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Items: 1 to 20 of 105

1.

Inter-ring rotations of AAA ATPase p97 revealed by electron cryomicroscopy.

Yeung HO, Förster A, Bebeacua C, Niwa H, Ewens C, McKeown C, Zhang X, Freemont PS.

Open Biol. 2014 Mar 5;4:130142. doi: 10.1098/rsob.130142.

2.

Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle.

Rouiller I, DeLaBarre B, May AP, Weis WI, Brunger AT, Milligan RA, Wilson-Kubalek EM.

Nat Struct Biol. 2002 Dec;9(12):950-7.

PMID:
12434150
3.

Nucleotide-dependent conformational changes of the AAA+ ATPase p97 revisited.

Schuller JM, Beck F, Lössl P, Heck AJ, Förster F.

FEBS Lett. 2016 Mar;590(5):595-604. doi: 10.1002/1873-3468.12091. Epub 2016 Feb 20.

4.

Motions and negative cooperativity between p97 domains revealed by cryo-electron microscopy and quantised elastic deformational model.

Beuron F, Flynn TC, Ma J, Kondo H, Zhang X, Freemont PS.

J Mol Biol. 2003 Mar 28;327(3):619-29.

PMID:
12634057
5.

Complete structure of p97/valosin-containing protein reveals communication between nucleotide domains.

DeLaBarre B, Brunger AT.

Nat Struct Biol. 2003 Oct;10(10):856-63. Epub 2003 Aug 31.

PMID:
12949490
6.

Conformational changes in the AAA ATPase p97-p47 adaptor complex.

Beuron F, Dreveny I, Yuan X, Pye VE, McKeown C, Briggs LC, Cliff MJ, Kaneko Y, Wallis R, Isaacson RL, Ladbury JE, Matthews SJ, Kondo H, Zhang X, Freemont PS.

EMBO J. 2006 May 3;25(9):1967-76. Epub 2006 Apr 6.

7.

A major conformational change in p97 AAA ATPase upon ATP binding.

Rouiller I, Butel VM, Latterich M, Milligan RA, Wilson-Kubalek EM.

Mol Cell. 2000 Dec;6(6):1485-90.

8.

2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition.

Banerjee S, Bartesaghi A, Merk A, Rao P, Bulfer SL, Yan Y, Green N, Mroczkowski B, Neitz RJ, Wipf P, Falconieri V, Deshaies RJ, Milne JL, Huryn D, Arkin M, Subramaniam S.

Science. 2016 Feb 19;351(6275):871-5. doi: 10.1126/science.aad7974. Epub 2016 Jan 28.

9.

Structure of the AAA ATPase p97.

Zhang X, Shaw A, Bates PA, Newman RH, Gowen B, Orlova E, Gorman MA, Kondo H, Dokurno P, Lally J, Leonard G, Meyer H, van Heel M, Freemont PS.

Mol Cell. 2000 Dec;6(6):1473-84.

10.
12.

The role of the N-domain in the ATPase activity of the mammalian AAA ATPase p97/VCP.

Niwa H, Ewens CA, Tsang C, Yeung HO, Zhang X, Freemont PS.

J Biol Chem. 2012 Mar 9;287(11):8561-70. doi: 10.1074/jbc.M111.302778. Epub 2012 Jan 23.

13.

Structural insights into the p97-Ufd1-Npl4 complex.

Pye VE, Beuron F, Keetch CA, McKeown C, Robinson CV, Meyer HH, Zhang X, Freemont PS.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):467-72. Epub 2007 Jan 3.

14.

Going through the motions: the ATPase cycle of p97.

Pye VE, Dreveny I, Briggs LC, Sands C, Beuron F, Zhang X, Freemont PS.

J Struct Biol. 2006 Oct;156(1):12-28. Epub 2006 Mar 29.

PMID:
16621604
15.

Interprotomer motion-transmission mechanism for the hexameric AAA ATPase p97.

Li G, Huang C, Zhao G, Lennarz WJ.

Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3737-41. doi: 10.1073/pnas.1200255109. Epub 2012 Feb 21.

16.

p97 Disease Mutations Modulate Nucleotide-Induced Conformation to Alter Protein-Protein Interactions.

Bulfer SL, Chou TF, Arkin MR.

ACS Chem Biol. 2016 Aug 19;11(8):2112-6. doi: 10.1021/acschembio.6b00350. Epub 2016 Jun 13.

17.

A unique IBMPFD-related P97/VCP mutation with differential binding pattern and subcellular localization.

Erzurumlu Y, Kose FA, Gozen O, Gozuacik D, Toth EA, Ballar P.

Int J Biochem Cell Biol. 2013 Apr;45(4):773-82. doi: 10.1016/j.biocel.2013.01.006. Epub 2013 Jan 16.

PMID:
23333620
18.

The AAA+ ATPase p97, a cellular multitool.

Stach L, Freemont PS.

Biochem J. 2017 Aug 17;474(17):2953-2976. doi: 10.1042/BCJ20160783. Review.

19.

Interaction between the AAA+ ATPase p97 and its cofactor ataxin3 in health and disease: Nucleotide-induced conformational changes regulate cofactor binding.

Rao MV, Williams DR, Cocklin S, Loll PJ.

J Biol Chem. 2017 Nov 10;292(45):18392-18407. doi: 10.1074/jbc.M117.806281. Epub 2017 Sep 22.

20.

Altered intersubunit communication is the molecular basis for functional defects of pathogenic p97 mutants.

Tang WK, Xia D.

J Biol Chem. 2013 Dec 20;288(51):36624-35. doi: 10.1074/jbc.M113.488924. Epub 2013 Nov 6.

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