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Items: 1 to 20 of 75

1.

KR-62980 suppresses lipid metabolism through inhibition of cytosolic NADP isocitrate dehydrogenase in zebrafish.

Chun HS, Shin SH, Ahn S, Shin DS, Choi SS, Ahn JH, Bae MA.

Zebrafish. 2014 Apr;11(2):122-8. doi: 10.1089/zeb.2013.0919. Epub 2014 Mar 3.

PMID:
24588364
2.

KR-62980: a novel peroxisome proliferator-activated receptor gamma agonist with weak adipogenic effects.

Kim KR, Lee JH, Kim SJ, Rhee SD, Jung WH, Yang SD, Kim SS, Ahn JH, Cheon HG.

Biochem Pharmacol. 2006 Aug 14;72(4):446-54. Epub 2006 May 12.

PMID:
16797489
3.

Cytosolic NADP+-dependent isocitrate dehydrogenase plays a key role in lipid metabolism.

Koh HJ, Lee SM, Son BG, Lee SH, Ryoo ZY, Chang KT, Park JW, Park DC, Song BJ, Veech RL, Song H, Huh TL.

J Biol Chem. 2004 Sep 17;279(38):39968-74. Epub 2004 Jul 14.

5.

Augmentation of PPARgamma-TAZ interaction contributes to the anti-adipogenic activity of KR62980.

Jung H, Lee MS, Jang EJ, Ahn JH, Kang NS, Yoo SE, Bae MA, Hong JH, Hwang ES.

Biochem Pharmacol. 2009 Nov 15;78(10):1323-9. doi: 10.1016/j.bcp.2009.07.001. Epub 2009 Jul 8.

PMID:
19591806
6.

Neuroprotective effects of KR-62980, a new PPARγ agonist, against chemical ischemia-reperfusion in SK-N-SH cells.

Kim KY, Cho HS, Lee SH, Ahn JH, Cheon HG.

Brain Res. 2011 Feb 4;1372:103-14. doi: 10.1016/j.brainres.2010.11.062. Epub 2010 Nov 25.

PMID:
21111719
7.

Blockade of lipid accumulation by silibinin in adipocytes and zebrafish.

Suh HJ, Cho SY, Kim EY, Choi HS.

Chem Biol Interact. 2015 Feb 5;227:53-62. doi: 10.1016/j.cbi.2014.12.027. Epub 2015 Jan 2.

PMID:
25559859
8.

Peroxisome proliferator-activated receptor-gamma regulates the expression and function of very-low-density lipoprotein receptor.

Tao H, Aakula S, Abumrad NN, Hajri T.

Am J Physiol Endocrinol Metab. 2010 Jan;298(1):E68-79. doi: 10.1152/ajpendo.00367.2009. Epub 2009 Oct 27.

9.

PPARγ partial agonist GQ-16 strongly represses a subset of genes in 3T3-L1 adipocytes.

Milton FA, Cvoro A, Amato AA, Sieglaff DH, Filgueira CS, Arumanayagam AS, de Lima Mdo C, Pitta IR, de Assis Rocha Neves F, Webb P.

Biochem Biophys Res Commun. 2015 Aug 28;464(3):718-23. doi: 10.1016/j.bbrc.2015.07.011. Epub 2015 Jul 10.

PMID:
26168725
10.

Bixin regulates mRNA expression involved in adipogenesis and enhances insulin sensitivity in 3T3-L1 adipocytes through PPARgamma activation.

Takahashi N, Goto T, Taimatsu A, Egawa K, Katoh S, Kusudo T, Sakamoto T, Ohyane C, Lee JY, Kim YI, Uemura T, Hirai S, Kawada T.

Biochem Biophys Res Commun. 2009 Dec 25;390(4):1372-6. doi: 10.1016/j.bbrc.2009.10.162. Epub 2009 Nov 3.

PMID:
19891958
11.

LT175 is a novel PPARα/γ ligand with potent insulin-sensitizing effects and reduced adipogenic properties.

Gilardi F, Giudici M, Mitro N, Maschi O, Guerrini U, Rando G, Maggi A, Cermenati G, Laghezza A, Loiodice F, Pochetti G, Lavecchia A, Caruso D, De Fabiani E, Bamberg K, Crestani M.

J Biol Chem. 2014 Mar 7;289(10):6908-20. doi: 10.1074/jbc.M113.506394. Epub 2014 Jan 22.

12.

In vitro metabolism of a novel PPAR gamma agonist, KR-62980, and its stereoisomer, KR-63198, in human liver microsomes and by recombinant cytochrome P450s.

Kim KB, Seo KA, Yoon YJ, Bae MA, Cheon HG, Shin JG, Liu KH.

Xenobiotica. 2008 Sep;38(9):1165-76. doi: 10.1080/00498250802037309 .

PMID:
18609447
13.

Cytosolic aconitase activity sustains adipogenic capacity of adipose tissue connecting iron metabolism and adipogenesis.

Moreno M, Ortega F, Xifra G, Ricart W, Fernández-Real JM, Moreno-Navarrete JM.

FASEB J. 2015 Apr;29(4):1529-39. doi: 10.1096/fj.14-258996. Epub 2014 Dec 30.

14.

Differential anti-proliferative actions of peroxisome proliferator-activated receptor-gamma agonists in MCF-7 breast cancer cells.

Kim KY, Kim SS, Cheon HG.

Biochem Pharmacol. 2006 Aug 28;72(5):530-40. Epub 2006 Jun 27.

PMID:
16806087
15.

Kaempferol suppresses lipid accumulation by inhibiting early adipogenesis in 3T3-L1 cells and zebrafish.

Lee YJ, Choi HS, Seo MJ, Jeon HJ, Kim KJ, Lee BY.

Food Funct. 2015 Aug;6(8):2824-33. doi: 10.1039/c5fo00481k. Epub 2015 Jul 15.

PMID:
26174858
16.

C333H, a novel PPARalpha/gamma dual agonist, has beneficial effects on insulin resistance and lipid metabolism.

Xu C, Wang LL, Liu HY, Zhou XB, Cao YL, Li S.

Acta Pharmacol Sin. 2006 Feb;27(2):223-8.

17.

RNA interference of PPARgamma using fiber-modified adenovirus vector efficiently suppresses preadipocyte-to-adipocyte differentiation in 3T3-L1 cells.

Hosono T, Mizuguchi H, Katayama K, Koizumi N, Kawabata K, Yamaguchi T, Nakagawa S, Watanabe Y, Mayumi T, Hayakawa T.

Gene. 2005 Mar 28;348:157-65.

PMID:
15777692
18.

A peroxisome proliferator-activated receptor alpha/gamma dual agonist with a unique in vitro profile and potent glucose and lipid effects in rodent models of type 2 diabetes and dyslipidemia.

Reifel-Miller A, Otto K, Hawkins E, Barr R, Bensch WR, Bull C, Dana S, Klausing K, Martin JA, Rafaeloff-Phail R, Rafizadeh-Montrose C, Rhodes G, Robey R, Rojo I, Rungta D, Snyder D, Wilbur K, Zhang T, Zink R, Warshawsky A, Brozinick JT.

Mol Endocrinol. 2005 Jun;19(6):1593-605. Epub 2005 Apr 14.

PMID:
15831517
19.

Negative regulation of adipogenesis by kaempferol, a component of Rhizoma Polygonati falcatum in 3T3-L1 cells.

Park UH, Jeong JC, Jang JS, Sung MR, Youn H, Lee SJ, Kim EJ, Um SJ.

Biol Pharm Bull. 2012;35(9):1525-33.

20.

6-gingerol inhibits rosiglitazone-induced adipogenesis in 3T3-L1 adipocytes.

Tzeng TF, Chang CJ, Liu IM.

Phytother Res. 2014 Feb;28(2):187-92. doi: 10.1002/ptr.4976. Epub 2013 Mar 21.

PMID:
23519881

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