Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 173

1.

Acute metformin preconditioning confers neuroprotection against focal cerebral ischaemia by pre-activation of AMPK-dependent autophagy.

Jiang T, Yu JT, Zhu XC, Wang HF, Tan MS, Cao L, Zhang QQ, Gao L, Shi JQ, Zhang YD, Tan L.

Br J Pharmacol. 2014 Jul;171(13):3146-57. doi: 10.1111/bph.12655.

2.

Ischemic preconditioning provides neuroprotection by induction of AMP-activated protein kinase-dependent autophagy in a rat model of ischemic stroke.

Jiang T, Yu JT, Zhu XC, Zhang QQ, Tan MS, Cao L, Wang HF, Shi JQ, Gao L, Qin H, Zhang YD, Tan L.

Mol Neurobiol. 2015 Feb;51(1):220-9. doi: 10.1007/s12035-014-8725-6. Epub 2014 May 10.

PMID:
24809692
3.
4.

Chronic Metformin Preconditioning Provides Neuroprotection via Suppression of NF-κB-Mediated Inflammatory Pathway in Rats with Permanent Cerebral Ischemia.

Zhu XC, Jiang T, Zhang QQ, Cao L, Tan MS, Wang HF, Ding ZZ, Tan L, Yu JT.

Mol Neurobiol. 2015 Aug;52(1):375-85. doi: 10.1007/s12035-014-8866-7. Epub 2014 Aug 30.

PMID:
25172433
5.

Autophagy activation is involved in neuroprotection induced by hyperbaric oxygen preconditioning against focal cerebral ischemia in rats.

Yan W, Zhang H, Bai X, Lu Y, Dong H, Xiong L.

Brain Res. 2011 Jul 21;1402:109-21. doi: 10.1016/j.brainres.2011.05.049. Epub 2011 May 27.

PMID:
21684529
6.

Pre-stroke Metformin Treatment is Neuroprotective Involving AMPK Reduction.

Deng T, Zheng YR, Hou WW, Yuan Y, Shen Z, Wu XL, Chen Y, Zhang LS, Hu WW, Chen Z, Zhang XN.

Neurochem Res. 2016 Oct;41(10):2719-2727. Epub 2016 Jun 27.

PMID:
27350579
7.

Activation of AMP-activated protein kinase by metformin protects against global cerebral ischemia in male rats: interference of AMPK/PGC-1α pathway.

Ashabi G, Khodagholi F, Khalaj L, Goudarzvand M, Nasiri M.

Metab Brain Dis. 2014 Mar;29(1):47-58. doi: 10.1007/s11011-013-9475-2. Epub 2014 Jan 18.

PMID:
24435937
8.

Autophagy activation is associated with neuroprotection in a rat model of focal cerebral ischemic preconditioning.

Sheng R, Zhang LS, Han R, Liu XQ, Gao B, Qin ZH.

Autophagy. 2010 May;6(4):482-94. doi: 10.4161/auto.6.4.11737. Epub 2010 May 16.

PMID:
20400854
9.

Metformin pretreatment enhanced learning and memory in cerebral forebrain ischaemia: the role of the AMPK/BDNF/P70SK signalling pathway.

Ghadernezhad N, Khalaj L, Pazoki-Toroudi H, Mirmasoumi M, Ashabi G.

Pharm Biol. 2016 Oct;54(10):2211-9. doi: 10.3109/13880209.2016.1150306. Epub 2016 Mar 9.

PMID:
26960058
10.

Autophagy activation contributes to the neuroprotection of remote ischemic perconditioning against focal cerebral ischemia in rats.

Su J, Zhang T, Wang K, Zhu T, Li X.

Neurochem Res. 2014 Nov;39(11):2068-77. doi: 10.1007/s11064-014-1396-x. Epub 2014 Aug 1.

PMID:
25082119
11.

Inhibition of autophagy contributes to ischemic postconditioning-induced neuroprotection against focal cerebral ischemia in rats.

Gao L, Jiang T, Guo J, Liu Y, Cui G, Gu L, Su L, Zhang Y.

PLoS One. 2012;7(9):e46092. doi: 10.1371/journal.pone.0046092. Epub 2012 Sep 28.

12.

The endoplasmic reticulum stress inhibitor salubrinal inhibits the activation of autophagy and neuroprotection induced by brain ischemic preconditioning.

Gao B, Zhang XY, Han R, Zhang TT, Chen C, Qin ZH, Sheng R.

Acta Pharmacol Sin. 2013 May;34(5):657-66. doi: 10.1038/aps.2013.34. Epub 2013 Apr 22.

13.

[Effectiveness of metformin in prevention of development of hyperglycemia and neuronal damage caused by ischemic stress].

Fujita-Hamabe W, Harada S, Tokuyama S.

Yakugaku Zasshi. 2011 Apr;131(4):533-8. Review. Japanese.

14.

Effects of metformin in experimental stroke.

Li J, Benashski SE, Venna VR, McCullough LD.

Stroke. 2010 Nov;41(11):2645-52. doi: 10.1161/STROKEAHA.110.589697. Epub 2010 Sep 16.

15.

Inhibition of AMP-activated protein kinase alleviates focal cerebral ischemia injury in mice: Interference with mTOR and autophagy.

Fu L, Huang L, Cao C, Yin Q, Liu J.

Brain Res. 2016 Nov 1;1650:103-111. doi: 10.1016/j.brainres.2016.08.035. Epub 2016 Aug 26.

PMID:
27569585
16.

Effect of the AMP-kinase modulators AICAR, metformin and compound C on insulin secretion of INS-1E rat insulinoma cells under standard cell culture conditions.

Langelueddecke C, Jakab M, Ketterl N, Lehner L, Hufnagl C, Schmidt S, Geibel JP, Fuerst J, Ritter M.

Cell Physiol Biochem. 2012;29(1-2):75-86. doi: 10.1159/000337589. Epub 2012 Mar 1.

17.

Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia.

Wang P, Guan YF, Du H, Zhai QW, Su DF, Miao CY.

Autophagy. 2012 Jan;8(1):77-87. doi: 10.4161/auto.8.1.18274. Epub 2012 Jan 1.

PMID:
22113203
18.

Metformin improves anxiety-like behaviors through AMPK-dependent regulation of autophagy following transient forebrain ischemia.

Sarkaki A, Farbood Y, Badavi M, Khalaj L, Khodagholi F, Ashabi G.

Metab Brain Dis. 2015 Oct;30(5):1139-50. doi: 10.1007/s11011-015-9677-x. Epub 2015 May 5.

PMID:
25936719
19.

Metabolic actions of metformin in the heart can occur by AMPK-independent mechanisms.

Saeedi R, Parsons HL, Wambolt RB, Paulson K, Sharma V, Dyck JR, Brownsey RW, Allard MF.

Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2497-506. doi: 10.1152/ajpheart.00873.2007. Epub 2008 Mar 28.

20.

Metformin induces cardioprotection against ischaemia/reperfusion injury in the rat heart 24 hours after administration.

Solskov L, Løfgren B, Kristiansen SB, Jessen N, Pold R, Nielsen TT, Bøtker HE, Schmitz O, Lund S.

Basic Clin Pharmacol Toxicol. 2008 Jul;103(1):82-7. doi: 10.1111/j.1742-7843.2008.00234.x. Epub 2008 Jul 1.

Supplemental Content

Support Center