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Items: 1 to 20 of 105

1.

A range of Cℇ3-Cℇ4 interdomain angles in IgE Fc accommodate binding to its receptor CD23.

Dhaliwal B, Pang MO, Yuan D, Beavil AJ, Sutton BJ.

Acta Crystallogr F Struct Biol Commun. 2014 Mar;70(Pt 3):305-9. doi: 10.1107/S2053230X14003355.

2.

Crystal structure of IgE bound to its B-cell receptor CD23 reveals a mechanism of reciprocal allosteric inhibition with high affinity receptor FcεRI.

Dhaliwal B, Yuan D, Pang MO, Henry AJ, Cain K, Oxbrow A, Fabiane SM, Beavil AJ, McDonnell JM, Gould HJ, Sutton BJ.

Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12686-91. doi: 10.1073/pnas.1207278109.

3.

Ca2+-dependent structural changes in the B-cell receptor CD23 increase its affinity for human immunoglobulin E.

Yuan D, Keeble AH, Hibbert RG, Fabiane S, Gould HJ, McDonnell JM, Beavil AJ, Sutton BJ, Dhaliwal B.

J Biol Chem. 2013 Jul 26;288(30):21667-77. doi: 10.1074/jbc.M113.480657.

4.

Conformational plasticity at the IgE-binding site of the B-cell receptor CD23.

Dhaliwal B, Pang MO, Yuan D, Yahya N, Fabiane SM, McDonnell JM, Gould HJ, Beavil AJ, Sutton BJ.

Mol Immunol. 2013 Dec;56(4):693-7. doi: 10.1016/j.molimm.2013.07.005.

5.

Structure and dynamics of IgE-receptor interactions: FcεRI and CD23/FcεRII.

Sutton BJ, Davies AM.

Immunol Rev. 2015 Nov;268(1):222-35. doi: 10.1111/imr.12340. Review.

PMID:
26497523
6.
7.

A fluorescent biosensor reveals conformational changes in human immunoglobulin E Fc: implications for mechanisms of receptor binding, inhibition, and allergen recognition.

Hunt J, Keeble AH, Dale RE, Corbett MK, Beavil RL, Levitt J, Swann MJ, Suhling K, Ameer-Beg S, Sutton BJ, Beavil AJ.

J Biol Chem. 2012 May 18;287(21):17459-70. doi: 10.1074/jbc.M111.331967.

8.

Participation of the N-terminal region of Cepsilon3 in the binding of human IgE to its high-affinity receptor FcepsilonRI.

Henry AJ, Cook JP, McDonnell JM, Mackay GA, Shi J, Sutton BJ, Gould HJ.

Biochemistry. 1997 Dec 16;36(50):15568-78.

PMID:
9398285
9.

Conformational flexibility in immunoglobulin E-Fc 3-4 revealed in multiple crystal forms.

Wurzburg BA, Jardetzky TS.

J Mol Biol. 2009 Oct 16;393(1):176-90. doi: 10.1016/j.jmb.2009.08.012.

10.

Interaction of the low-affinity receptor CD23/Fc epsilonRII lectin domain with the Fc epsilon3-4 fragment of human immunoglobulin E.

Shi J, Ghirlando R, Beavil RL, Beavil AJ, Keown MB, Young RJ, Owens RJ, Sutton BJ, Gould HJ.

Biochemistry. 1997 Feb 25;36(8):2112-22.

PMID:
9047310
11.

Production of a chimeric form of CD23 that is oligomeric and blocks IgE binding to the Fc epsilonRI.

Kelly AE, Chen BH, Woodward EC, Conrad DH.

J Immunol. 1998 Dec 15;161(12):6696-704.

12.

The crystal structure of IgE Fc reveals an asymmetrically bent conformation.

Wan T, Beavil RL, Fabiane SM, Beavil AJ, Sohi MK, Keown M, Young RJ, Henry AJ, Owens RJ, Gould HJ, Sutton BJ.

Nat Immunol. 2002 Jul;3(7):681-6.

PMID:
12068291
13.

Mapping of the CD23 binding site on immunoglobulin E (IgE) and allosteric control of the IgE-Fc epsilonRI interaction.

Borthakur S, Hibbert RG, Pang MO, Yahya N, Bax HJ, Kao MW, Cooper AM, Beavil AJ, Sutton BJ, Gould HJ, McDonnell JM.

J Biol Chem. 2012 Sep 7;287(37):31457-61. doi: 10.1074/jbc.C112.397059.

14.

The oligomeric nature of the murine Fc epsilon RII/CD23. Implications for function.

Dierks SE, Bartlett WC, Edmeades RL, Gould HJ, Rao M, Conrad DH.

J Immunol. 1993 Mar 15;150(6):2372-82.

PMID:
8450218
15.

Structural changes in the lectin domain of CD23, the low-affinity IgE receptor, upon calcium binding.

Wurzburg BA, Tarchevskaya SS, Jardetzky TS.

Structure. 2006 Jun;14(6):1049-58.

16.

Structure of the Fc fragment of human IgE bound to its high-affinity receptor Fc epsilonRI alpha.

Garman SC, Wurzburg BA, Tarchevskaya SS, Kinet JP, Jardetzky TS.

Nature. 2000 Jul 20;406(6793):259-66.

PMID:
10917520
17.

Conformational changes in IgE contribute to its uniquely slow dissociation rate from receptor FcɛRI.

Holdom MD, Davies AM, Nettleship JE, Bagby SC, Dhaliwal B, Girardi E, Hunt J, Gould HJ, Beavil AJ, McDonnell JM, Owens RJ, Sutton BJ.

Nat Struct Mol Biol. 2011 May;18(5):571-6. doi: 10.1038/nsmb.2044.

18.

Identification of contact residues in the IgE binding site of human FcepsilonRIalpha.

Cook JP, Henry AJ, McDonnell JM, Owens RJ, Sutton BJ, Gould HJ.

Biochemistry. 1997 Dec 16;36(50):15579-88.

PMID:
9398286
19.

Structural and Physical Basis for Anti-IgE Therapy.

Wright JD, Chu HM, Huang CH, Ma C, Chang TW, Lim C.

Sci Rep. 2015 Jun 26;5:11581. doi: 10.1038/srep11581.

20.

Thermodynamics of the interaction of human immunoglobulin E with its high-affinity receptor Fc epsilon RI.

Keown MB, Henry AJ, Ghirlando R, Sutton BJ, Gould HJ.

Biochemistry. 1998 Jun 23;37(25):8863-9.

PMID:
9636027
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