Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 101

1.

Pharmacophore-based screening and identification of novel human ligase I inhibitors with potential anticancer activity.

Krishna S, Singh DK, Meena S, Datta D, Siddiqi MI, Banerjee D.

J Chem Inf Model. 2014 Mar 24;54(3):781-92. doi: 10.1021/ci5000032. Epub 2014 Mar 13.

PMID:
24593844
2.

Human DNA ligases: a comprehensive new look for cancer therapy.

Singh DK, Krishna S, Chandra S, Shameem M, Deshmukh AL, Banerjee D.

Med Res Rev. 2014 May;34(3):567-95. doi: 10.1002/med.21298. Epub 2013 Aug 19. Review.

PMID:
23959747
3.

Rational design of human DNA ligase inhibitors that target cellular DNA replication and repair.

Chen X, Zhong S, Zhu X, Dziegielewska B, Ellenberger T, Wilson GM, MacKerell AD Jr, Tomkinson AE.

Cancer Res. 2008 May 1;68(9):3169-77. doi: 10.1158/0008-5472.CAN-07-6636.

4.

Identification and characterization of novel ligase I inhibitors.

Pandey M, Kumar S, Goldsmith G, Srivastava M, Elango S, Shameem M, Bannerjee D, Choudhary B, Karki SS, Raghavan SC.

Mol Carcinog. 2017 Feb;56(2):550-566. doi: 10.1002/mc.22516. Epub 2016 Jun 27.

PMID:
27312791
5.

Synthetic modified pyrrolo[1,4] benzodiazepine molecules demonstrate selective anticancer activity by targeting the human ligase 1 enzyme: An in silico and in vitro mechanistic study.

Shameem M, Kumar R, Krishna S, Kumar C, Siddiqi MI, Kundu B, Banerjee D.

Chem Biol Interact. 2015 Jul 25;237:115-24. doi: 10.1016/j.cbi.2015.05.024. Epub 2015 Jun 12.

PMID:
26079053
6.

A high-throughput fluorescence resonance energy transfer-based assay for DNA ligase.

Shapiro AB, Eakin AE, Walkup GK, Rivin O.

J Biomol Screen. 2011 Jun;16(5):486-93. doi: 10.1177/1087057111398295. Epub 2011 Mar 11.

PMID:
21398623
7.

SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV.

Greco GE, Matsumoto Y, Brooks RC, Lu Z, Lieber MR, Tomkinson AE.

DNA Repair (Amst). 2016 Jul;43:18-23. doi: 10.1016/j.dnarep.2016.04.004. Epub 2016 May 7.

8.

Identification of a specific inhibitor for DNA ligase I in human cells.

Yang SW, Becker FF, Chan JY.

Proc Natl Acad Sci U S A. 1992 Mar 15;89(6):2227-31.

9.

Tricyclic dihydrobenzoxazepine and tetracyclic indole derivatives can specifically target bacterial DNA ligases and can distinguish them from human DNA ligase I.

Yadav N, Khanam T, Shukla A, Rai N, Hajela K, Ramachandran R.

Org Biomol Chem. 2015 May 21;13(19):5475-87. doi: 10.1039/c5ob00439j.

PMID:
25875403
10.

NAD(+)-dependent DNA ligase: a novel target waiting for the right inhibitor.

Dwivedi N, Dube D, Pandey J, Singh B, Kukshal V, Ramachandran R, Tripathi RP.

Med Res Rev. 2008 Jul;28(4):545-68. Review.

PMID:
18080330
11.

Mycobacterium tuberculosis NAD+-dependent DNA ligase is selectively inhibited by glycosylamines compared with human DNA ligase I.

Srivastava SK, Dube D, Tewari N, Dwivedi N, Tripathi RP, Ramachandran R.

Nucleic Acids Res. 2005 Dec 15;33(22):7090-101. Print 2005.

12.

Synthesis and bio-evaluation of indole-chalcone based benzopyrans as promising antiligase and antiproliferative agents.

Gupta S, Maurya P, Upadhyay A, Kushwaha P, Krishna S, Siddiqi MI, Sashidhara KV, Banerjee D.

Eur J Med Chem. 2018 Jan 1;143:1981-1996. doi: 10.1016/j.ejmech.2017.11.015. Epub 2017 Nov 7.

PMID:
29146133
13.

Identification and validation of human DNA ligase inhibitors using computer-aided drug design.

Zhong S, Chen X, Zhu X, Dziegielewska B, Bachman KE, Ellenberger T, Ballin JD, Wilson GM, Tomkinson AE, MacKerell AD Jr.

J Med Chem. 2008 Aug 14;51(15):4553-62. doi: 10.1021/jm8001668. Epub 2008 Jul 17.

14.

Enhancement of DNA ligase I level by gemcitabine in human cancer cells.

Sun D, Urrabaz R, Kelly S, Nguyen M, Weitman S.

Clin Cancer Res. 2002 Apr;8(4):1189-95.

15.

Human DNA ligases I, III, and IV-purification and new specific assays for these enzymes.

Chen X, Pascal J, Vijayakumar S, Wilson GM, Ellenberger T, Tomkinson AE.

Methods Enzymol. 2006;409:39-52.

PMID:
16793394
16.

Specific and potent inhibition of NAD+-dependent DNA ligase by pyridochromanones.

Brötz-Oesterhelt H, Knezevic I, Bartel S, Lampe T, Warnecke-Eberz U, Ziegelbauer K, Häbich D, Labischinski H.

J Biol Chem. 2003 Oct 10;278(41):39435-42. Epub 2003 Jul 15.

17.

Targeting abnormal DNA double-strand break repair in tyrosine kinase inhibitor-resistant chronic myeloid leukemias.

Tobin LA, Robert C, Rapoport AP, Gojo I, Baer MR, Tomkinson AE, Rassool FV.

Oncogene. 2013 Apr 4;32(14):1784-93. doi: 10.1038/onc.2012.203. Epub 2012 May 28.

18.

Inhibition of human DNA ligase I activity by zinc and cadmium and the fidelity of ligation.

Yang SW, Becker FF, Chan JY.

Environ Mol Mutagen. 1996;28(1):19-25.

PMID:
8698042
19.
20.

DNA ligase IV as a new molecular target for temozolomide.

Kondo N, Takahashi A, Mori E, Ohnishi K, McKinnon PJ, Sakaki T, Nakase H, Ohnishi T.

Biochem Biophys Res Commun. 2009 Oct 2;387(4):656-60. doi: 10.1016/j.bbrc.2009.07.045. Epub 2009 Jul 15.

Supplemental Content

Support Center