, Song J, Yang Y, Zhang Y, Chawla NV, Ma J, Wang H.

BMC Med Genet. 2017 Jul 28;18(1):80. doi: 10.1186/s12881-017-0437-0.

6.

DNA methylation and gene expression of HIF3A: cross-tissue validation and associations with BMI and insulin resistance.

Main AM, Gillberg L, Jacobsen AL, Nilsson E, Gjesing AP, Hansen T, Pedersen O, Ribel-Madsen R, Vaag A.

Clin Epigenetics. 2016 Sep 2;8:89. doi: 10.1186/s13148-016-0258-6. eCollection 2016.

7.

Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci.

Demerath EW, Guan W, Grove ML, Aslibekyan S, Mendelson M, Zhou YH, Hedman ÅK, Sandling JK, Li LA, Irvin MR, Zhi D, Deloukas P, Liang L, Liu C, Bressler J, Spector TD, North K, Li Y, Absher DM, Levy D, Arnett DK, Fornage M, Pankow JS, Boerwinkle E.

Hum Mol Genet. 2015 Aug 1;24(15):4464-79. doi: 10.1093/hmg/ddv161. Epub 2015 May 1.

8.

An epigenome-wide study of body mass index and DNA methylation in blood using participants from the Sister Study cohort.

Wilson LE, Harlid S, Xu Z, Sandler DP, Taylor JA.

Int J Obes (Lond). 2017 Jan;41(1):194-199. doi: 10.1038/ijo.2016.184. Epub 2016 Oct 24.

9.

A Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits.

Volkov P, Olsson AH, Gillberg L, Jørgensen SW, Brøns C, Eriksson KF, Groop L, Jansson PA, Nilsson E, Rönn T, Vaag A, Ling C.

PLoS One. 2016 Jun 20;11(6):e0157776. doi: 10.1371/journal.pone.0157776. eCollection 2016.

10.

HIF3A DNA Methylation Is Associated with Childhood Obesity and ALT.

Wang S, Song J, Yang Y, Zhang Y, Wang H, Ma J.

PLoS One. 2015 Dec 30;10(12):e0145944. doi: 10.1371/journal.pone.0145944. eCollection 2015.

11.

Epigenome-wide profiling of DNA methylation in paired samples of adipose tissue and blood.

Huang YT, Chu S, Loucks EB, Lin CL, Eaton CB, Buka SL, Kelsey KT.

Epigenetics. 2016 Mar 3;11(3):227-36. doi: 10.1080/15592294.2016.1146853. Epub 2016 Feb 18.

12.

Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood.

Rönn T, Volkov P, Gillberg L, Kokosar M, Perfilyev A, Jacobsen AL, Jørgensen SW, Brøns C, Jansson PA, Eriksson KF, Pedersen O, Hansen T, Groop L, Stener-Victorin E, Vaag A, Nilsson E, Ling C.

Hum Mol Genet. 2015 Jul 1;24(13):3792-813. doi: 10.1093/hmg/ddv124. Epub 2015 Apr 10.

PMID:
25861810
13.

Body mass index associated with genome-wide methylation in breast tissue.

Hair BY, Xu Z, Kirk EL, Harlid S, Sandhu R, Robinson WR, Wu MC, Olshan AF, Conway K, Taylor JA, Troester MA.

Breast Cancer Res Treat. 2015 Jun;151(2):453-63. doi: 10.1007/s10549-015-3401-8. Epub 2015 May 8.

14.

Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference.

Aslibekyan S, Demerath EW, Mendelson M, Zhi D, Guan W, Liang L, Sha J, Pankow JS, Liu C, Irvin MR, Fornage M, Hidalgo B, Lin LA, Thibeault KS, Bressler J, Tsai MY, Grove ML, Hopkins PN, Boerwinkle E, Borecki IB, Ordovas JM, Levy D, Tiwari HK, Absher DM, Arnett DK.

Obesity (Silver Spring). 2015 Jul;23(7):1493-501. doi: 10.1002/oby.21111.

15.

Epigenetic associations of type 2 diabetes and BMI in an Arab population.

Al Muftah WA, Al-Shafai M, Zaghlool SB, Visconti A, Tsai PC, Kumar P, Spector T, Bell J, Falchi M, Suhre K.

Clin Epigenetics. 2016 Jan 28;8:13. doi: 10.1186/s13148-016-0177-6. eCollection 2016.

16.

Methylation of SOCS3 is inversely associated with metabolic syndrome in an epigenome-wide association study of obesity.

Ali O, Cerjak D, Kent JW Jr, James R, Blangero J, Carless MA, Zhang Y.

Epigenetics. 2016 Sep;11(9):699-707. doi: 10.1080/15592294.2016.1216284. Epub 2016 Aug 26.

17.

DNA Methylation and BMI: Investigating Identified Methylation Sites at HIF3A in a Causal Framework.

Richmond RC, Sharp GC, Ward ME, Fraser A, Lyttleton O, McArdle WL, Ring SM, Gaunt TR, Lawlor DA, Davey Smith G, Relton CL.

Diabetes. 2016 May;65(5):1231-44. doi: 10.2337/db15-0996. Epub 2016 Feb 9.

18.

Association of a Genetic Risk Score With Body Mass Index Across Different Birth Cohorts.

Walter S, Mejía-Guevara I, Estrada K, Liu SY, Glymour MM.

JAMA. 2016 Jul 5;316(1):63-9. doi: 10.1001/jama.2016.8729.

PMID:
27380344
19.

The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes.

Dahlman I, Sinha I, Gao H, Brodin D, Thorell A, Rydén M, Andersson DP, Henriksson J, Perfilyev A, Ling C, Dahlman-Wright K, Arner P.

Int J Obes (Lond). 2015 Jun;39(6):910-9. doi: 10.1038/ijo.2015.31. Epub 2015 Mar 18.

PMID:
25783037
20.

HIF3A association with adiposity: the story begins before birth.

Pan H, Lin X, Wu Y, Chen L, Teh AL, Soh SE, Lee YS, Tint MT, MacIsaac JL, Morin AM, Tan KH, Yap F, Saw SM, Kobor MS, Meaney MJ, Godfrey KM, Chong YS, Gluckman PD, Karnani N, Holbrook JD; GUSTO Study Group.

Epigenomics. 2015;7(6):937-50. doi: 10.2217/epi.15.45. Epub 2015 May 26.

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