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Items: 1 to 20 of 116

1.

Targeting tumour-supportive cellular machineries in anticancer drug development.

Dobbelstein M, Moll U.

Nat Rev Drug Discov. 2014 Mar;13(3):179-96. doi: 10.1038/nrd4201. Review.

PMID:
24577400
2.

Targeting survivin in cancer: the cell-signalling perspective.

Kanwar JR, Kamalapuram SK, Kanwar RK.

Drug Discov Today. 2011 Jun;16(11-12):485-94. doi: 10.1016/j.drudis.2011.04.001. Epub 2011 Apr 12. Review.

PMID:
21511051
3.

Heat shock proteins in cancer: targeting the 'chaperones'.

Nahleh Z, Tfayli A, Najm A, El Sayed A, Nahle Z.

Future Med Chem. 2012 May;4(7):927-35. doi: 10.4155/fmc.12.50. Review.

PMID:
22571616
4.

Recent Patents on Heat Shock Proteins Targeting Antibodies.

Fernandes JC, Alves P.

Recent Pat Anticancer Drug Discov. 2017;12(1):48-54. doi: 10.2174/1574892812666161123141516. Review.

PMID:
27881057
5.

Identification of disease-relevant genes for molecularly-targeted drug discovery.

Kauselmann G, Dopazo A, Link W.

Curr Cancer Drug Targets. 2012 Jan;12(1):1-13. Review.

PMID:
22165964
6.

Adhesion dependent signalling in the tumour microenvironment: the future of drug targetting.

Bewick MA, Lafrenie RM.

Curr Pharm Des. 2006;12(22):2833-48. Review.

PMID:
16918414
7.

Targeting apoptosis pathways in cancer therapy.

Fulda S, Debatin KM.

Curr Cancer Drug Targets. 2004 Nov;4(7):569-76. Review.

PMID:
15578914
8.

Targeting multiple kinase pathways: a change in paradigm.

Gossage L, Eisen T.

Clin Cancer Res. 2010 Apr 1;16(7):1973-8. doi: 10.1158/1078-0432.CCR-09-3182. Epub 2010 Mar 9. Review.

9.

Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism.

Pathania D, Millard M, Neamati N.

Adv Drug Deliv Rev. 2009 Nov 30;61(14):1250-75. doi: 10.1016/j.addr.2009.05.010. Epub 2009 Aug 27. Review.

PMID:
19716393
10.

Human pregnane X receptor: a novel target for anticancer drug development.

Rathod V, Jain S, Nandekar P, Sangamwar AT.

Drug Discov Today. 2014 Jan;19(1):63-70. doi: 10.1016/j.drudis.2013.08.009. Epub 2013 Aug 22. Review.

PMID:
23974067
11.

Therapeutic potential of drugs to modulate DNA repair in cancer.

Curtin N.

Expert Opin Ther Targets. 2007 Jun;11(6):783-99. Review.

PMID:
17504016
12.

The polyamine transport system as a target for anticancer drug development.

Palmer AJ, Wallace HM.

Amino Acids. 2010 Feb;38(2):415-22. doi: 10.1007/s00726-009-0400-2. Epub 2009 Dec 3. Review.

PMID:
19956998
13.

Targeting mitochondria in the treatment of human cancer: a coordinated attack against cancer cell energy metabolism and signalling.

Hagland H, Nikolaisen J, Hodneland LI, Gjertsen BT, Bruserud Ø, Tronstad KJ.

Expert Opin Ther Targets. 2007 Aug;11(8):1055-69. Review.

PMID:
17665978
14.

Current and potential anticancer drugs targeting members of the UHRF1 complex including epigenetic modifiers.

Unoki M.

Recent Pat Anticancer Drug Discov. 2011 Jan;6(1):116-30. Review.

PMID:
21110828
15.

Notch Signaling in Cancer: Rationale and Strategies for Targeting.

Alketbi A, Attoub S.

Curr Cancer Drug Targets. 2015;15(5):364-74. Review.

PMID:
26239151
16.

Epigenetic opportunities and challenges in cancer.

Best JD, Carey N.

Drug Discov Today. 2010 Jan;15(1-2):65-70. doi: 10.1016/j.drudis.2009.10.010. Epub 2009 Nov 6. Review.

PMID:
19897050
17.

Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal.

Tsuruo T, Naito M, Tomida A, Fujita N, Mashima T, Sakamoto H, Haga N.

Cancer Sci. 2003 Jan;94(1):15-21. Review.

18.

CNIO cancer conference: targeted search for anticancer drugs.

Fischer PM.

Expert Opin Investig Drugs. 2003 Jun;12(6):1039-44.

PMID:
12783608
19.

Drugging the p53 pathway: understanding the route to clinical efficacy.

Khoo KH, Verma CS, Lane DP.

Nat Rev Drug Discov. 2014 Mar;13(3):217-36. doi: 10.1038/nrd4236. Review. Erratum in: Nat Rev Drug Discov. 2014 Apr;13(4):314. Hoe, Khoo Kian [corrected to Khoo, Kian Hoe].

PMID:
24577402
20.

Development of ligand-targeted liposomes for cancer therapy.

Noble CO, Kirpotin DB, Hayes ME, Mamot C, Hong K, Park JW, Benz CC, Marks JD, Drummond DC.

Expert Opin Ther Targets. 2004 Aug;8(4):335-53. Review.

PMID:
15268628

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