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Items: 1 to 20 of 122

1.

Positive regulation of TRAF6-dependent innate immune responses by protein phosphatase PP1-γ.

Opaluch AM, Schneider M, Chiang CY, Nguyen QT, Maestre AM, Mulder LC, Secundino I, De Jesus PD, König R, Simon V, Nizet V, MacLeod G, Varmuza S, Fernandez-Sesma A, Chanda SK.

PLoS One. 2014 Feb 20;9(2):e89284. doi: 10.1371/journal.pone.0089284. eCollection 2014.

2.

TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase.

Wang W, Huang X, Xin HB, Fu M, Xue A, Wu ZH.

J Biol Chem. 2015 May 22;290(21):13372-85. doi: 10.1074/jbc.M115.643767. Epub 2015 Apr 10.

3.

E3 ubiquitin ligase tripartite motif 38 negatively regulates TLR-mediated immune responses by proteasomal degradation of TNF receptor-associated factor 6 in macrophages.

Zhao W, Wang L, Zhang M, Yuan C, Gao C.

J Immunol. 2012 Mar 15;188(6):2567-74. doi: 10.4049/jimmunol.1103255. Epub 2012 Feb 8.

4.

The TLR2 ligand FSL-1 and the TLR5 ligand Flagellin mediate pro-inflammatory and pro-labour response via MyD88/TRAF6/NF-κB-dependent signalling.

Lim R, Barker G, Lappas M.

Am J Reprod Immunol. 2014 May;71(5):401-17. doi: 10.1111/aji.12229. Epub 2014 Mar 17.

PMID:
24635133
5.

MyD88 adapter-like (Mal)/TIRAP interaction with TRAF6 is critical for TLR2- and TLR4-mediated NF-kappaB proinflammatory responses.

Verstak B, Nagpal K, Bottomley SP, Golenbock DT, Hertzog PJ, Mansell A.

J Biol Chem. 2009 Sep 4;284(36):24192-203. doi: 10.1074/jbc.M109.023044. Epub 2009 Jul 10.

6.

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB.

Schneider M, Zimmermann AG, Roberts RA, Zhang L, Swanson KV, Wen H, Davis BK, Allen IC, Holl EK, Ye Z, Rahman AH, Conti BJ, Eitas TK, Koller BH, Ting JP.

Nat Immunol. 2012 Sep;13(9):823-31. doi: 10.1038/ni.2378. Epub 2012 Aug 5.

7.

Tribbles 2 (Trib2) is a novel regulator of toll-like receptor 5 signaling.

Wei SC, Rosenberg IM, Cao Z, Huett AS, Xavier RJ, Podolsky DK.

Inflamm Bowel Dis. 2012 May;18(5):877-88. doi: 10.1002/ibd.22883. Epub 2012 Jan 23.

8.

UBE2O negatively regulates TRAF6-mediated NF-κB activation by inhibiting TRAF6 polyubiquitination.

Zhang X, Zhang J, Zhang L, van Dam H, ten Dijke P.

Cell Res. 2013 Mar;23(3):366-77. doi: 10.1038/cr.2013.21. Epub 2013 Feb 5.

10.

Coordinated regulation of Toll-like receptor and NOD2 signaling by K63-linked polyubiquitin chains.

Abbott DW, Yang Y, Hutti JE, Madhavarapu S, Kelliher MA, Cantley LC.

Mol Cell Biol. 2007 Sep;27(17):6012-25. Epub 2007 Jun 11.

11.

TRAF6 establishes innate immune responses by activating NF-kappaB and IRF7 upon sensing cytosolic viral RNA and DNA.

Konno H, Yamamoto T, Yamazaki K, Gohda J, Akiyama T, Semba K, Goto H, Kato A, Yujiri T, Imai T, Kawaguchi Y, Su B, Takeuchi O, Akira S, Tsunetsugu-Yokota Y, Inoue J.

PLoS One. 2009 May 25;4(5):e5674. doi: 10.1371/journal.pone.0005674.

12.

Inhibition of TIR domain signaling by TcpC: MyD88-dependent and independent effects on Escherichia coli virulence.

Yadav M, Zhang J, Fischer H, Huang W, Lutay N, Cirl C, Lum J, Miethke T, Svanborg C.

PLoS Pathog. 2010 Sep 23;6(9):e1001120. doi: 10.1371/journal.ppat.1001120.

13.

Dynamic Arginine Methylation of Tumor Necrosis Factor (TNF) Receptor-associated Factor 6 Regulates Toll-like Receptor Signaling.

Tikhanovich I, Kuravi S, Artigues A, Villar MT, Dorko K, Nawabi A, Roberts B, Weinman SA.

J Biol Chem. 2015 Sep 4;290(36):22236-49. doi: 10.1074/jbc.M115.653543. Epub 2015 Jul 28.

14.

TAK1-ECSIT-TRAF6 complex plays a key role in the TLR4 signal to activate NF-κB.

Wi SM, Moon G, Kim J, Kim ST, Shim JH, Chun E, Lee KY.

J Biol Chem. 2014 Dec 19;289(51):35205-14. doi: 10.1074/jbc.M114.597187. Epub 2014 Nov 4.

15.

Phosphatase holoenzyme PP1/GADD34 negatively regulates TLR response by inhibiting TAK1 serine 412 phosphorylation.

Gu M, Ouyang C, Lin W, Zhang T, Cao X, Xia Z, Wang X.

J Immunol. 2014 Mar 15;192(6):2846-56. doi: 10.4049/jimmunol.1302537. Epub 2014 Feb 17. Erratum in: J Immunol. 2015 Aug 1;195(3):1331-2.

16.

34 kDa MOMP of Shigella flexneri promotes TLR2 mediated macrophage activation with the engagement of NF-kappaB and p38 MAP kinase signaling.

Pore D, Mahata N, Pal A, Chakrabarti MK.

Mol Immunol. 2010 May;47(9):1739-46. doi: 10.1016/j.molimm.2010.03.001. Epub 2010 Mar 27.

PMID:
20347487
17.

Expression of TRAF6 and pro-inflammatory cytokines through activation of TLR2, TLR4, NOD1, and NOD2 in human periodontal ligament fibroblasts.

Tang L, Zhou XD, Wang Q, Zhang L, Wang Y, Li XY, Huang DM.

Arch Oral Biol. 2011 Oct;56(10):1064-72. doi: 10.1016/j.archoralbio.2011.02.020. Epub 2011 Mar 31.

PMID:
21457942
18.

Toxoplasma gondii GRA7-Induced TRAF6 Activation Contributes to Host Protective Immunity.

Yang CS, Yuk JM, Lee YH, Jo EK.

Infect Immun. 2015 Nov 9;84(1):339-50. doi: 10.1128/IAI.00734-15.

19.

IRF-8/interferon (IFN) consensus sequence-binding protein is involved in Toll-like receptor (TLR) signaling and contributes to the cross-talk between TLR and IFN-gamma signaling pathways.

Zhao J, Kong HJ, Li H, Huang B, Yang M, Zhu C, Bogunovic M, Zheng F, Mayer L, Ozato K, Unkeless J, Xiong H.

J Biol Chem. 2006 Apr 14;281(15):10073-80. Epub 2006 Feb 16.

20.

MyD88-dependent silencing of transgene expression during the innate and adaptive immune response to helper-dependent adenovirus.

Suzuki M, Cerullo V, Bertin TK, Cela R, Clarke C, Guenther M, Brunetti-Pierri N, Lee B.

Hum Gene Ther. 2010 Mar;21(3):325-36. doi: 10.1089/hum.2009.155.

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