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Items: 1 to 20 of 147

1.

Flotillins bind to the dileucine sorting motif of β-site amyloid precursor protein-cleaving enzyme 1 and influence its endosomal sorting.

John BA, Meister M, Banning A, Tikkanen R.

FEBS J. 2014 Apr;281(8):2074-87. doi: 10.1111/febs.12763. Epub 2014 Mar 6.

2.

ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1.

Sannerud R, Declerck I, Peric A, Raemaekers T, Menendez G, Zhou L, Veerle B, Coen K, Munck S, De Strooper B, Schiavo G, Annaert W.

Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):E559-68. doi: 10.1073/pnas.1100745108. Epub 2011 Aug 8.

3.

GGA proteins regulate retrograde transport of BACE1 from endosomes to the trans-Golgi network.

Wahle T, Prager K, Raffler N, Haass C, Famulok M, Walter J.

Mol Cell Neurosci. 2005 Jul;29(3):453-61.

PMID:
15886016
4.

Β-site APP-cleaving enzyme 1 trafficking and Alzheimer's disease pathogenesis.

Tan J, Evin G.

J Neurochem. 2012 Mar;120(6):869-80. doi: 10.1111/j.1471-4159.2011.07623.x. Epub 2012 Jan 23. Review.

5.

The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1).

von Einem B, Wahler A, Schips T, Serrano-Pozo A, Proepper C, Boeckers TM, Rueck A, Wirth T, Hyman BT, Danzer KM, Thal DR, von Arnim CA.

PLoS One. 2015 Jun 8;10(6):e0129047. doi: 10.1371/journal.pone.0129047. eCollection 2015.

6.

Adaptor protein 2-mediated endocytosis of the β-secretase BACE1 is dispensable for amyloid precursor protein processing.

Prabhu Y, Burgos PV, Schindler C, Farías GG, Magadán JG, Bonifacino JS.

Mol Biol Cell. 2012 Jun;23(12):2339-51. doi: 10.1091/mbc.E11-11-0944. Epub 2012 May 2. Erratum in: Mol Biol Cell. 2012 Jul;23(13):2620.

7.

Intracellular itinerary of internalised β-secretase, BACE1, and its potential impact on β-amyloid peptide biogenesis.

Chia PZ, Toh WH, Sharples R, Gasnereau I, Hill AF, Gleeson PA.

Traffic. 2013 Sep;14(9):997-1013. doi: 10.1111/tra.12088. Epub 2013 Jul 8.

8.

BACE1 protein endocytosis and trafficking are differentially regulated by ubiquitination at lysine 501 and the Di-leucine motif in the carboxyl terminus.

Kang EL, Biscaro B, Piazza F, Tesco G.

J Biol Chem. 2012 Dec 14;287(51):42867-80. doi: 10.1074/jbc.M112.407072. Epub 2012 Oct 29.

9.

BACE1 retrograde trafficking is uniquely regulated by the cytoplasmic domain of sortilin.

Finan GM, Okada H, Kim TW.

J Biol Chem. 2011 Apr 8;286(14):12602-16. doi: 10.1074/jbc.M110.170217. Epub 2011 Jan 18.

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12.

Identification of phospholipid scramblase 1 as a novel interacting molecule with beta -secretase (beta -site amyloid precursor protein (APP) cleaving enzyme (BACE)).

Kametaka S, Shibata M, Moroe K, Kanamori S, Ohsawa Y, Waguri S, Sims PJ, Emoto K, Umeda M, Uchiyama Y.

J Biol Chem. 2003 Apr 25;278(17):15239-45. Epub 2003 Feb 13.

13.

Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.

Deng Y, Wang Z, Wang R, Zhang X, Zhang S, Wu Y, Staufenbiel M, Cai F, Song W.

Eur J Neurosci. 2013 Jun;37(12):1962-9. doi: 10.1111/ejn.12235.

PMID:
23773065
14.

Retromers in Alzheimer's disease.

Siegenthaler BM, Rajendran L.

Neurodegener Dis. 2012;10(1-4):116-21. doi: 10.1159/000335910. Epub 2012 Mar 3. Review.

PMID:
22398391
15.

GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production.

Herskowitz JH, Offe K, Deshpande A, Kahn RA, Levey AI, Lah JJ.

Mol Biol Cell. 2012 Jul;23(14):2645-57. doi: 10.1091/mbc.E12-01-0014. Epub 2012 May 23.

16.

Ubiquitin regulates GGA3-mediated degradation of BACE1.

Kang EL, Cameron AN, Piazza F, Walker KR, Tesco G.

J Biol Chem. 2010 Jul 30;285(31):24108-19. doi: 10.1074/jbc.M109.092742. Epub 2010 May 18.

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GGA proteins mediate the recycling pathway of memapsin 2 (BACE).

He X, Li F, Chang WP, Tang J.

J Biol Chem. 2005 Mar 25;280(12):11696-703. Epub 2004 Dec 21.

20.

Insights into the phosphoregulation of beta-secretase sorting signal by the VHS domain of GGA1.

Shiba T, Kametaka S, Kawasaki M, Shibata M, Waguri S, Uchiyama Y, Wakatsuki S.

Traffic. 2004 Jun;5(6):437-48.

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