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Items: 1 to 20 of 143

1.

T cells and macrophages responding to oxidative damage cooperate in pathogenesis of a mouse model of age-related macular degeneration.

Cruz-Guilloty F, Saeed AM, Duffort S, Cano M, Ebrahimi KB, Ballmick A, Tan Y, Wang H, Laird JM, Salomon RG, Handa JT, Perez VL.

PLoS One. 2014 Feb 19;9(2):e88201. doi: 10.1371/journal.pone.0088201. eCollection 2014.

2.

A hapten generated from an oxidation fragment of docosahexaenoic acid is sufficient to initiate age-related macular degeneration.

Hollyfield JG, Perez VL, Salomon RG.

Mol Neurobiol. 2010 Jun;41(2-3):290-8. doi: 10.1007/s12035-010-8110-z. Epub 2010 Mar 12.

3.

Infiltration of proinflammatory m1 macrophages into the outer retina precedes damage in a mouse model of age-related macular degeneration.

Cruz-Guilloty F, Saeed AM, Echegaray JJ, Duffort S, Ballmick A, Tan Y, Betancourt M, Viteri E, Ramkhellawan GC, Ewald E, Feuer W, Huang D, Wen R, Hong L, Wang H, Laird JM, Sene A, Apte RS, Salomon RG, Hollyfield JG, Perez VL.

Int J Inflam. 2013;2013:503725. doi: 10.1155/2013/503725. Epub 2013 Mar 7.

4.

The oxidative stress product carboxyethylpyrrole potentiates TLR2/TLR1 inflammatory signaling in macrophages.

Saeed AM, Duffort S, Ivanov D, Wang H, Laird JM, Salomon RG, Cruz-Guilloty F, Perez VL.

PLoS One. 2014 Sep 3;9(9):e106421. doi: 10.1371/journal.pone.0106421. eCollection 2014.

5.

Carboxyethylpyrrole oxidative protein modifications stimulate neovascularization: Implications for age-related macular degeneration.

Ebrahem Q, Renganathan K, Sears J, Vasanji A, Gu X, Lu L, Salomon RG, Crabb JW, Anand-Apte B.

Proc Natl Acad Sci U S A. 2006 Sep 5;103(36):13480-4. Epub 2006 Aug 25. Erratum in: Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15722.

6.

Retinal Pigment Epithelial Cell Apoptosis is Influenced by a Combination of Macrophages and Soluble Mediators Present in Age-Related Macular Degeneration.

Devarajan G, Niven J, Forrester JV, Crane IJ.

Curr Eye Res. 2016 Sep;41(9):1235-44. doi: 10.3109/02713683.2015.1109129. Epub 2016 Mar 25.

PMID:
27015409
7.

Carboxyethylpyrrole protein adducts and autoantibodies, biomarkers for age-related macular degeneration.

Gu X, Meer SG, Miyagi M, Rayborn ME, Hollyfield JG, Crabb JW, Salomon RG.

J Biol Chem. 2003 Oct 24;278(43):42027-35. Epub 2003 Aug 15.

8.

γδ T cells as a major source of IL-17 production during age-dependent RPE degeneration.

Zhao Z, Xu P, Jie Z, Zuo Y, Yu B, Soong L, Sun J, Chen Y, Cai J.

Invest Ophthalmol Vis Sci. 2014 Sep 11;55(10):6580-9. doi: 10.1167/iovs.14-15166.

9.

Oxidative damage-induced inflammation initiates age-related macular degeneration.

Hollyfield JG, Bonilha VL, Rayborn ME, Yang X, Shadrach KG, Lu L, Ufret RL, Salomon RG, Perez VL.

Nat Med. 2008 Feb;14(2):194-8. doi: 10.1038/nm1709. Epub 2008 Jan 27.

10.

Clearance of autophagy-associated dying retinal pigment epithelial cells - a possible source for inflammation in age-related macular degeneration.

Szatmári-Tóth M, Kristóf E, Veréb Z, Akhtar S, Facskó A, Fésüs L, Kauppinen A, Kaarniranta K, Petrovski G.

Cell Death Dis. 2016 Sep 8;7(9):e2367. doi: 10.1038/cddis.2016.133.

11.

Increased Th1/Th17 Responses Contribute to Low-Grade Inflammation in Age-Related Macular Degeneration.

Chen J, Wang W, Li Q.

Cell Physiol Biochem. 2017;44(1):357-367. doi: 10.1159/000484907. Epub 2017 Nov 13.

12.

Impairing autophagy in retinal pigment epithelium leads to inflammasome activation and enhanced macrophage-mediated angiogenesis.

Liu J, Copland DA, Theodoropoulou S, Chiu HA, Barba MD, Mak KW, Mack M, Nicholson LB, Dick AD.

Sci Rep. 2016 Feb 5;6:20639. doi: 10.1038/srep20639.

13.

Retinal pigment epithelium and microglia express the CD5 antigen-like protein, a novel autoantigen in age-related macular degeneration.

Iannaccone A, Hollingsworth TJ, Koirala D, New DD, Lenchik NI, Beranova-Giorgianni S, Gerling IC, Radic MZ, Giorgianni F.

Exp Eye Res. 2017 Feb;155:64-74. doi: 10.1016/j.exer.2016.12.006. Epub 2016 Dec 15.

14.

Bmp6 regulates retinal iron homeostasis and has altered expression in age-related macular degeneration.

Hadziahmetovic M, Song Y, Wolkow N, Iacovelli J, Kautz L, Roth MP, Dunaief JL.

Am J Pathol. 2011 Jul;179(1):335-48. doi: 10.1016/j.ajpath.2011.03.033. Epub 2011 May 3.

15.

NLRP3 Upregulation in Retinal Pigment Epithelium in Age-Related Macular Degeneration.

Wang Y, Hanus JW, Abu-Asab MS, Shen D, Ogilvy A, Ou J, Chu XK, Shi G, Li W, Wang S, Chan CC.

Int J Mol Sci. 2016 Jan 8;17(1). pii: E73. doi: 10.3390/ijms17010073.

16.

Pentraxin 3 recruits complement factor H to protect against oxidative stress-induced complement and inflammasome overactivation.

Wang L, Cano M, Datta S, Wei H, Ebrahimi KB, Gorashi Y, Garlanda C, Handa JT.

J Pathol. 2016 Dec;240(4):495-506. doi: 10.1002/path.4811.

PMID:
27659908
17.

Oxidative stress-induced premature senescence dysregulates VEGF and CFH expression in retinal pigment epithelial cells: Implications for Age-related Macular Degeneration.

Marazita MC, Dugour A, Marquioni-Ramella MD, Figueroa JM, Suburo AM.

Redox Biol. 2016 Apr;7:78-87. doi: 10.1016/j.redox.2015.11.011. Epub 2015 Nov 29.

18.

Amyloid-beta up-regulates complement factor B in retinal pigment epithelial cells through cytokines released from recruited macrophages/microglia: Another mechanism of complement activation in age-related macular degeneration.

Wang J, Ohno-Matsui K, Yoshida T, Shimada N, Ichinose S, Sato T, Mochizuki M, Morita I.

J Cell Physiol. 2009 Jul;220(1):119-28. doi: 10.1002/jcp.21742.

PMID:
19277984
19.

Microglia in the mouse retina alter the structure and function of retinal pigmented epithelial cells: a potential cellular interaction relevant to AMD.

Ma W, Zhao L, Fontainhas AM, Fariss RN, Wong WT.

PLoS One. 2009 Nov 20;4(11):e7945. doi: 10.1371/journal.pone.0007945.

20.

Interleukin-18 induces retinal pigment epithelium degeneration in mice.

Ijima R, Kaneko H, Ye F, Nagasaka Y, Takayama K, Kataoka K, Kachi S, Iwase T, Terasaki H.

Invest Ophthalmol Vis Sci. 2014 Sep 18;55(10):6673-8. doi: 10.1167/iovs.14-15367.

PMID:
25237159

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