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Items: 1 to 20 of 105

1.

Synthesis and in vitro evaluation of 12-(substituted aminomethyl) berberrubine derivatives as anti-diabetics.

Li R, Wu J, He Y, Hai L, Wu Y.

Bioorg Med Chem Lett. 2014 Apr 1;24(7):1762-5. doi: 10.1016/j.bmcl.2014.02.032. Epub 2014 Feb 21.

PMID:
24613165
2.

Synthesis of 13-(substituted benzyl) berberine and berberrubine derivatives as antifungal agents.

Park KD, Lee JH, Kim SH, Kang TH, Moon JS, Kim SU.

Bioorg Med Chem Lett. 2006 Aug 1;16(15):3913-6. Epub 2006 May 30.

PMID:
16730982
3.

[8-hydroxy-dihydroberberine ameliorated insulin resistance induced by high FFA and high glucose in 3T3-L1 adipocytes].

Xu LJ, Lu FE, Yi P, Wang ZS, Wei SC, Chen G, Dong H, Zou X.

Yao Xue Xue Bao. 2009 Nov;44(11):1304-8. Chinese.

PMID:
21355331
4.

Berberine regulates peroxisome proliferator-activated receptors and positive transcription elongation factor b expression in diabetic adipocytes.

Zhou J, Zhou S.

Eur J Pharmacol. 2010 Dec 15;649(1-3):390-7. doi: 10.1016/j.ejphar.2010.09.030. Epub 2010 Sep 21.

PMID:
20868663
5.

Synthesis of chalcone derivatives as potential anti-diabetic agents.

Hsieh CT, Hsieh TJ, El-Shazly M, Chuang DW, Tsai YH, Yen CT, Wu SF, Wu YC, Chang FR.

Bioorg Med Chem Lett. 2012 Jun 15;22(12):3912-5. doi: 10.1016/j.bmcl.2012.04.108. Epub 2012 Apr 30.

PMID:
22608392
6.

[Synthesis and biological activity of a series of benzopyran derivatives].

Tang L, Yang YS, Ji RY.

Yao Xue Xue Bao. 2008 Feb;43(2):162-8. Chinese.

PMID:
18507343
7.

Thiazolidin-4-one and thiazinan-4-one derivatives analogous to rosiglitazone as potential antihyperglycemic and antidyslipidemic agents.

Raza S, Srivastava SP, Srivastava DS, Srivastava AK, Haq W, Katti SB.

Eur J Med Chem. 2013 May;63:611-20. doi: 10.1016/j.ejmech.2013.01.054. Epub 2013 Feb 9.

PMID:
23567949
8.

Poliothrysoside and its derivatives as novel insulin sensitizers potentially driving AMPK activation and inhibiting adipogenesis.

Sashidhara KV, Singh SP, Varshney S, Beg M, Gaikwad AN.

Eur J Med Chem. 2014 Oct 30;86:570-7. doi: 10.1016/j.ejmech.2014.09.015. Epub 2014 Sep 6.

PMID:
25216379
9.

Molecular design, synthesis, and hypoglycemic activity of a series of thiazolidine-2,4-diones.

Oguchi M, Wada K, Honma H, Tanaka A, Kaneko T, Sakakibara S, Ohsumi J, Serizawa N, Fujiwara T, Horikoshi H, Fujita T.

J Med Chem. 2000 Aug 10;43(16):3052-66.

PMID:
10956213
10.

Evaluation of the antidiabetic potential of selected medicinal plant extracts from the Canadian boreal forest used to treat symptoms of diabetes: part II.

Harbilas D, Martineau LC, Harris CS, Adeyiwola-Spoor DC, Saleem A, Lambert J, Caves D, Johns T, Prentki M, Cuerrier A, Arnason JT, Bennett SA, Haddad PS.

Can J Physiol Pharmacol. 2009 Jun;87(6):479-92. doi: 10.1139/y09-029.

PMID:
19526043
11.

Synthesis of 9-substituted derivatives of berberine as anti-HIV agents.

Bodiwala HS, Sabde S, Mitra D, Bhutani KK, Singh IP.

Eur J Med Chem. 2011 Apr;46(4):1045-9. doi: 10.1016/j.ejmech.2011.01.016. Epub 2011 Jan 21.

PMID:
21295891
12.

Gly-Ala-Gly-Val-Gly-Tyr, a novel synthetic peptide, improves glucose transport and exerts beneficial lipid metabolic effects in 3T3-L1 adipoctyes.

Kim ED, Kim E, Lee JH, Hyun CK.

Eur J Pharmacol. 2011 Jan 10;650(1):479-85. doi: 10.1016/j.ejphar.2010.10.006. Epub 2010 Oct 14.

PMID:
20951125
13.

Design and synthesis of novel imidazoline derivatives with potent antihyperglycemic activity in a rat model of type 2 diabetes.

Crane L, Anastassiadou M, El Hage S, Stigliani JL, Baziard-Mouysset G, Payard M, Leger JM, Bizot-Espiard JG, Ktorza A, Caignard DH, Renard P.

Bioorg Med Chem. 2006 Nov 15;14(22):7419-33. Epub 2006 Aug 2.

PMID:
16889967
14.

[Synthesis of phenyloxyisobutyric acid derivatives and their antidiabetic activity in vitro].

Zeng QL, Wang HQ, Luo H, Gao XP, Liu ZR, Li BG, Wang FP, Zhao YF.

Yao Xue Xue Bao. 2006 Feb;41(2):108-14. Chinese.

PMID:
16671538
15.

Synthesis and antihyperglycemic evaluation of various protoberberine derivatives.

Bian X, He L, Yang G.

Bioorg Med Chem Lett. 2006 Mar 1;16(5):1380-3. Epub 2005 Dec 15.

PMID:
16359864
16.

Rosiglitazone increases cell surface GLUT4 levels in 3T3-L1 adipocytes through an enhancement of endosomal recycling.

Martinez L, Berenguer M, Bruce MC, Le Marchand-Brustel Y, Govers R.

Biochem Pharmacol. 2010 May 1;79(9):1300-9. doi: 10.1016/j.bcp.2009.12.013. Epub 2009 Dec 21.

PMID:
20026082
17.

Synthesis and antifungal activity of a novel series of 13-(4-isopropylbenzyl)berberine derivatives.

Park KD, Cho SJ, Moon JS, Kim SU.

Bioorg Med Chem Lett. 2010 Nov 15;20(22):6551-4. doi: 10.1016/j.bmcl.2010.09.045. Epub 2010 Sep 21.

PMID:
20932752
18.

Antimicrobial activity of 9-O-acyl- and 9-O-benzoyl-substituted berberrubines.

Hong SW, Kim SH, Jeun JA, Lee SJ, Kim SU, Kim JH.

Planta Med. 2000 May;66(4):361-3.

PMID:
10865456
19.

[Design, synthesis and insulin-sensitizing activity of indole derivatives].

Tang L, Yang YS, Ji RY.

Yao Xue Xue Bao. 2006 Mar;41(3):225-9. Chinese.

PMID:
16758992
20.

Design and synthesis of imidazoline derivatives active on glucose homeostasis in a rat model of type II diabetes. 2. Syntheses and biological activities of 1,4-dialkyl-, 1,4-dibenzyl, and 1-benzyl-4-alkyl-2-(4',5'-dihydro-1'H-imidazol-2'-yl)piperazines and isosteric analogues of imidazoline.

Le Bihan G, Rondu F, Pelé-Tounian A, Wang X, Lidy S, Touboul E, Lamouri A, Dive G, Huet J, Pfeiffer B, Renard P, Guardiola-Lemaître B, Manéchez D, Pénicaud L, Ktorza A, Godfroid JJ.

J Med Chem. 1999 May 6;42(9):1587-603.

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