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Items: 1 to 20 of 102

1.

DDX3X-MLLT10 fusion in adults with NOTCH1 positive T-cell acute lymphoblastic leukemia.

Brandimarte L, La Starza R, Gianfelici V, Barba G, Pierini V, Di Giacomo D, Cools J, Elia L, Vitale A, Luciano L, Bardi A, Chiaretti S, Matteucci C, Specchia G, Mecucci C.

Haematologica. 2014 May;99(5):64-6. doi: 10.3324/haematol.2013.101725. Epub 2014 Feb 28. No abstract available.

PMID:
24584351
2.

New MLLT10 gene recombinations in pediatric T-acute lymphoblastic leukemia.

Brandimarte L, Pierini V, Di Giacomo D, Borga C, Nozza F, Gorello P, Giordan M, Cazzaniga G, Te Kronnie G, La Starza R, Mecucci C.

Blood. 2013 Jun 20;121(25):5064-7. doi: 10.1182/blood-2013-02-487256. Epub 2013 May 14.

PMID:
23673860
3.

Mutations of PHF6 are associated with mutations of NOTCH1, JAK1 and rearrangement of SET-NUP214 in T-cell acute lymphoblastic leukemia.

Wang Q, Qiu H, Jiang H, Wu L, Dong S, Pan J, Wang W, Ping N, Xia J, Sun A, Wu D, Xue Y, Drexler HG, Macleod RA, Chen S.

Haematologica. 2011 Dec;96(12):1808-14. doi: 10.3324/haematol.2011.043083. Epub 2011 Aug 31.

PMID:
21880637
4.

A novel TRB@/NOTCH1 fusion gene in T-cell lymphoblastic lymphoma with t(7;9)(q34;q34).

Yamamoto K, Nakamachi Y, Yakushijin K, Miyata Y, Okamura A, Kawano S, Matsuoka H, Minami H.

Eur J Haematol. 2013 Jan;90(1):68-75. doi: 10.1111/ejh.12019. Epub 2012 Nov 29.

PMID:
23033986
5.

RNA sequencing unravels the genetics of refractory/relapsed T-cell acute lymphoblastic leukemia. Prognostic and therapeutic implications.

Gianfelici V, Chiaretti S, Demeyer S, Di Giacomo F, Messina M, La Starza R, Peragine N, Paoloni F, Geerdens E, Pierini V, Elia L, Mancini M, De Propris MS, Apicella V, Gaidano G, Testi AM, Vitale A, Vignetti M, Mecucci C, Guarini A, Cools J, Foà R.

Haematologica. 2016 Aug;101(8):941-50. doi: 10.3324/haematol.2015.139410. Epub 2016 May 5.

PMID:
27151993
6.

DDX5 is a positive regulator of oncogenic NOTCH1 signaling in T cell acute lymphoblastic leukemia.

Lin S, Tian L, Shen H, Gu Y, Li JL, Chen Z, Sun X, You MJ, Wu L.

Oncogene. 2013 Oct;32(40):4845-53. doi: 10.1038/onc.2012.482. Epub 2012 Oct 29.

PMID:
23108395
7.

[Expression of SET-NUP214 fusion gene in patients with T-cell acute lymphoblastic leukemia and its clinical significance].

Dai HP, Wang Q, Wu LL, Ping NN, Wu CX, Xie JD, Pan JL, Xue YQ, Wu DP, Chen SN.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2012 Oct;20(5):1047-51. Chinese.

PMID:
23114116
8.

The prognosis of CALM-AF10-positive adult T-cell acute lymphoblastic leukemias depends on the stage of maturation arrest.

Ben Abdelali R, Asnafi V, Petit A, Micol JB, Callens C, Villarese P, Delabesse E, Reman O, Lepretre S, Cahn JY, Guillerm G, Berthon C, Gardin C, Corront B, Leguay T, Béné MC, Ifrah N, Leverger G, Dombret H, Macintyre E.

Haematologica. 2013 Nov;98(11):1711-7. doi: 10.3324/haematol.2013.086082. Epub 2013 Jul 5.

PMID:
23831922
9.

The NOTCH1-MYC highway toward T-cell acute lymphoblastic leukemia.

Sanchez-Martin M, Ferrando A.

Blood. 2017 Mar 2;129(9):1124-1133. doi: 10.1182/blood-2016-09-692582. Epub 2017 Jan 23. Review.

PMID:
28115368
10.

T-ALL pathogenesis requires a NOTCH1-driven MYC enhancer.

[No authors listed]

Cancer Discov. 2014 Nov;4(11):OF17. doi: 10.1158/2159-8290.CD-RW2014-196. Epub 2014 Sep 18.

PMID:
25367958
11.

Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1.

Matsushita K, Kitamura K, Rahmutulla B, Tanaka N, Ishige T, Satoh M, Hoshino T, Miyagi S, Mori T, Itoga S, Shimada H, Tomonaga T, Kito M, Nakajima-Takagi Y, Kubo S, Nakaseko C, Hatano M, Miki T, Matsuo M, Fukuyo M, Kaneda A, Iwama A, Nomura F.

Oncotarget. 2015 Mar 10;6(7):5102-17.

PMID:
25671302
12.

NOTCH1 activation clinically antagonizes the unfavorable effect of PTEN inactivation in BFM-treated children with precursor T-cell acute lymphoblastic leukemia.

Bandapalli OR, Zimmermann M, Kox C, Stanulla M, Schrappe M, Ludwig WD, Koehler R, Muckenthaler MU, Kulozik AE.

Haematologica. 2013 Jun;98(6):928-36. doi: 10.3324/haematol.2012.073585. Epub 2013 Jan 24.

PMID:
23349303
13.

NOTCH1/FBXW7 mutation identifies a large subgroup with favorable outcome in adult T-cell acute lymphoblastic leukemia (T-ALL): a Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL) study.

Asnafi V, Buzyn A, Le Noir S, Baleydier F, Simon A, Beldjord K, Reman O, Witz F, Fagot T, Tavernier E, Turlure P, Leguay T, Huguet F, Vernant JP, Daniel F, Béné MC, Ifrah N, Thomas X, Dombret H, Macintyre E.

Blood. 2009 Apr 23;113(17):3918-24. doi: 10.1182/blood-2008-10-184069. Epub 2008 Dec 23.

PMID:
19109228
14.

SET-NUP214 fusion in acute myeloid leukemia- and T-cell acute lymphoblastic leukemia-derived cell lines.

Quentmeier H, Schneider B, Röhrs S, Romani J, Zaborski M, Macleod RA, Drexler HG.

J Hematol Oncol. 2009 Jan 23;2:3. doi: 10.1186/1756-8722-2-3.

PMID:
19166587
15.

Molecular monitoring in NUP214-ABL-positive T-acute lymphoblastic leukemia reveals clonal diversity and helps to guide targeted therapy.

Koschmieder S, Burmeister T, Brüggemann M, Berkemeier A, Volpert S, Wieacker P, Silling G, Gökbuget N, Müller-Tidow C, Berdel WE, Stelljes M.

Leukemia. 2014 Feb;28(2):419-22. doi: 10.1038/leu.2013.272. Epub 2013 Sep 19. No abstract available.

PMID:
24048416
16.

Notch1 gene mutations target KRAS G12D-expressing CD8+ cells and contribute to their leukemogenic transformation.

Kong G, Du J, Liu Y, Meline B, Chang YI, Ranheim EA, Wang J, Zhang J.

J Biol Chem. 2013 Jun 21;288(25):18219-27. doi: 10.1074/jbc.M113.475376. Epub 2013 May 14. Erratum in: J Biol Chem. 2013 Dec 27;288(52):37368.

PMID:
23673656
17.

Notch1 is required for hypoxia-induced proliferation, invasion and chemoresistance of T-cell acute lymphoblastic leukemia cells.

Zou J, Li P, Lu F, Liu N, Dai J, Ye J, Qu X, Sun X, Ma D, Park J, Ji C.

J Hematol Oncol. 2013 Jan 5;6:3. doi: 10.1186/1756-8722-6-3.

PMID:
23289374
18.

Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia.

Paganin M, Ferrando A.

Blood Rev. 2011 Mar;25(2):83-90. doi: 10.1016/j.blre.2010.09.004. Epub 2010 Oct 20. Review.

PMID:
20965628
19.

An activating intragenic deletion in NOTCH1 in human T-ALL.

Haydu JE, De Keersmaecker K, Duff MK, Paietta E, Racevskis J, Wiernik PH, Rowe JM, Ferrando A.

Blood. 2012 May 31;119(22):5211-4. doi: 10.1182/blood-2011-10-388504. Epub 2012 Apr 17.

PMID:
22510873
20.

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

Yatim A, Benne C, Sobhian B, Laurent-Chabalier S, Deas O, Judde JG, Lelievre JD, Levy Y, Benkirane M.

Mol Cell. 2012 Nov 9;48(3):445-58. doi: 10.1016/j.molcel.2012.08.022. Epub 2012 Sep 27.

PMID:
23022380

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