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Items: 1 to 20 of 263

1.

Comparative genomic analysis of primary and synchronous metastatic colorectal cancers.

Lee SY, Haq F, Kim D, Jun C, Jo HJ, Ahn SM, Lee WS.

PLoS One. 2014 Mar 5;9(3):e90459. doi: 10.1371/journal.pone.0090459. eCollection 2014. Erratum in: PLoS One. 2015;10(1):e0117753.

2.

Subclonal Genomic Architectures of Primary and Metastatic Colorectal Cancer Based on Intratumoral Genetic Heterogeneity.

Kim TM, Jung SH, An CH, Lee SH, Baek IP, Kim MS, Park SW, Rhee JK, Lee SH, Chung YJ.

Clin Cancer Res. 2015 Oct 1;21(19):4461-72. doi: 10.1158/1078-0432.CCR-14-2413. Epub 2015 May 15.

3.

Comparative analysis of primary tumour and matched metastases in colorectal cancer patients: evaluation of concordance between genomic and transcriptional profiles.

Vignot S, Lefebvre C, Frampton GM, Meurice G, Yelensky R, Palmer G, Capron F, Lazar V, Hannoun L, Miller VA, André F, Stephens PJ, Soria JC, Spano JP.

Eur J Cancer. 2015 May;51(7):791-9. doi: 10.1016/j.ejca.2015.02.012. Epub 2015 Mar 18.

PMID:
25797355
4.

Association of p53 mutations, microvessel density and neoangiogenesis in pairs of colorectal cancers and corresponding liver metastases.

Kern A, Taubert H, Scheele J, Rudroff C, Mothes H, Kappler M, Bartel F, Richter KK.

Int J Oncol. 2002 Aug;21(2):243-9.

PMID:
12118317
5.

Clonal origins and parallel evolution of regionally synchronous colorectal adenoma and carcinoma.

Kim TM, An CH, Rhee JK, Jung SH, Lee SH, Baek IP, Kim MS, Lee SH, Chung YJ.

Oncotarget. 2015 Sep 29;6(29):27725-35. doi: 10.18632/oncotarget.4834.

6.

Distinctive Spatiotemporal Stability of Somatic Mutations in Metastasized Microsatellite-stable Colorectal Cancer.

Jesinghaus M, Wolf T, Pfarr N, Muckenhuber A, Ahadova A, Warth A, Goeppert B, Sers C, Kloor M, Endris V, Stenzinger A, Weichert W.

Am J Surg Pathol. 2015 Aug;39(8):1140-7. doi: 10.1097/PAS.0000000000000423.

PMID:
25786087
7.

Comparative genomic analysis of primary versus metastatic colorectal carcinomas.

Vakiani E, Janakiraman M, Shen R, Sinha R, Zeng Z, Shia J, Cercek A, Kemeny N, D'Angelica M, Viale A, Heguy A, Paty P, Chan TA, Saltz LB, Weiser M, Solit DB.

J Clin Oncol. 2012 Aug 20;30(24):2956-62. doi: 10.1200/JCO.2011.38.2994. Epub 2012 Jun 4.

8.

Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level.

Macartney-Coxson DP, Hood KA, Shi HJ, Ward T, Wiles A, O'Connor R, Hall DA, Lea RA, Royds JA, Stubbs RS, Rooker S.

BMC Cancer. 2008 Jul 1;8:187. doi: 10.1186/1471-2407-8-187.

9.

P53 mutations in primary tumors and subsequent liver metastases are related to survival in patients with colorectal carcinoma who undergo liver resection.

Yang Y, Forslund A, Remotti H, Lönnroth C, Andersson M, Brevinge H, Svanberg E, Lindnér P, Hafström L, Naredi P, Lundholm K.

Cancer. 2001 Feb 15;91(4):727-36.

PMID:
11241240
10.

There is no increase in frequency of somatic mutations in metastases compared with primary colorectal carcinomas with microsatellite instability.

Barnetson R, Eckstein R, Robinson B, Schnitzler M.

Genes Chromosomes Cancer. 2003 Oct;38(2):149-56.

PMID:
12939742
11.

Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer.

Kloosterman WP, Hoogstraat M, Paling O, Tavakoli-Yaraki M, Renkens I, Vermaat JS, van Roosmalen MJ, van Lieshout S, Nijman IJ, Roessingh W, van 't Slot R, van de Belt J, Guryev V, Koudijs M, Voest E, Cuppen E.

Genome Biol. 2011 Oct 19;12(10):R103. doi: 10.1186/gb-2011-12-10-r103.

12.

Unique genetic profile of sporadic colorectal cancer liver metastasis versus primary tumors as defined by high-density single-nucleotide polymorphism arrays.

Muñoz-Bellvis L, Fontanillo C, González-González M, Garcia E, Iglesias M, Esteban C, Gutierrez ML, Abad MM, Bengoechea O, De Las Rivas J, Orfao A, Sayagués JM.

Mod Pathol. 2012 Apr;25(4):590-601. doi: 10.1038/modpathol.2011.195. Epub 2012 Jan 6.

13.

Patterns of somatic alterations between matched primary and metastatic colorectal tumors characterized by whole-genome sequencing.

Xie T, Cho YB, Wang K, Huang D, Hong HK, Choi YL, Ko YH, Nam DH, Jin J, Yang H, Fernandez J, Deng S, Rejto PA, Lee WY, Mao M.

Genomics. 2014 Oct;104(4):234-41. doi: 10.1016/j.ygeno.2014.07.012. Epub 2014 Jul 25.

PMID:
25066378
14.

KRAS, NRAS, PIK3CA exon 20, and BRAF genotypes in synchronous and metachronous primary colorectal cancers diagnostic and therapeutic implications.

Balschun K, Haag J, Wenke AK, von Schönfels W, Schwarz NT, Röcken C.

J Mol Diagn. 2011 Jul;13(4):436-45. doi: 10.1016/j.jmoldx.2011.03.002. Epub 2011 May 4.

15.

P53 mutation analysis of colorectal liver metastases: relation to actual survival, angiogenic status, and p53 overexpression.

de Jong KP, Gouw AS, Peeters PM, Bulthuis M, Menkema L, Porte RJ, Slooff MJ, van Goor H, van den Berg A.

Clin Cancer Res. 2005 Jun 1;11(11):4067-73.

16.

Comparative genomic hybridization analysis of primary colorectal carcinomas and their synchronous metastases.

Al-Mulla F, Keith WN, Pickford IR, Going JJ, Birnie GD.

Genes Chromosomes Cancer. 1999 Apr;24(4):306-14.

PMID:
10092128
17.

The status of p53 in the metastatic progression of colorectal cancer.

Heide I, Thiede C, Sonntag T, de Kant E, Neubauer A, Jonas S, Peter FJ, Neuhaus P, Herrmann R, Huhn D, Rochlitz CF.

Eur J Cancer. 1997 Jul;33(8):1314-22.

PMID:
9301461
18.

Prevalence and heterogeneity of KRAS, BRAF, and PIK3CA mutations in primary colorectal adenocarcinomas and their corresponding metastases.

Baldus SE, Schaefer KL, Engers R, Hartleb D, Stoecklein NH, Gabbert HE.

Clin Cancer Res. 2010 Feb 1;16(3):790-9. doi: 10.1158/1078-0432.CCR-09-2446. Epub 2010 Jan 26.

19.

Identification of chromosomal aberrations of metastatic potential in colorectal carcinoma.

Yamamoto S, Midorikawa Y, Morikawa T, Nishimura Y, Sakamoto H, Ishikawa S, Akagi K, Aburatani H.

Genes Chromosomes Cancer. 2010 May;49(5):487-96. doi: 10.1002/gcc.20759.

PMID:
20175194
20.

KRAS mutation analysis: a comparison between primary tumours and matched liver metastases in 305 colorectal cancer patients.

Knijn N, Mekenkamp LJ, Klomp M, Vink-Börger ME, Tol J, Teerenstra S, Meijer JW, Tebar M, Riemersma S, van Krieken JH, Punt CJ, Nagtegaal ID.

Br J Cancer. 2011 Mar 15;104(6):1020-6. doi: 10.1038/bjc.2011.26. Epub 2011 Mar 1.

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