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Items: 1 to 20 of 101

1.

HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress.

Zhang L, Chen X, Sharma P, Moon M, Sheftel AD, Dawood F, Nghiem MP, Wu J, Li RK, Gramolini AO, Sorensen PH, Penninger JM, Brumell JH, Liu PP.

Nat Commun. 2014 Mar 11;5:3430. doi: 10.1038/ncomms4430.

2.

Ubiquitylation of autophagy receptor Optineurin by HACE1 activates selective autophagy for tumor suppression.

Liu Z, Chen P, Gao H, Gu Y, Yang J, Peng H, Xu X, Wang H, Yang M, Liu X, Fan L, Chen S, Zhou J, Sun Y, Ruan K, Cheng S, Komatsu M, White E, Li L, Ji H, Finley D, Hu R.

Cancer Cell. 2014 Jul 14;26(1):106-20. doi: 10.1016/j.ccr.2014.05.015.

3.

Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradation.

Fujita K, Maeda D, Xiao Q, Srinivasula SM.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1427-32. doi: 10.1073/pnas.1014156108. Epub 2011 Jan 10.

4.

Inclusion bodies enriched for p62 and polyubiquitinated proteins in macrophages protect against atherosclerosis.

Sergin I, Bhattacharya S, Emanuel R, Esen E, Stokes CJ, Evans TD, Arif B, Curci JA, Razani B.

Sci Signal. 2016 Jan 5;9(409):ra2. doi: 10.1126/scisignal.aad5614.

5.

Pressure Overload-Induced Cardiac Dysfunction in Aged Male Adiponectin Knockout Mice Is Associated With Autophagy Deficiency.

Jahng JW, Turdi S, Kovacevic V, Dadson K, Li RK, Sweeney G.

Endocrinology. 2015 Jul;156(7):2667-77. doi: 10.1210/en.2015-1162. Epub 2015 May 11.

PMID:
25961840
6.

Preconditioning involves selective mitophagy mediated by Parkin and p62/SQSTM1.

Huang C, Andres AM, Ratliff EP, Hernandez G, Lee P, Gottlieb RA.

PLoS One. 2011;6(6):e20975. doi: 10.1371/journal.pone.0020975. Epub 2011 Jun 8.

7.

TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis.

Pan JA, Sun Y, Jiang YP, Bott AJ, Jaber N, Dou Z, Yang B, Chen JS, Catanzaro JM, Du C, Ding WX, Diaz-Meco MT, Moscat J, Ozato K, Lin RZ, Zong WX.

Mol Cell. 2016 Mar 3;61(5):720-733. doi: 10.1016/j.molcel.2016.02.007. Erratum in: Mol Cell. 2016 Apr 7;62(1):149-51.

8.

Accumulation of p62 in degenerated spinal cord under chronic mechanical compression: functional analysis of p62 and autophagy in hypoxic neuronal cells.

Tanabe F, Yone K, Kawabata N, Sakakima H, Matsuda F, Ishidou Y, Maeda S, Abematsu M, Komiya S, Setoguchi T.

Autophagy. 2011 Dec;7(12):1462-71.

9.

The tumour suppressor HACE1 controls cell migration by regulating Rac1 degradation.

Castillo-Lluva S, Tan CT, Daugaard M, Sorensen PH, Malliri A.

Oncogene. 2013 Mar 28;32(13):1735-42. doi: 10.1038/onc.2012.189. Epub 2012 May 21.

PMID:
22614015
10.

Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding.

Cha-Molstad H, Sung KS, Hwang J, Kim KA, Yu JE, Yoo YD, Jang JM, Han DH, Molstad M, Kim JG, Lee YJ, Zakrzewska A, Kim SH, Kim ST, Kim SY, Lee HG, Soung NK, Ahn JS, Ciechanover A, Kim BY, Kwon YT.

Nat Cell Biol. 2015 Jul;17(7):917-29. doi: 10.1038/ncb3177. Epub 2015 Jun 15.

11.

LC3- and p62-based biochemical methods for the analysis of autophagy progression in mammalian cells.

Jiang P, Mizushima N.

Methods. 2015 Mar;75:13-8. doi: 10.1016/j.ymeth.2014.11.021. Epub 2014 Dec 5.

PMID:
25484342
12.

Tumor necrosis factor alpha stimulates p62 accumulation and enhances proteasome activity independently of ROS.

Opperman CM, Sishi BJ.

Cell Biol Toxicol. 2015 Apr;31(2):83-94. doi: 10.1007/s10565-015-9295-8. Epub 2015 Mar 12.

PMID:
25761618
13.

Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism.

Gal J, Ström AL, Kwinter DM, Kilty R, Zhang J, Shi P, Fu W, Wooten MW, Zhu H.

J Neurochem. 2009 Nov;111(4):1062-73. doi: 10.1111/j.1471-4159.2009.06388.x. Epub 2009 Sep 18.

14.

Loss of the tumor suppressor Hace1 leads to ROS-dependent glutamine addiction.

Cetinbas N, Daugaard M, Mullen AR, Hajee S, Rotblat B, Lopez A, Li A, DeBerardinis RJ, Sorensen PH.

Oncogene. 2015 Jul 23;34(30):4005-10. doi: 10.1038/onc.2014.316. Epub 2014 Oct 6.

15.

COP9 signalosome controls the degradation of cytosolic misfolded proteins and protects against cardiac proteotoxicity.

Su H, Li J, Zhang H, Ma W, Wei N, Liu J, Wang X.

Circ Res. 2015 Nov 6;117(11):956-66. doi: 10.1161/CIRCRESAHA.115.306783. Epub 2015 Sep 17.

16.

Developmental regulation of MURF ubiquitin ligases and autophagy proteins nbr1, p62/SQSTM1 and LC3 during cardiac myofibril assembly and turnover.

Perera S, Holt MR, Mankoo BS, Gautel M.

Dev Biol. 2011 Mar 1;351(1):46-61. doi: 10.1016/j.ydbio.2010.12.024. Epub 2010 Dec 23.

17.

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.

Komatsu M, Waguri S, Koike M, Sou YS, Ueno T, Hara T, Mizushima N, Iwata J, Ezaki J, Murata S, Hamazaki J, Nishito Y, Iemura S, Natsume T, Yanagawa T, Uwayama J, Warabi E, Yoshida H, Ishii T, Kobayashi A, Yamamoto M, Yue Z, Uchiyama Y, Kominami E, Tanaka K.

Cell. 2007 Dec 14;131(6):1149-63.

18.

Tumorigenesis in tuberous sclerosis complex is autophagy and p62/sequestosome 1 (SQSTM1)-dependent.

Parkhitko A, Myachina F, Morrison TA, Hindi KM, Auricchio N, Karbowniczek M, Wu JJ, Finkel T, Kwiatkowski DJ, Yu JJ, Henske EP.

Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12455-60. doi: 10.1073/pnas.1104361108. Epub 2011 Jul 11.

19.

Nuclear AMPK regulated CARM1 stabilization impacts autophagy in aged heart.

Li C, Yu L, Xue H, Yang Z, Yin Y, Zhang B, Chen M, Ma H.

Biochem Biophys Res Commun. 2017 Apr 29;486(2):398-405. doi: 10.1016/j.bbrc.2017.03.053. Epub 2017 Mar 15.

PMID:
28315332
20.

Role of autophagy, SQSTM1, SH3GLB1, and TRIM63 in the turnover of nicotinic acetylcholine receptors.

Khan MM, Strack S, Wild F, Hanashima A, Gasch A, Brohm K, Reischl M, Carnio S, Labeit D, Sandri M, Labeit S, Rudolf R.

Autophagy. 2014 Jan;10(1):123-36. doi: 10.4161/auto.26841. Epub 2013 Nov 8.

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