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Items: 1 to 20 of 103

1.

Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models.

Skouta R, Dixon SJ, Wang J, Dunn DE, Orman M, Shimada K, Rosenberg PA, Lo DC, Weinberg JM, Linkermann A, Stockwell BR.

J Am Chem Soc. 2014 Mar 26;136(12):4551-6. doi: 10.1021/ja411006a. Epub 2014 Mar 14.

PMID:
24592866
2.

Novel Ferroptosis Inhibitors with Improved Potency and ADME Properties.

Hofmans S, Vanden Berghe T, Devisscher L, Hassannia B, Lyssens S, Joossens J, Van Der Veken P, Vandenabeele P, Augustyns K.

J Med Chem. 2016 Mar 10;59(5):2041-53. doi: 10.1021/acs.jmedchem.5b01641. Epub 2016 Feb 8.

PMID:
26696014
3.

The neuroprotective role of ferrostatin-1 under rotenone-induced oxidative stress in dopaminergic neuroblastoma cells.

Kabiraj P, Valenzuela CA, Marin JE, Ramirez DA, Mendez L, Hwang MS, Varela-Ramirez A, Fenelon K, Narayan M, Skouta R.

Protein J. 2015 Oct;34(5):349-58. doi: 10.1007/s10930-015-9629-7.

PMID:
26385697
4.

Ferroptosis: an iron-dependent form of nonapoptotic cell death.

Dixon SJ, Lemberg KM, Lamprecht MR, Skouta R, Zaitsev EM, Gleason CE, Patel DN, Bauer AJ, Cantley AM, Yang WS, Morrison B 3rd, Stockwell BR.

Cell. 2012 May 25;149(5):1060-72. doi: 10.1016/j.cell.2012.03.042.

PMID:
22632970
5.

Mechanisms of ferroptosis.

Cao JY, Dixon SJ.

Cell Mol Life Sci. 2016 Jun;73(11-12):2195-209. doi: 10.1007/s00018-016-2194-1. Epub 2016 Apr 5. Review.

PMID:
27048822
6.

Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington's disease mice.

Lee J, Kosaras B, Del Signore SJ, Cormier K, McKee A, Ratan RR, Kowall NW, Ryu H.

Acta Neuropathol. 2011 Apr;121(4):487-98. doi: 10.1007/s00401-010-0788-5. Epub 2010 Dec 16.

PMID:
21161248
7.

Nitrosative and oxidative injury to premyelinating oligodendrocytes in periventricular leukomalacia.

Haynes RL, Folkerth RD, Keefe RJ, Sung I, Swzeda LI, Rosenberg PA, Volpe JJ, Kinney HC.

J Neuropathol Exp Neurol. 2003 May;62(5):441-50.

PMID:
12769184
8.

Probucol modulates oxidative stress and excitotoxicity in Huntington's disease models in vitro.

Colle D, Hartwig JM, Soares FA, Farina M.

Brain Res Bull. 2012 Mar 10;87(4-5):397-405. doi: 10.1016/j.brainresbull.2012.01.003. Epub 2012 Jan 11.

PMID:
22245028
9.

The 5-Lipoxygenase Inhibitor Zileuton Confers Neuroprotection against Glutamate Oxidative Damage by Inhibiting Ferroptosis.

Liu Y, Wang W, Li Y, Xiao Y, Cheng J, Jia J.

Biol Pharm Bull. 2015;38(8):1234-9. doi: 10.1248/bpb.b15-00048.

PMID:
26235588
10.

On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death.

Zilka O, Shah R, Li B, Friedmann Angeli JP, Griesser M, Conrad M, Pratt DA.

ACS Cent Sci. 2017 Mar 22;3(3):232-243. doi: 10.1021/acscentsci.7b00028. Epub 2017 Mar 7.

PMID:
28386601
11.

Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells.

Ooko E, Saeed ME, Kadioglu O, Sarvi S, Colak M, Elmasaoudi K, Janah R, Greten HJ, Efferth T.

Phytomedicine. 2015 Oct 15;22(11):1045-54. doi: 10.1016/j.phymed.2015.08.002. Epub 2015 Aug 18.

PMID:
26407947
12.

Time-Course Analysis of Protein and Lipid Oxidation in the Brains of Yac128 Huntington's Disease Transgenic Mice.

Brocardo PS, McGinnis E, Christie BR, Gil-Mohapel J.

Rejuvenation Res. 2016 Apr;19(2):140-8. doi: 10.1089/rej.2015.1736. Epub 2016 Feb 2.

PMID:
26371883
13.

Inhibitors of metabolism rescue cell death in Huntington's disease models.

Varma H, Cheng R, Voisine C, Hart AC, Stockwell BR.

Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14525-30. Epub 2007 Aug 28.

PMID:
17726098
14.

Curcumin nanoparticles attenuate neurochemical and neurobehavioral deficits in experimental model of Huntington's disease.

Sandhir R, Yadav A, Mehrotra A, Sunkaria A, Singh A, Sharma S.

Neuromolecular Med. 2014 Mar;16(1):106-18. doi: 10.1007/s12017-013-8261-y. Epub 2013 Sep 6.

PMID:
24008671
17.

The role of oxidative stress in Huntington's disease: are antioxidants good therapeutic candidates?

Gil-Mohapel J, Brocardo PS, Christie BR.

Curr Drug Targets. 2014 Apr;15(4):454-68. Review.

PMID:
24428525
18.

Sub-chronic copper pretreatment reduces oxidative damage in an experimental Huntington's disease model.

Martínez-Lazcano JC, Montes S, Sánchez-Mendoza MA, Rodríguez-Páez L, Pérez-Neri I, Boll MC, Campos-Arroyo HD, Ríos C, Pérez-Severiano F.

Biol Trace Elem Res. 2014 Dec;162(1-3):211-8. doi: 10.1007/s12011-014-0127-0. Epub 2014 Oct 16.

PMID:
25319005
19.

Iron-dependent cell death of hepatocellular carcinoma cells exposed to sorafenib.

Louandre C, Ezzoukhry Z, Godin C, Barbare JC, Mazière JC, Chauffert B, Galmiche A.

Int J Cancer. 2013 Oct 1;133(7):1732-42. doi: 10.1002/ijc.28159. Epub 2013 Apr 8.

PMID:
23505071
20.

Ferroptosis is Involved in Acetaminophen Induced Cell Death.

Lőrincz T, Jemnitz K, Kardon T, Mandl J, Szarka A.

Pathol Oncol Res. 2015 Sep;21(4):1115-21. doi: 10.1007/s12253-015-9946-3. Epub 2015 May 12.

PMID:
25962350

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